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The Cardiomyopathies

  • Chapter
Congestive Heart Failure

Abstract

The concept of primary myocardial disease was first suggested in the late 19th century by Krehl, who described several cases of “chronic myocarditis” in which autopsied hearts demonstrated myocardial degeneration, hypertrophy, and inflammation.1 The term “primary myocardial disease” was coined by Josserand and Gallavardin at the beginning of this century.2 But it was not until 1957 that the introduction of the term “cardiomyopathy,” by Brigden, was used to describe myocardial disease of unknown etiology and in the absence of coronary disease.3 Subsequently, in 1968 the terminology was specifically defined by the World Health Organization as myocardial disease excluding vascular, hypertension, and valvular disease. It was further broken down into “primary” and “secondary” cardiomyopathy depending on unknown or known etiologies, respectively.4

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References

  1. Krehl L. Beitrag zur Kentniss der idiopathischen Herzmuskelerkrankungen. Dtsch Arch F Klin Med. 1891; 48:414–431.

    Google Scholar 

  2. Josserand E, Gallavardin L. De l’asystole progressive des jeunes sujets par myocardite subaigue primitive. Arch Gen Med. 1901;6:684–704.

    Google Scholar 

  3. Brigden W. Uncommon myocardial diseases. The noncoronary cardiomyopathies. Lancet. 1957;2:1243–1249.

    Google Scholar 

  4. Fejfar Z. Accounts of international meetings: idiopathic cardiomegaly. Bull WHO. 1968;28:979–992.

    Google Scholar 

  5. WHO:ISFC Task Force. Report on the WHO/ISFC task force on the definition and classification of cardiomyopathies. Br Heart J. 1980;44:672–673.

    Google Scholar 

  6. Douglas PS, Morrow R, Ioli A, Reichek N. Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy. J Am Coll Cardiol. 1989;13: 311–315.

    PubMed  CAS  Google Scholar 

  7. Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest. 1975;56:56–64.

    PubMed  CAS  Google Scholar 

  8. O’Keefe DD, Hoffman JIE, Cheitlin R, O’Neill, MJ, Allard JR, Shapkin E. Coronary blood flow in experimental canine left ventricular hypertrophy. Circ Res. 1978;43:43–51.

    PubMed  Google Scholar 

  9. Limas CJ, Olivari MT, Goldenberg IF, Levine TB, Benditt DG, Simon A. Calcium uptake by cardiac sarcoplasmic reticulum in human dilated cardiomyopathy. Cardiovasc Res. 1987;21:601–605.

    PubMed  CAS  Google Scholar 

  10. Bristow MR, Ginsburg R, Minobe W, et al. Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med. 1982;307:205–211.

    PubMed  CAS  Google Scholar 

  11. Heilbrunn SM, Shah P, Bristow MR, Valentine HA, Ginsburg R, Fowler MB. Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy. Circulation. 1989;79:483–490.

    PubMed  CAS  Google Scholar 

  12. Feldman AM, Cates AE, Veazey WB, et al. Increase of the 40,000-mol. wt. pertussis toxin substrate (G protein) in the failing human heart. J Clin Invest. 1988;82:189–197.

    PubMed  CAS  Google Scholar 

  13. Bohm M, Gierschik P, Jakobs KH, et al. Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy. Circulation. 1990;82:1249–1265.

    PubMed  CAS  Google Scholar 

  14. Bohm M, Ungerer M, Erdmann E. Beta adrenoceptors and M-cholinoceptors in myocardium of hearts with coronary artery disease or idiopathic dilated cardiomyopathy removed at cardiac transplantation. Am J Cardiol. 1990;66:880–882.

    PubMed  CAS  Google Scholar 

  15. Walsh RA, Henkel R, Robbins J. Cardiac myocin heavy- and light-chain gene expression in hypertrophy and heart disease. Heart Failure. 1990–91;6:238–243.

    Google Scholar 

  16. Robinson JA, O’Connell JB. Myocarditis: precursor of cardiomyopathy. Lexington, MA: Collamore Press; 1983.

    Google Scholar 

  17. Hosenpud JD. Chronic idiopathic myocarditis: controversies in causes and therapy. Cardiovasc Rev Rep. 1988;9:31–37.

    Google Scholar 

  18. Reyes MP, Lerner AM. Coxsackievirus myocarditis-with special reference to acute and chronic effects. Prog Cardiovasc Dis. 1985;27:373–394.

    PubMed  CAS  Google Scholar 

  19. Woodruff JF. Viral myocarditis. Am J Pathol. 1980;101:427–479.

    Google Scholar 

  20. Daly K, Richardson PJ, Olsen EGJ, et al. Acute myocarditis—role of histological and virological examination in the diagnosis and assessment of immunosuppressive treatment. Br Heart J. 1984;51:30–35.

    PubMed  CAS  Google Scholar 

  21. Bowles NE, Rose ML, Taylor P, et al. End-stage dilated cardiomyopathy; persistence of enterovirus RNA in myocardium at cardiac transplantation and lack of immune response. Circulation. 1989;80:1128–1136.

    PubMed  CAS  Google Scholar 

  22. Kandolf R, Ameis D, Kirschner P, Canu A, Hofschneider PH. In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: an approach to the diagnosis of viral heart disease. Proc Natl Acad Sci USA. 1987;84:6272–6276.

    PubMed  CAS  Google Scholar 

  23. Limas CJ, Limas C. HLA antigens in idiopathic dilated cardiomyopathy. Br Heart J. 1989;62:379–383.

    PubMed  CAS  Google Scholar 

  24. Koike S. Immunological disorders in patients with dilated cardiomyopathy. Jpn Heart J. 1989;30:799–807.

    PubMed  CAS  Google Scholar 

  25. Schultheiss HP, Schulze K, Kuhl U, Ulrich G, Klingenberg M. The ADP/ATP carrier as a mitochondrial autoantigen—facts and perspectives. Ann NY Acad Sci. 1986;488:44–64.

    PubMed  CAS  Google Scholar 

  26. Schulze K, Becker BF, Schultheiss HP. Antibodies to the ADP/ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo. Circ Res. 1989;64:179–192.

    PubMed  CAS  Google Scholar 

  27. Schulze K, Becker BF, Schauer R, Schultheiss HP. Antibodies to ADP/ATP Carrier-an autoantigen in myocarditis and dilated cardiomyopathy-impair cardiac function. Circulation. 1990;81:959–969.

    PubMed  CAS  Google Scholar 

  28. Limas CJ, Limas C, Kubo SH, Olivari MT. Anti-beta receptor antibodies in human dilated cardiomyopathy and correlation with HLA-DR antigens. Am J Cardiol. 1990;65:483–487.

    PubMed  CAS  Google Scholar 

  29. Hosenpud JD, Campbell SM, Mendelson DJ. Interleukin-1 induced myocardial depression in an isolated perfused beating heart preparation. J Heart Transplant. 1989;8:460–464.

    PubMed  CAS  Google Scholar 

  30. Hosenpud JD, Campbell SM, Pan G. Indirect inhibition of myocyte RNA and protein synthesis by interleukin-1. J Mol Cell Cardiol. 1990;22:213–225.

    PubMed  CAS  Google Scholar 

  31. Factor SM, Minase T, Cho S, Dominitz R, Sonnenblick EH. Microvascular spasm in the cardiomyopathic Syrian hamster: a preventable cause of focal myocardial necrosis. Circulation. 1982;66:342–354.

