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Influence of Nutrition on Metabolism of Carcinogens

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Advances in Nutritional Research

Part of the book series: Advances in Nutritional Research ((ANUR,volume 2))

Abstract

The recognition that nutrition has an important bearing on the determination of cancer risk has received support in many quarters in the last few years. Moreover, foods which supply these nutrients may also contain a large variety of nonnutrient, adventitious components, some of which may be carcinogenic. Various epidemiological estimates during the last ten years have generally agreed that 80–90% of all human cancers are associated with the environment and/or ingestion of carcinogenic chemicals (Doll, 1967; Boyland, 1967; Higginson, 1969). However, we know very little about the fundamental mechanisms which account for these relationships. One hypothesis that should be considered is the possibility that nutritional status may play a role through modification of enzyme activities which are responsible for carcinogen metabolism.

This research was supported by grants from Hoffmann-LaRoche Research Foundation and National Institutes of Health (R01 ES 00336, R01 CA 20079).

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  1. Department of Nutritional Biochemistry, Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA

    T. Colin Campbell

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  1. University of Guelph, Guelph, Ontario, Canada

    Harold H. Draper

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Campbell, T.C. (1979). Influence of Nutrition on Metabolism of Carcinogens. In: Draper, H.H. (eds) Advances in Nutritional Research. Advances in Nutritional Research, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-9931-5_2

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