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Epidemiology and Clues to the Etiology of Neural Tube Defects

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The Pediatric Spine I

Part of the book series: Principles of Pediatric Neurosurgery ((PRINCPEDIATR))

Abstract

Since the pioneering studies of Record and McKeown1 published in 1949 an increasing number of epidemiologic surveys have been conducted to gather information on the etiology of neural tube defects (NTD). This accounts for the evolution from the puzzled attitude of the past to the present plans for primary prevention. Although a definitive answer to the interlacing thread of questions and apparent contradictions arising from different sources is far from available, some evidence is now clearly discernible, indicating clues to further knowledge and indications for interventional programs.

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Authors
  1. Rita P. M. Luciano
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  2. Francesco Velardi
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Editors and Affiliations

  1. Dipartimento di Neurochirurgia, Universita degli Studi, 37020, Gargagnago, Verona, Italy

    Anthony J. Raimondi M.D.

  2. Northwestern University Medical School, Chicago, Illinois, USA

    Anthony J. Raimondi M.D.

  3. Hôpital des Enfants de la Timone, Rue Saint Pierre, 13005, Marseille, France

    Maurice Choux M.D.

  4. Istituto di Neurochirurgia, Università Cattolica del Sacro Cuore, Largo Gemelli 8, 00168, Rome, Italy

    Concezio Di Rocco M.D.

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Luciano, R.P.M., Velardi, F. (1989). Epidemiology and Clues to the Etiology of Neural Tube Defects. In: Raimondi, A.J., Choux, M., Di Rocco, C. (eds) The Pediatric Spine I. Principles of Pediatric Neurosurgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8820-3_6

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  • DOI: https://doi.org/10.1007/978-1-4613-8820-3_6

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