    PubMed  CAS  Google Scholar 

  32. Leonard DA, Sonnenblick EH, LeJemtel TH. Endocrine cardiomyopathies. Heart Failure. 1985;July/August: 179–186.

    Google Scholar 

  33. Treasure CB, Vita JA, Cox DA, et al. Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy. Circulation. 1990; 81:772–779.

    PubMed  CAS  Google Scholar 

  34. van Hoeven KH, Factor SM. Endomyocardial biopsy diagnosis of small vessel disease: a clinicopathologic study. Int J Cardiol. 1990;26:103–110.

    PubMed  Google Scholar 

  35. Demakis JG, Proskey A, Rahimtoola SH, et al. The natural course of alcoholic cardiomyopathy. Ann Intern Med. 1974;80:293–297.

    PubMed  CAS  Google Scholar 

  36. Kantrowitz NE, Bristow MR. Cardiotoxicity of antitumor agents. Prog Cardiovasc Dis. 1984;27:195–200.

    PubMed  CAS  Google Scholar 

  37. Bristow MR, Mason JW, Billingham ME, Daniels JR. Dose-effect and structure-function relationships in doxorubicin cardiomyopathy. Am Heart J. 1981;102:709–718.

    PubMed  CAS  Google Scholar 

  38. Perloff JK, De Leon AC Jr, O’Doherty D. The cardiomyopathy of progressive muscular dystrophy. Circulation. 1966;33:625–648.

    PubMed  CAS  Google Scholar 

  39. Alboliras ET, Shub C, Gomez MR, et al. Spectrum of cardiac involvement in Friedreich’s ataxia: clinical, electrocardiographic and echocardiographic observations. Am J Cardiol. 1986;58:518–524.

    PubMed  CAS  Google Scholar 

  40. Caforio ALP, Rossi B, Risaliti R, et al. Type 1 fiber abnormalities in skeletal muscle of patients with hypertrophic and dilated cardiomyopathy: evidence of subclinical myogenic myopathy. J Am Coll Cardiol. 1989;14:1464–1473.

    PubMed  CAS  Google Scholar 

  41. Fuster V, Gersh BJ, Giuliani ER, Tajik AJ, Brandenburg RO, Frye RL. The natural history of idiopathic dilated cardiomyopathy. Am J Cardiol. 1981;47:525–531.

    PubMed  CAS  Google Scholar 

  42. Schwarz F, Mall G, Zebe H, et al. Determinants of survival in patients with congestive cardiomyopathy: quantitative morphologic findings and left ventricular hemodynamics. Circulation. 1984;70:923–928.

    PubMed  CAS  Google Scholar 

  43. Regan TJ, Levinson GE, Oldewurtel HA, Frank MJ, Weisse AB, Moschos CB. Ventricular function in non-cardiacs with alcoholic fatty liver: role of ethanol in the production of cardiomyopathy. J Clin Invest. 1969;48:397–407.

    PubMed  CAS  Google Scholar 

  44. Lang RM, Borow KM, Neumann A, Feldman T. Adverse cardiac effects of acute alcohol ingestion in young adults. Ann Intern Med. 1985;102:742–747.

    PubMed  CAS  Google Scholar 

  45. Vasdev SC, Chakravarti RN, Subrahmanyam D, Jain AC, Wahi PL. Myocardial lesions induced by prolonged alcohol feeding in rhesus monkeys. Cardiovasc Res. 1975: 9:134–140.

    PubMed  CAS  Google Scholar 

  46. Regan TJ, Khan MI, Ettinger PO, et al. Myocardial function and lipid metabolism in the chronic alcoholic animal. J Clin Invest. 1974;54:740–752.

    PubMed  CAS  Google Scholar 

  47. Thomas G, Haider B, Oldewurtel HA, Lyons MM, Yeh CK, Regan TJ. Progression of myocardial abnormalities in experimental alcoholism. Am J Cardiol. 1980;46:233–241.

    PubMed  CAS  Google Scholar 

  48. Wu S, White R, Wikman-Coffelt J, et al. The preventive effect of verapamil on ethanol-induced cardiac depression: phosphorous-31 nuclear magnetic resonance and high-pressure liquid chromatographic studies of hamsters. Circulation. 1987;75:1058–1064.

    PubMed  CAS  Google Scholar 

  49. Segal LD, Rendig SV, Mason DT. Alcohol-induced cardiac hemodynamic and Ca2+ flux and dysfunctions are reversible. J Mol Cell Cardiol. 1981;13:443–455.

    Google Scholar 

  50. Sarma JSM, Ikeda S, Fischer R, Maruyama Y, Weishaar R, Bing RJ. Biochemical and contractile properties of heart muscle after prolonged alcohol administration. J Mol Cell Cardiol. 1976;8:951–972.

    PubMed  CAS  Google Scholar 

  51. Polimeni, PI, Hoeschen O, Hoeschen LE. In vivo effects of ethanol on the rat myocardium: evidence for a reversible, non-specific increase of sarcolemmal permeability. J Mol Cell Cardiol. 1983;15:113–122.

    PubMed  CAS  Google Scholar 

  52. Noren GR, Staley NA, Einzig S, Mikell FL, Asinger RW. Alcohol-induced congestive cardiomyopathy: an animal model. Cardiovasc Res. 1983;17:81–87.

    PubMed  CAS  Google Scholar 

  53. Reitz RC, Helsabeck E, Mason DP. Effects of chronic alcohol ingestion on the fatty acid composition of the heart. Lipids. 1973;8:80–84.

    PubMed  CAS  Google Scholar 

  54. Burch GE, Giles, TD. Alcoholic cardiomyopathy: concept of the disease and its treatment. Am J Med. 1971;50:141–145.

    PubMed  CAS  Google Scholar 

  55. Koide T, Machida K, Nakanishi A, Ozeki K, Mashima S, Kono H. Cardiac abnormalities in chronic alcoholism. An evidence suggesting association of myocardial abnormality with chronic alcoholism in 107 Japanese patients admitted to a psychiatric ward. Jpn Heart J. 1972; 13:418–427.

    PubMed  CAS  Google Scholar 

  56. McDonald CD, Burch GE, Walsh JJ. Alcoholic cardiomyopathy managed with prolonged bed rest. Ann Intern Med. 1971;74:681–691.

    PubMed  CAS  Google Scholar 

  57. Wu CF, Sudhakar M, Jaferi G, Ahmed SS, Regan TJ. Preclinical cardiomyopathy in chronic alcoholics: a sex difference. Am Heart J. 1976;91:281–286.

    PubMed  CAS  Google Scholar 

  58. Lefkowitch JH, Fenoglio JJ Jr. Liver disease in alcoholic cardiomyopathy: evidence against cirrhosis. Hum Pathol. 1983;14:457–463.

    PubMed  CAS  Google Scholar 

  59. Morin Y, Daniel P. Quebec beer-drinkers’ cardiomyopathy: etiological considerations. Can Med Assoc. 1967;97:926–928.

    CAS  Google Scholar 

  60. Sullivan J, Parker M, Carson SB. Tissue cobalt content in “beer drinkers’ myocardiopathy.” J Lab Clin Med. 1968;71:893–896.

    PubMed  CAS  Google Scholar 

  61. Shugoll GI, Bowen PJ, Moore JP, Lenkin ML. Follow-up observations and prognosis in primary myocardial disease. Arch Intern Med. 1972;129:67–72.

    PubMed  CAS  Google Scholar 

  62. Rubler S, Dglugash J, Yuceoglu YZ, Kumral T, Branwood AW, Grishman A. New type of cardiomyopathy associated with diabetic glomerulosclerosis. Am J Cardiol. 1972;30:595–602.

