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Tardive Dyskinesia and Developmental Disabilities

  • Chapter
Psychopharmacology of the Developmental Disabilities

Part of the book series: Disorders of Human Learning, Behavior, and Communication ((HUMAN LEARNING))

Abstract

Neuroleptic drugs are commonly used in the management of individuals with mental retardation, autism and other pervasive developmental disorders, and Tourette syndrome. Analysis of the risks and features of tardive dyskinesia in these populations is difficult because of the problems of defining tardive dyskinesia in children, definition of patient populations, a high background level of preexisting involuntary movements, and the frequent use of other medications that also are active on the central nervous system. Review of the literature documents that individuals in all of these patient groups are at risk for the development of tardive dyskinesia, although its prevalence is not clear. As these drugs are effective therapeutically in many circumstances, a detailed cost-benefit analysis must be developed for each patient and combined with regularly scheduled monitoring for the presence of a dyskinesia. It has also been demonstrated that a number of other drugs can cause a syndrome resembling tardive dyskinesia. The situation can only be clarified by appropriate drug withdrawals and challenges.

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Authors
  1. Gerald S. Golden
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Editors and Affiliations

  1. Nisonger Center for Mental Retardation, The Ohio State University, 43210-1205, Columbus, Ohio, USA

    Michael G. Aman

  2. Educational Research Services Center, 60115, De Kalb, Illinois, USA

    Nirbhay N. Singh

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© 1988 Springer-Verlag New York Inc.

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Golden, G.S. (1988). Tardive Dyskinesia and Developmental Disabilities. In: Aman, M.G., Singh, N.N. (eds) Psychopharmacology of the Developmental Disabilities. Disorders of Human Learning, Behavior, and Communication. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8774-9_9

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  • DOI: https://doi.org/10.1007/978-1-4613-8774-9_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8776-3

  • Online ISBN: 978-1-4613-8774-9

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