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Monocyte-derived Inflammatory Dendritic Cells in the Granuloma During Mycobacterial Infection

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Current Topics in Innate Immunity II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 946))

Abstract

The monocyte-derived, inflammatory dendritic cell subset plays an important role during immune responses against infections. This review will focus on the complex, changing role of this subset during mycobacterial infection. Studies demonstrate that in addition to sustaining a systemic anti-mycobacterial response, the inflammatory dendritic cell subset present in Mycobacterium-induced granulomas also influences local immune regulation within the granuloma over the course of infection. This review will also survey the literature on how similar and different inflammatory dendritic cell subsets during other infections.

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Authors and Affiliations

  1. Department of Pathology and Laboratory Sciences, University of Wisconsin, 53705, Madison, WI, USA

    Heidi A. Schreiber & Matyas Sandor

  2. Institut Curie, INSERM U932, Immunité et Cancer, 75248, Paris Cedex 05, France

    Heidi A. Schreiber

Authors
  1. Heidi A. Schreiber
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  2. Matyas Sandor
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Correspondence to Matyas Sandor .

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Editors and Affiliations

  1. Department Of Pathology Laboratory Of, Medicine, University Of Pennsylvania, Johnson Pavilion 410, Philadelphia, 19104, Pennsylvania, USA

    John D. Lambris

  2. Health Sciences Center, University of Louisville, Louisville, 40292, Kentucky, USA

    George Hajishengallis

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Schreiber, H.A., Sandor, M. (2012). Monocyte-derived Inflammatory Dendritic Cells in the Granuloma During Mycobacterial Infection. In: Lambris, J., Hajishengallis, G. (eds) Current Topics in Innate Immunity II. Advances in Experimental Medicine and Biology, vol 946. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0106-3_16

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