    PubMed  CAS  Google Scholar 

  63. Kannel WB, Hjortland M, Castelli WP. Role of diabetes in congestive heart failure: the Framingham study. Am J Cardiol. 1974;34:29–34.

    PubMed  CAS  Google Scholar 

  64. Hamby RI, Zoneraich S, Sherman S. Diabetic cardiomyopathy. JAMA. 1974;229:1749–1754.

    PubMed  CAS  Google Scholar 

  65. Regan TJ, Ettinger PO, Khan MI, et al. Altered myocardial function and metabolism in chronic diabetes mellitus without ischemia in dogs. Circ Res. 1974; 35:222–237.

    CAS  Google Scholar 

  66. Lee JC, Downing SE. Coronary dynamics and myocardial metabolism in the diabetic newborn lamb. Am J Physiol. 1979;237:H118–H124.

    PubMed  CAS  Google Scholar 

  67. Haider B, Yeh CK, Thomas G, Oldewurtel HA, Lyons MM, Regan TJ. Influence of diabetes on the myocardium and coronary arteries of rhesus monkeys fed an atherogenic diet. Circ Res. 1981;49:1278–1288.

    PubMed  CAS  Google Scholar 

  68. Regan TJ, Wu CF, Yeh CK, Oldewurtel HA, Haider B. Myocardial composition and function in diabetes: the effects of chronic insulin use. Circ Res. 1981;49:1268–1277.

    PubMed  CAS  Google Scholar 

  69. Giacomelli E, Wiener J. Primary myocardial disease in the diabetic mouse: an ultrastructural study. Lab Invest. 1979;40:460–473.

    PubMed  CAS  Google Scholar 

  70. Rodrigues B, McNeill JH. Cardiac function in spontaneously hypertensive diabetic rats. Am J Physiol. 1986;20:H571–H580.

    Google Scholar 

  71. Rodgers RL. Depressor effect of diabetes in the spontaneously hypertensive rat: associated changes in heart performance. Can J Physiol Pharmacol. 1986;64:1177–1184.

    PubMed  CAS  Google Scholar 

  72. Fein FS, Kornstein LB, Strobeck JE, Capasso JM, Sonnenblick EH. Altered myocardial mechanics in diabetic rats. Circ Res. 1980;47:922–933.

    PubMed  CAS  Google Scholar 

  73. Heyliger CE, Pierce GN, Singal PK, Beamish RE, Dhalla NS. Cardiac alpha-and beta-adrenergic receptor alterations in diabetic cardiomyopathy. Basic Res Cardiol. 1982;77:610–618.

    PubMed  CAS  Google Scholar 

  74. Brownlee M, Cerami A, Viassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med. 1988;318:1315–1321.

    PubMed  CAS  Google Scholar 

  75. Ganguly PK, Pierce GN, Dhalla KS, Dhalla NS. Defective cardiac sarcoplasmic reticular calcium transport in diabetic cardiomyopathy. Am J Physiol. 1983;244:E528–E535.

    PubMed  CAS  Google Scholar 

  76. Factor SM, Minase T, Cho S, Fein F, Capasso JM, Sonnenblick EH. Coronary microvascular abnormalities in the hypertensive-diabetic rat. A primary cause of cardiomyopathy? Am J Pathol. 1984;116:9–20.

    PubMed  CAS  Google Scholar 

  77. Regan TJ, Lyons MM, Ahmed SS, et al. Evidence for cardiomyopathy in familial diabetes mellitus. J Clin Invest. 1977;60:885–899.

    Google Scholar 

  78. Ahmed SS, Jaferi GA, Narang RM, Regan TJ. Preclinical abnormaility of left ventricular function in diabetes mellitus. Am Heart J. 1975;89:153–158.

    PubMed  CAS  Google Scholar 

  79. Seneviratne BIB. Diabetic cardiomyopathy: The preclinical phase. Br Med J. 1977;1:1444–1446.

    PubMed  CAS  Google Scholar 

  80. Sykes CA, Wright AD, Malins JM, Pentecost BL. Changes in systolic time intervals during treatment of diabetes mellitus. Br Heart J. 1977;39:255–259.

    PubMed  CAS  Google Scholar 

  81. Blumenthal HT, Alex M, Goldenberg S. A study of lesions of the intramural coronary branches in diabetes mellitus. Arch Pathol. 1960;70:27–42.

    Google Scholar 

  82. Silver MD, Huckell VS, Lorber M. Basement membranes of small cardiac vessels in patients with diabetes and myxedema: preliminary observations. Pathology. 1977;9:213–220.

    PubMed  CAS  Google Scholar 

  83. Factor SM, Minase T, Sonnenblick EH. Clinical and morphological features of human hypertensive-diabetic cardiomyopathy. Am Heart J. 1980;790:446–458.

    Google Scholar 

  84. Parving HH. Impact of blood pressure and antihypertensive treatment on incipient and overt nephropathy, retinopathy and endothelial permeability in diabetes mellitus. Diabetes Care. 1991;14:260–269.

    PubMed  CAS  Google Scholar 

  85. Chase HP, Garg SK, Jackson WE, et al. Blood pressure and retinopathy in type I diabetes. Ophthalmology. 1990;97:155–159.

    PubMed  CAS  Google Scholar 

  86. Hull E, Hafkesbring E. Toxic post-partal failure. New Orleans Med Surg J. 1937;89:556–557.

    Google Scholar 

  87. Gouley BA, McMillan TM, Bellet S. Idiopathic myocardial degeneration associated with pregnancy and especially the Puerperium. Am J Med Sci. 1937;194:185–199.

    Google Scholar 

  88. Homans DC. Peripartum cardiomyopathy. N Engl J Med. 1985;312:1432–1437.

    PubMed  CAS  Google Scholar 

  89. Metcalfe J. The maternal heart in the postpartum period. Am J Cardiol. 1963;12:439–440.

    PubMed  CAS  Google Scholar 

  90. Demakis JG, Rahimtoola SH. Peripartum cardiomyopathy. Circulation. 1971;44:964–968.

    PubMed  CAS  Google Scholar 

  91. Rand RJ, Jenkins DM, Scott DG. Maternal cardiomyopathy of pregnancy causing stillbirth. Br J Obstet Gynaecol. 1975;82:172–175.

    PubMed  CAS  Google Scholar 

  92. Walsh JJ, Burch GE, Black WC, Ferrans VJ, Hibbs RG. Idiopathic myocardiopathy of the Puerperium (post-partal heart disease). Circulation. 1965;32:19–31.

    PubMed  CAS  Google Scholar 

  93. Pierce JA, Price BO, Joyce JW. Familial occurrence of postpartal heart failure. Arch Intern Med. 1963;111:651–655.

    PubMed  CAS  Google Scholar 

  94. Brown AK, Doukas N, Riding WD, Jones EW. Cardiomyopathy and pregnancy. Br Heart J. 1967;29:387–393.

    PubMed  CAS  Google Scholar 

  95. Melvin KR, Richardson PJ, Olsen EGJ, Daly K, Jackson G. Peripartum cardiomyopathy due to myocarditis. N Engl J Med. 1982;307:731–734.

    PubMed  CAS  Google Scholar 

  96. Midei MG, DeMent SH, Feldman AM, Hutchins GM, Baughman KL. Peripartum myocarditis and cardiomyopathy. Circulation. 1990;81:922–928.

    PubMed  CAS  Google Scholar 

  97. Julian DG, Szekely P. Peripartum cardiomyopathy. Prog Cardiovasc Dis. 1985;27:223–240.

    PubMed  CAS  Google Scholar 

  98. Burch GE, McDonald CD, Walsh JJ. The effect of prolonged bed rest on postpartal cardiomyopathy. Am Heart J. 1971;81:186–201.

    PubMed  CAS  Google Scholar 

  99. DeMakis JG, Rahimtoola SH, Sutton GC, et al. Natural course of peripartum cardiomyopathy. Circulation. 1971;44:1053–1061.

    PubMed  CAS  Google Scholar 

  100. Meadows WR. Idiopathic myocardial failure in the last trimester of pregnancy and the puerperium. Circulation. 1957;15:903–914.

    PubMed  CAS  Google Scholar 

  101. Billingham ME, Mason JW, Bristow MR, Daniels JR. Anthracycline cardiomyopathy monitored by morphologic changes. Cancer Treat Rep. 1978;62:865–872.

    PubMed  CAS  Google Scholar 

  102. Ferrans VJ. Overview of cardiac pathology in relation to anthracycline cardiotoxicity. Cancer Treat Rep. 1978;62:955–961.

    PubMed  CAS  Google Scholar 

  103. Mason JW, Bristow MR, Billingham ME, Daniels JR. Invasive and noninvasive methods of assessing adriamycin cardiotoxic effects in man: superiority of histopathologic assessment using endomyocardial biopsy. Cancer Treat Rep. 1978;62:857–864.

    PubMed  CAS  Google Scholar 

  104. Olson RD, Mushlin PS. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J. 1990;4:3076–3086.

    PubMed  CAS  Google Scholar 

  105. Saltiel E, McGuire W. Doxorubicin (adriamycin) cardiomyopathy. West J Med. 1983;139:332–341.

    PubMed  CAS  Google Scholar 

  106. Minow RA, Benjamin RS, Lee ET, Gottlieb JA. Adriamycin cardiomyopathy—risk factors. Cancer. 1977;39:1397–1402.

    PubMed  CAS  Google Scholar 

  107. Billngham ME, Bristow MR, Glatstein E, Mason JW, Masek MA, Daniels JR. Adriamycin cardiotoxicity: endomyocardial biopsy evidence of enhancement by irradiation. Am J Surg Pathol. 1977;1:17–23.

    Google Scholar 

  108. Billingham ME. Endomyocardial changes in anthracycline-treated patients with and without irradiation. Front Radiat Ther Oncol. 1979;13:67–81.

    Google Scholar 

  109. Torti FM, Bristow MR, Howes AE, et al. Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule. Ann Intern Med. 1983;99:745–756.

    PubMed  CAS  Google Scholar 

  110. Bristow MR, Lopez MB, Mason JW, Billingham ME, Winchester MA. Efficacy and cost of cardiac monitoring in patients receiving doxorubicin. Cancer. 1982;50:32–41.

    PubMed  CAS  Google Scholar 

  111. Neri R, Mestroni L, Salvi A, Pandullo C, Camerini F. Ventricular arrhythmias in dilated cardiomyopathy: efficacy of amiodarone. Am Heart J. 1987;113:707–715.

    PubMed  CAS  Google Scholar 

  112. Figulla HR, Rahlf G, Nieger M, Luig H, Kreuzer H. Spontaneous hemodynamic improvement or stabilization and associated biopsy findings in patients with congestive cardiomyopathy. Circulation. 1985;71:1095–1104.

    PubMed  CAS  Google Scholar 

  113. Taliercio CP, Seward JB, Driscoll DJ, Fisher LD, Gersh BJ, Tajik AJ. Idiopathic dilated cardiomyopathy in the young: clinical profile and natural history. J Am Coll Cardiol. 1985;6:1126–1131.

    PubMed  CAS  Google Scholar 

  114. Griffin ML, Hernandez A, Martin TC, et al. Dilated cardiomyopathy in infants and children. J Am Coll Cardiol. 1988;11:139–144.

    PubMed  CAS  Google Scholar 

  115. Unverferth DV, Magorien RD, Moeschberger ML, Baker PB, Fetters JK, Leier CV. Factors influencing the one-year mortality of dilated cardiomyopathy. Am J Cardiol. 1984;54:147–152.

    PubMed  CAS  Google Scholar 

  116. Wilson JR, Schwartz JS, St John Sutton M, et al. Prognosis in severe heart failure: relation to hemodynamic measurements and ventricular ectopic activity. J Am Coll Cardiol. 1983;2:403–410.

    PubMed  CAS  Google Scholar 

  117. Chew CYC, Ziady GM, Raphael MJ, Nellen M, Oakley CM. Primary restrictive cardiomyopathy non-tropical endomyocardial fibrosis and hypereosinophilic heart disease. Br Heart J. 1977;39:399–413.

    PubMed  CAS  Google Scholar 

  118. Benotti JR, Grossman W. Restrictive cardiomyopathy. Annu Rev Med. 1984;35:113–125.

    PubMed  CAS  Google Scholar 

  119. Janos GG, Arjunan K, Meyer RA, Engel P, Kaplan S. Differentiation of constrictive pericarditis and restrictive cardiomyopathy using digitized echocardiography. J Am Coll Cardiol. 1983;1(2):541–549.

    PubMed  CAS  Google Scholar 

  120. Tyberg TI, Goodyer AVN, Hurst VW III, Alexander J, Langou RA. Left ventricular filling in differentiating restrictive amyloid cardiomyopathy and constrictive pericarditis. Am J Cardiol. 1981;47:791–796.

    PubMed  CAS  Google Scholar 

  121. Benotti JR, Grossman W, Cohn PF. Clinical profile of restrictive cardiomyopathy. Circulation. 1980;61:1206–1212.

    PubMed  CAS  Google Scholar 

  122. Hosenpud JD, Niles NR. Clinical hemodynamic and endomyocardial biopsy findings in idiopathic restrictive cardiomyopathy. West J Med. 1986;144:303–306.

    PubMed  CAS  Google Scholar 

  123. Montgomery JF. Pericarditis. West J Med. 1975;127:295–308.

    Google Scholar 

  124. Siegel RJ, Shah PK, Fishbein MC. Idiopathic restrictive cardiomyopathy. Circulation. 1984;70:165–169.

    PubMed  CAS  Google Scholar 

  125. Mehta AV, Ferrer PL, Pickoff AS, et al. M-mode echocardiographic findings in children with idiopathic restrictive cardiomyopathy. Pediatr Cardiol. 1984;5:273–280.

    PubMed  CAS  Google Scholar 

  126. Sapire DW, Casta A, Swischuk LE, Casta D. Massive dilatation of the atria and coronary sinus in a child with restrictive cardiomyopathy and persistence of the left superior vena cava. Cathet Cardiovasc Diagn. 1983;9:47–53.

    PubMed  CAS  Google Scholar 

  127. Erath HG, Graham TP Jr, Smith CW, Boucek RJ Jr. Restrictive cardiomyopathy in an infant with massive biatrial enlargement and normal ventricular size and pump function. Cathet Cardiovasc Diagn. 1978;4:289–296.

    PubMed  Google Scholar 

  128. Arbustini E, Buonanno C, Trevi G, Pennelli N, Ferrans VJ, Thiene G. Cardiac ultrastructure in primary restrictive cardiomyopathy. Chest. 1983;84:236–238.

    PubMed  CAS  Google Scholar 

  129. Glenner GG. Amyloid deposits and amyloidosis. N Engl J Med. 1980;302:1283–1292.

    PubMed  CAS  Google Scholar 

  130. Olofsson BO, Bjerle P, Osterman G. Hemodynamic and angiocardiographic observations in familial amyloidosis with polyneuropathy. Acta Med Scand. 1982;212:77–81.

    PubMed  CAS  Google Scholar 

  131. Maule WF, Martin RH. Primary cardiac amyloidosis: an angiocardiographic clue to early diagnosis. Ann Intern Med. 1983;98:177–180.

    PubMed  CAS  Google Scholar 

  132. Kern MJ, Lorell BH, Grossman W. Cardiac amyloidosis masquerading as constrictive pericarditis. Cathet Cardiovasc Diagn. 1982;8:629–635.

    PubMed  CAS  Google Scholar 

  133. Edhag O, Helmers C, Samnegard H, Sjogren A, Vallin H. Two cases of myocardial disease simulating constrictive pericarditis. Scand J Thorac Cardiovasc Surg. 1977;11:225–227.

    PubMed  CAS  Google Scholar 

  134. Meaney E, Shabetai R, Bhargava V, et al. Cardiac amyloidosis, constrictive pericarditis in restrictive cardiomyopathy. Am J Cardiol. 1976;38:547–556.

    PubMed  CAS  Google Scholar 

  135. Naggar CZ. Rapid amyloid infiltration of the heart. Am J Cardiol. 1986;80:276–278.

    CAS  Google Scholar 

  136. Garcia R, Alam M. Restrictive cardiomyopathy. Henry Ford Hosp Med J. 1986;34;168–173.

    PubMed  CAS  Google Scholar 

  137. Child JS, Krivokapich J, Abbasi AS. Increased right ventricular wall thickness on echocardiography in amyloid infiltrative cardiomyopathy. Am J Cardiol. 1979;44:1391–1395.

    PubMed  CAS  Google Scholar 

  138. Child JS, Levisman JA, Abbasi AS, MacAlpin RN. Echocardiographic manifestations of infiltrative cardiomyopathy. Chest. 1976;70:726–731.

    PubMed  CAS  Google Scholar 

  139. Pierard L, Verheugt FWA, Meltzer RS, Roelandt J. Echocardiographic aspects of cardiac amyloidosis. Acta Cardiol. 1981;36:455–461.

    PubMed  CAS  Google Scholar 

  140. Kyle RA, Greipp PR. Amyloidosis (AL): clinical and laboratory feature in 229 cases. Mayo Clin Proc. 1983;58:665–683.

    PubMed  CAS  Google Scholar 

  141. Loeffler W. Endocarditis parietalis fibroplastica Mit Bluteosinophiline. Schweiz Med Wchnscr. 1930;66:817–820.

    Google Scholar 

  142. Roberts WC, Ferrans VJ. Pathologic anatomy of the cardiomyopathies. Idiopathic dilated and hypertrophic types, infiltrative types, and endomyocardial disease with and without eosinophilia. Hum Pathol. 1975;6:287–342.

    PubMed  CAS  Google Scholar 

  143. Spry CJF, Tai P-C, Davies J. The cardiotoxicity of eosinophils. Postgrad Med J. 1983;59:147–151.

    PubMed  CAS  Google Scholar 

  144. Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH. The idiopathic hypereosinophilic syndrome. Ann Intern Med. 1982;97:78–92.

    PubMed  CAS  Google Scholar 

  145. Olsen EGJ. Pathological aspects of endomyocardial fibrosis. Postgrad Med J. 1983;59:135–139.

    PubMed  CAS  Google Scholar 

  146. Cherian G, Vijayaraghavan G, Krishnaswami S, et al. Endomyocardial fibrosis: report on the hemodynamic data in 29 patients and review of the results of surgery. Am Heart J. 1983;105:659–666.

    PubMed  CAS  Google Scholar 

  147. Olsen EGJ, Spry CJF. Relation between eosinophilia and endomyocardial disease. Prog Cardiovasc Dis. 1985;27:241–254.

    PubMed  CAS  Google Scholar 

  148. Parrillo JE, Borer JS, Henry WL, Wolff SM, Fauci AS. The cardiovascular manifestations of the hypereosinophilic syndrome. Am J Med. 1979;67:572–582.

    PubMed  CAS  Google Scholar 

  149. Kudenchuk PJ, Hosenpud JD, Fletcher S. Eosinophilic endomyocardiopathy. Clin Cardiol. 1986;9:344–348.

    PubMed  CAS  Google Scholar 

  150. Solley GO, Maldonado JE, Gleich GJ, et al. Endomyocardiopathy with eosinophilia. Mayo Clin Proc. 1976;51:697–708.

    PubMed  CAS  Google Scholar 

  151. Benvenisti DS, Ultmann JE. Eosinophilic leukemia? Report of 5 cases and review of the literature. Ann Intern Med. 1969;71:732–736.

    Google Scholar 

  152. Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of 14 cases and review of the literature. Medicine. 1975;54:1–27.

    PubMed  CAS  Google Scholar 

  153. Ratner SJ, Fenoglio JJ Jr, Ursell PC. Utility of endomyocardial biopsy in the diagnosis of cardiac sarcoidosis. Chest. 1986;90:528–533.

    PubMed  CAS  Google Scholar 

  154. Cutler DJ, Isner JM, Bracey AW, et al. Hemochromatosis heart disease: an unemphasized cause of potentially reversible restrictive cardiomyopathy. Am J Med. 1980; 69:923–928.

    PubMed  CAS  Google Scholar 

  155. Kaplan A, Cohen J. Restrictive cardiomyopathy as the presenting feature of reticulum cell sarcoma. Am Heart J. 1969;77:307–314.

    PubMed  CAS  Google Scholar 

  156. Landau E, Reisin LH. LV myxoma resembling restrictive cardiomyopathy. Am Heart J. 1986;112:1356.

    PubMed  CAS  Google Scholar 

  157. Westerhof PW, van der Putte SCJ. Radiation pericarditis and myocardial fibrosis. Eur J Cardiol. 1976;4/2:213–218.

    PubMed  CAS  Google Scholar 

  158. Mortensen SA, Olsen HS, Baandrup U. Chronic anthracycline cardiotoxicity: haemodynamic and histopathological manifestations suggesting a restrictive endomyocardial disease. Br Heart J. 1986;55:274–282.

    PubMed  CAS  Google Scholar 

  159. Doherty NE, Siegel RJ. Cardiovascular manifestations of systemic lupus erythematosus. Am Heart J. 1985; 110:1257–1265.

    PubMed  CAS  Google Scholar 

  160. Navarro-Lopez F, Llorian A, Ferrer-Roca O, Betriu A, Sanz G. Restrictive cardiomyopathy in pseudoxanthoma elasticum. Chest. 1980;78:113–115.

    PubMed  CAS  Google Scholar 

  161. Papapietro SE, Rogers LW, Hudson NL, Atkinson JB, Page DL. Intramyocardial coronary arteritis and restrictive cardiomyopathy. Am Heart J. 1987;114:175–178.

    PubMed  CAS  Google Scholar 

  162. Humen DP, McKenzie FN, Kostuk WJ. Restricted myocardial compliance one year following cardiac transplantation. J Heart Transplant. 1984;3:341–345.

    Google Scholar 

  163. Young JB, Leon CA, Short D III, et al. Evolution of hemodynamics after orthotopic heart and heart-lung transplantation: early restrictive patterns persisting in an occult fashion. J Heart Transplant. 1987;6:34–43.

    PubMed  CAS  Google Scholar 

  164. Ramsey HW, Sbar S, Elliott LP, Eliot RS. The differential diagnosis of restrictive myocardiopathy and chronic constrictive pericarditis without calcification. Am J Cardiol. 1970;25:635–638.

    PubMed  CAS  Google Scholar 

  165. Chang LWM, Grollman JH Jr. Angiocardiographic differentiation of constrictive pericarditis and restrictive cardiomyopathy due to amyloidosis. Am J Roentgenol. 1978;130:451–453.

    CAS  Google Scholar 

  166. Anderson PAW. Diagnostic problem: constrictive pericarditis or restrictive cardiomyopathy? Cathet Cardiovasc Diagn. 1983;9:1–7.

    PubMed  CAS  Google Scholar 

  167. Isner JM, Carter BL, Bankoff MS, et al. Differentiation of constrictive pericarditis from restrictive cardiomyopathy by computed tomographic imaging. Am Heart J. 1983;105:1019–1025.

    PubMed  CAS  Google Scholar 

  168. Sechtem U, Higgins CB, Sommerhoff BA, Lipton MJ, Huycke EC. Magnetic resonance imaging of restrictive cardiomyopathy. Am J Cardiol. 1987;59:480–482.

    PubMed  CAS  Google Scholar 

  169. Sechtem U, Tscholakoff D, Higgins CB. MRI of the abnormal pericardium. AJR. 1986;147:245–252.

    PubMed  CAS  Google Scholar 

  170. Nye RE, Lovejoy FW, Yu PN. Clinical and hemodynamic studies of myocardial fibrosis. Circulation. 1957;16:332–338.

    PubMed  Google Scholar 

  171. Gould L. Left atrial “a” waves in primary myocardial disease, constrictive pericarditis, and arteriosclerotic heart disease. Am Heart J. 1969;77:430–431.

    PubMed  CAS  Google Scholar 

  172. Lewis BS, Gotsman MS. Maximal rate of fall of left ventricular pressure in cardiomyopathy and constrictive pericarditis. S Afr Med J. 1975;49:1287–1291.

    PubMed  CAS  Google Scholar 

  173. Schoenfeld MH, Supple EW, Dec GW Jr, Fallon JT, Palacios IF. Restrictive cardiomyopathy versus constrictive pericarditis: role of endomyocardial biopsy in avoiding unnecessary thoracotomy. Circulation. 1987;75:1012–1017.

    PubMed  CAS  Google Scholar 

  174. Braunwald E. Mechanism of action of calcium-channel-blocking agents. N Engl J Med. 1982;307:1618–1627.

    PubMed  CAS  Google Scholar 

  175. Teare D. Asymmetrical hypertrophy of the heart in young patients. Br Heart J. 1958;20:1–8.

    PubMed  CAS  Google Scholar 

  176. Maron BJ, Epstein SE. Hypertrophic Cardiomyopathy. Am J Cardiol. 1980;45:141–154.

    PubMed  CAS  Google Scholar 

  177. Clark CE, Henry WL, Epstein SE. Familial prevalence and genetic transmission of idiopathic hypertrophic subaortic stenosis. N Engl J Med. 1973;289:709–714.

    PubMed  CAS  Google Scholar 

  178. Maron BJ, Nichols PF, Pickle LW, Wesley YE, Mulvihill JJ. Patterns of inheritance in hypertrophic cardiomyopathy: assessment by M-mode and two-dimensional echocardiography. Am J Cardiol. 1984;53:1087–1094.

    PubMed  CAS  Google Scholar 

  179. Brock R. Functional obstruction of the left ventricle (acquired aortic subvalvular stenosis). Guy’s Hosp Rep. 1957;106:221–238.

    CAS  Google Scholar 

  180. Hutchins GM, Bulkley BH. Catenoid shape of the interventricular septum: possible cause of idiopathic hypertrophic subaortic stenosis. Circulation. 1978;58:392–397.

    PubMed  CAS  Google Scholar 

  181. Pearse AGE. Histochemical and electron microscopy of obstructive cardiomyopathy. In Wolstenholme GEW, O’Connor M, eds. Ciba Foundation Symposium on Cardiomyopathies. London: Churchill Livingstone; 1964;132–164.

    Google Scholar 

  182. Witzke DJ, Kay MP. Hypertrophic cardiomyopathy induced by administration of nerve growth factor. Circulation. 1976;54(suppl 2):88. Abstract.

    Google Scholar 

  183. Liew C-C, Sole MJ, Silver MD, Wigle ED. Electrophoretic profiles of nonhistone nuclear proteins of human hearts with muscular subaortic stenosis. Circ Res. 1980;46:513–519.

    PubMed  CAS  Google Scholar 

  184. Criley JM, Lewis KB, White RI Jr, Ross, RS. Pressure gradients without obstruction: a non concept of “hypertrophic subaortic stenosis.” Circulation. 1965;32:881–887.

    PubMed  CAS  Google Scholar 

  185. Stewart S, Mason DT, Braunwald E. Impaired rate of left ventricular filling in idiopathic subaortic stenosis and valvular aortic stenosis. Circulation. 1968;37:8–14.

    PubMed  CAS  Google Scholar 

  186. Sanderson JE, Gibson DG, Brown DJ, Goodwin JF. Left ventricular filling in hypertrophic cardiomyopathy: an angiographic study. Br Heart J. 1977;39:661–70.

    PubMed  CAS  Google Scholar 

  187. Hanrath P, Mathey DG, Siegert R, Bleifeld W. Left ventricular relaxation and filling pattern in different forms of left ventricular hypertrophy: an echocardiographic study. Am J Cardiol. 1980;45:15–23.

    PubMed  CAS  Google Scholar 

  188. Maron BJ, Merrill WH, Freier PA, Kent KM, Epstein SE, Morrow AG. Long-term clinical course and symptomatic status of patients after operation for hypertrophic subaortic stenosis. Circulation. 1978;57:1205–1213.

    PubMed  CAS  Google Scholar 

  189. Epstein SE, Henry WL, Clark CE, et al. Asymmetric septal hypertrophy. Ann Intern Med. 1974;81:650–680.

    Google Scholar 

  190. Goodwin JF. An appreciation of hypertrophic cardiomyopathy. Am J Med. 1980;68:797–800.

    Google Scholar 

  191. McKenna W, Deanfield J, Faruqui A, England D, Oakley C, Goodwin J. Prognosis in hypertrophic cardiomyopathy: role of age and clinical, electrocardiographic and hemodynamic features. Am J Cardiol. 1981;47:532–538.

    PubMed  CAS  Google Scholar 

  192. Braunwald E, Lambrew CT, Rockoff SD, Ross J Jr, Morrow AG. Idiopathic hypertrophic subaortic stenosis. I: a description of the disease based upon an analysis of 64 patients. Circulation. 1964;29, 30(suppl IV):3–119.

    Google Scholar 

  193. Swan DA, Bell B, Oakley CM, Goodwin J. Analysis of symptomatic course and prognosis and treatment of hypertrophic obstructive cardiomyopathy. Br Heart J. 1971;33:671–685.

    PubMed  CAS  Google Scholar 

  194. Fiddler GI, Tajik AJ, Weidman WH, McGoon DC, Ritter DG, Giuliani ER. Idiopathic hypertrophic subaortic stenosis in the young. Am J Cardiol. 1978;42:793–799.

    PubMed  CAS  Google Scholar 

  195. Nishimura RA, Giuliani ER, Brandenburg RO. Hypertrophic cardiomyopathy. CVRR. 1983;4:931–962.

    Google Scholar 

  196. Shah PM, Adelman AG, Wigle ED, et al. The natural (and unnatural) history of hypertrophic obstructive cardiomyopathy. Circ Res. 1974;34,35(suppl II):II-179–195.

    Google Scholar 

  197. Adelman AG, Wigle ED, Ranganathan N, et al. The clinical course in muscular subaortic stenosis. A retrospective and prospective study of 60 hemodynamically proved cases. Ann Intern Med. 1972;77:515–525.

    PubMed  CAS  Google Scholar 

  198. Stewart S, Schreiner B. Coexisting idiopathic hypertrophic subaortic stenosis and coronary artery disease. Clinical implication and operative management. J Thorac Cardiovasc Surg. 1981;82:278–280.

    PubMed  CAS  Google Scholar 

  199. Maron BJ, Epstein SE, Roberts WC. Hypertrophic cardiomyopathy and transmural myocardial infarction without significant atherosclerosis of the extramural coronary arteries. Am J Cardiol. 1979;43:1086–1112.

    PubMed  CAS  Google Scholar 

  200. Pichard AD, Meller J, Teichholz LE, Lipnik S, Gorlin R, Herman MV. Septal perforator compression (narrowing) in idiopathic hypertrophic subaortic stenosis. Am J Cardiol. 1977;40:310–314.

    PubMed  CAS  Google Scholar 

  201. Kostis JB, Moreyra AE, Natarajan N, Hosier M, Kuo PT, Conn HL Jr. The pathophysiology and diverse etiology of septal perforator compression. Circulation. 1979;59:913–919.

    PubMed  CAS  Google Scholar 

  202. St John Sutton MG, Tajik AJ, Smith HC, Ritman EL. Angina in idiopathic hypertrophic subaortic stenosis: a clinical correlate of regional left ventricular dysfunction; a videometric and echocardiographic study. Circulation. 1980;61:561–568.

    Google Scholar 

  203. Pitcher D, Wainwright R, Maisey M, Curry P, Sowton E. Assessment of chest pain in hypertrophic cardiomyopathy using exercise thallium-201 myocardial scintigraphy. Br Heart J. 1980;44:650–656.

    PubMed  CAS  Google Scholar 

  204. Weiss MB, Ellis K, Sciacca RR, Johnson LL, Schmidt DH, Cannon PJ. Myocardial blood flow in congestive and hypertrophic cardiomyopathy: relationship to peak wall stress and mean velocity of circumferential fiber shortening. Circulation. 1976;54:484–494.

    PubMed  CAS  Google Scholar 

  205. Hardarson T, de la Calzada CS, Curiel R, Goodwin JF. Prognosis and mortality of hypertrophic obstructive cardiomyopathy. Lancet. 1973;2:1462–1467.

    PubMed  CAS  Google Scholar 

  206. Canedo MI, Frank MJ, Abdulla AM. Rhythm disturbances in hypertrophic cardiomyopathy: prevalence, relation to symptoms and management. Am J Cardiol.1980;45:848–855.

    PubMed  CAS  Google Scholar 

  207. Ingham RE, Rossen RM, Goodman DJ, Harrison DC. Treadmill arrhythmias in patients with idiopathic hypertrophic subaortic stenosis. Chest. 1975;68:759–764.

    PubMed  CAS  Google Scholar 

  208. McKenna WJ, England D, Doi YL, Deanfield JE, Oakley C, Goodwin JF. Arrhythmia in hypertrophic cardiomyopathy. I. Influence on prognosis. Br Heart J. 1981;46:168–172.

    PubMed  CAS  Google Scholar 

  209. Maron BJ, Savage DD, Wolfson JK, Epstein SE. Prognostic significance of 24-hour ambulatory electrocardiographic monitoring in patients with hypertrophic cardiomyopathy: a prospective study. Am J Cardiol. 1981;48:252–257.

    PubMed  CAS  Google Scholar 

  210. Cosio FG, Moro C, Alonso M, de la Calzada CS, Llovet A. The Q-waves of hypertrophic cardiomyopathy. An electrophysiologic study. N Engl J Med. 1980;302:96–99.

    PubMed  CAS  Google Scholar 

  211. Goodwin JF, Kirkler DM. Arrhythmia as a cause of sudden death in hypertrophic cardiomyopathy. Lancet. 1976;2:937–940.

    PubMed  CAS  Google Scholar 

  212. Frank S, Braunwald E. Idiopathic hypertrophic subaortic stenosis: clinical analysis of 126 patients with emphasis on the natural history. Circulation. 1968; 37:759–788.

    PubMed  CAS  Google Scholar 

  213. Prescott R, Quinn JS, Littman D. Electrocardiographic changes in hypertrophic subaortic stenosis which stimulates myocardial infarction. Am Heart J. 1963;66:42–48.

    PubMed  CAS  Google Scholar 

  214. St. John Sutton MG, Tajik AJ, Gibson DG, Brown DJ, Seward JB, Giuliani ER. Echocardiographic assessment of left ventricular filling and septal and posterior wall dynamics in idiopathic hypertrophic subaortic stenosis. Circulation. 1978;57:512–520.

    Google Scholar 

  215. Hanrath P, Mathey D, Siegert R, Blefield W. Left ventricular relaxation and filling pattern in different forms of left ventricular hypertrophy. An echocardiographic study. Am J Cardiol. 1980;45:15–23.

    PubMed  CAS  Google Scholar 

  216. Sanderson JE, Traill TA, St John Sutton MG, Brown DJ, Gibson DG, Goodwin JF. Left ventricular relaxation and filling in hypertrophic cardiomyopathy. An echocardiographic study. Br Heart J. 1978;40:596–601.

    PubMed  CAS  Google Scholar 

  217. Murgo JP, Alter BR, Dorethy JF, Altobelli SA, McGranaham GM Jr, Dunne TE. Dynamics of left ventricular ejection in obstructive and nonobstructive hypertrophic cardiomyopathy. J Clin Invest. 1980;66:1369–1382.

    PubMed  CAS  Google Scholar 

  218. Stewart S, Mason DT, Braunwald E. Impaired rate of left ventricular filling in idiopathic hypertrophic subaortic stenosis and valvular aortic stenosis. Circulation. 1968;37:8–14.

    PubMed  CAS  Google Scholar 

  219. Wigle ED, Marquis Y, Auger P. Muscular subaortic stenosis: initial left ventricular inflow tract pressure in the assessment of intraventricular pressure differences in man. Circulation. 1967;35:1110–1117.

    Google Scholar 

  220. Shaver JA, Salerni R, Curtiss EI, Follansbee WP. Clinical presentation and noninvasive evaluation of the patient with hypertrophic cardiomyopathy. Cardiovasc Clin. 1989;19:149–192.

    Google Scholar 

  221. Adelman AG, McLoughlin MJ, Marquis Y, Auger P, Wigle ED. Left ventricular cineangiographic observations in muscular subaortic stenosis. Am J Cardiol. 1969;24:689–697.

    PubMed  CAS  Google Scholar 

  222. Whalen RE, Cohen AL, Sumner RG, Mc Intosh HD. Demonstration of the dynamic nature of idiopathic hypertrophic subaortic stenosis. Am J Cardiol. 1963;11:8–17.

    PubMed  CAS  Google Scholar 

  223. Simon AR, Ross J Jr, Gault JH. Angiographic anatomy of the left ventricle and mitral valve in idiopathic hypertrophic subaortic stenosis. Circulation. 1967;36:852–867.

    PubMed  CAS  Google Scholar 

  224. Glancy DL, O’Brien KP, Gold HK, Epstein SE. Atrial fibrillation in patients with idiopathic hypertrophic subaortic stenosis. Br Heart J. 1970;32:652–659.

    PubMed  CAS  Google Scholar 

  225. Murgo JP. The hemodynamic evaluation in hypertrophic cardiomyopathy: systolic and diastolic dysfunction. Cardiovasc Clin. 1989;19:193–220.

    Google Scholar 

  226. Harrison DC, Braunwald E, Glick G, Mason DT, Chidsey CA, Ross J Jr. Effects of beta adrenergic blockade on the circulation, with particular reference to observations in patients with hypertrophic subaortic stenosis. Circulation. 1964;29:84–98.

    PubMed  CAS  Google Scholar 

  227. Flamm MD, Harrison DC, Hancock EW. Muscular subaortic stenosis. Prevention of outflow obstruction with propranolol. Circulation. 1968;38:846–858.

    PubMed  CAS  Google Scholar 

  228. Stenson RE, Flamm MD Jr, Harrison DC, Hancock EW. Hypertrophic subaortic stenosis. Clinical and hemodynamic effects of long-term propranolol therapy. Am J Cardiol. 1973;31:763–773.

    PubMed  CAS  Google Scholar 

  229. de la Calzada CS, Ziady GM, Hardarson T, Curiel R, Goodwin JF. Effect of acute administration of propranolol on ventricular function in hypertrophic obstructive cardiomyopathy measured by non-invasive techniques. Br Heart J. 1976;38:798–803.

    Google Scholar 

  230. Swanton RH, Brooksby IAB, Jenkins BS, Webb-Peploe MM. Hemodynamic studies of beta blockade in hypertrophic obstructive cardiomyopathy. Eur J Cardiol. 1977;5:327–341.

    PubMed  CAS  Google Scholar 

  231. Speiser KW, Krayenbuehl HP. Reappraisal of the effect of acute beta-blockade on left ventricular filling dynamics in hypertrophic obstructive cardiomyopathy. Eur Heart J. 1981;2:21–29.

    PubMed  CAS  Google Scholar 

  232. Hess OM, Grimm J, Krayenbuehl HP. Diastolic function in hypertrophic cardiomyopathy: effects of propranolol and verapamil on diastolic stiffness. Eur Heart J. 1983;4(suppl F):47–56.

    PubMed  Google Scholar 

  233. Kaltenbach M, Hopf R, Kober G, Bussman W-D, Keller M, Petersen Y. Treatment of hypertrophic obstructive cardiomyopathy with verapamil. Br Heart J. 1979;42:35–42.

    PubMed  CAS  Google Scholar 

  234. Rosing DR, Condit JR, Maron BJ, et al. Verapamil therapy: a new approach to the pharmacologic treatment of hypertrophic cardiomyopathy. III. Effects of long-term administration. Am J Cardiol. 1981;48:545–553.

    PubMed  CAS  Google Scholar 

  235. Rosin DR, Idanpaan-Heikkla U, Maron BJ, Bonow RO, Epstein SE. Use of calcium channel blocking drugs in hypertrophic cardiomyopathy. Am J Cardiol. 1985;55:185B–195B.

    Google Scholar 

  236. Bonow RO, Dilsizian V, Rosing DR, Maron BJ, Bacharach SL, Green MV. Verapamil-induced improvement in left ventricular diastolic filling and increased exercise tolerance in patients with hypertrophic cardiomyopathy: short and long term effects. Circulation. 1985;72:853–864.

    PubMed  CAS  Google Scholar 

  237. Rosing DR, Kent KM, Maron BJ, Epstein SE. Verapamil therapy: a new approach to the pharmacologic treatment of hypertrophic cardiomyopathy. II. Effects on exercise capacity and symptomatic status. Circulation. 1979;60:1208–1213.

    PubMed  CAS  Google Scholar 

  238. Shaffer EM, Rocchini AP, Spicer RL, et al. Effects of verapamil on left ventricular diastolic filling in children with hypertrophic cardiomyopathy. Am J Cardiol. 1988;61:413–417.

    PubMed  CAS  Google Scholar 

  239. Bonow RO, Vitale DF, Maron BJ, Bacharach SL, Frederick TM, Green MV. Regional left ventricular asynchrony and impaired global filling in hypertrophic cardiomyopathy: Effect of verapamil. J Am Coll Cardiol. 1987;9:1108–1116.

    PubMed  CAS  Google Scholar 

  240. Bonow RO, Ostrow HG, Rosing DR, et al. Verapamil effects on left ventricular systolic and diastolic function in patients with hypertrophic cardiomyopathy: pressure-volume analysis with a non-imaging scintillation probe. Circulation. 1983;68:1062–1073.

    PubMed  CAS  Google Scholar 

  241. Ito Y, Suko J, Chidsey CA. Intracellular calcium and myocardial contractility. V. Calcium uptake of sarcoplasmic reticulum fractions in hypertrophied and failing rabbit hearts. J Mol Cell Cardiol. 1974;6:237–247.

    PubMed  CAS  Google Scholar 

  242. Lorell BH, Barry WH. Effects of verapamil on contraction and relaxation of cultured chick embryo ventricular cells during calcium overload. J Am Coll Cardiol. 1984;3:341–348.

    PubMed  CAS  Google Scholar 

  243. Paulus WJ, Nellens P, Heyndrickx GR, Andries SE. Effects of long-term treatment with amiodarone on exercise hemodynamics and left ventricular relaxation in patients with hypertrophic cardiomyopathy. Circulation. 1986;74:544–554.

    PubMed  CAS  Google Scholar 

  244. Leon MB, Rosing DR, Maron BJ, Bonow RO, Lesko LJ, Epstein SE. Amiodarone in patients with hypertrophic cardiomyopathy and refractory cardiac symptoms: an alternative to current medical therapy. Circulation. 1984;70(suppl II):II-18. Abstract.

    Google Scholar 

  245. Morrow AG, Brockenbrough EC. Surgical treatment of idiopathic hypertrophic subaortic stenosis: technic and hemodynamic results of subaortic ventriculomyotomy. Ann Surg. 1961;154:181–189.

    PubMed  CAS  Google Scholar 

  246. Morrow AG. Hypertrophic subaortic stenosis. J Thorac Cardiovasc Surg. 1978;76:423–430.

    PubMed  CAS  Google Scholar 

  247. Canedo MI, Frank MJ. Therapy of hypertrophic cardiomyopathy: medical or surgical? Clinical and pathophysiologic considerations. Am J Cardiol. 1981;48:383–388.

    PubMed  CAS  Google Scholar 

  248. Cecchi F, Maron BJ, Epstein SE. Long-term outcome of patients with hypertrophic cardiomyopathy successfully resuscitated after cardiac arrest. J Am Coll Cardiol. 1989;13:1283–1288.

    PubMed  CAS  Google Scholar 

  249. Spirito P, Chiarella F, Carratino L, Berisso MZ, Bellotti P, Vecchio C. Clinical course and prognosis of hypertrophic cardiomyopathy in an outpatient population. N Engl J Med. 1989;320:749–755.

    PubMed  CAS  Google Scholar 

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Hosenpud, J.D. (1994). The Cardiomyopathies. In: Hosenpud, J.D., Greenberg, B.H. (eds) Congestive Heart Failure. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8315-4_13

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