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Androgen Receptors in Testis Tissue Enriched in Sertoli Cells

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Hormonal Regulation of Spermatogenesis

Part of the book series: Current topics in Molecular Endocrinology ((CTME,volume 2))

Abstract

A specific receptor for androgens is present in the tubular compartment of the testis. In contrast to androgen binding protein (ABP) this receptor protein is located intracellularly, and can be demonstrated both in cytoplasmic and nuclear fractions (1–3). In mature rats the steroid bound by this receptor is mainly testosterone (1,2) and in immature rats both dihydrotestosterone and testosterone are bound (3).

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References

  1. Mulder, E., Peters, M.J., Van Beurden, W.M.O. and van der Molen, H.J.; FEBS letters 47: 209, 1974.

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  2. Mulder, E., Peters, M.J., de Vries, J. and van der Molen, H.J.; Mol. Cell. Endocr. 2: 171, 1975.

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  3. Hansson, V., McLean, W.S., Smith, A.A., Tindall, D.J., Weddington, S.C., Nayfeh, S.N., French, F.S. and Ritzen, E.M.; Steroids 23: 823, 1974.

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  4. Vonberswordt-Wallrabe, R. and Mehing, M.; J. Steroid Biochem. 5: 380, 1974.

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  5. Means, A.R. and Huckins, C.; in Hormone Binding and Target Cell Activation in the Testis, Dufau, M.L. and Means, A.R. (eds), Plenum Press, p. 145–165.

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  6. Mulder, E., van Beurden, W.M.O., de Boer, W., Brinkmann, A.O. and van der Molen, H.J.: in Hormone Binding and Target Cell Activation in the Testis, Dufau, M.L. and Means, A.R. (eds), Plenum Press, p. 343–355.

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Author information

Authors and Affiliations

  1. Department of Biochemistry (Division of Chemical Endocrinology, Medical Faculty Erasmus University Rotterdam, Rotterdam, The Netherlands

    Eppo Mulder, Marjan J. Peters & Henk J. van der Molen

Authors
  1. Eppo Mulder
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  2. Marjan J. Peters
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  3. Henk J. van der Molen
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Editor information

Editors and Affiliations

  1. University of Carolina, USA

    Frank S. French

  2. Rikshospitalet, Oslo, Norway

    Vidar Hansson

  3. Karolinska Sjukhuset, Stockholm, Sweden

    E. Martin Ritzen

  4. University of North Carolina, USA

    Shihadeh N. Nayfeh

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© 1975 Plenum Press, New York

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Mulder, E., Peters, M.J., van der Molen, H.J. (1975). Androgen Receptors in Testis Tissue Enriched in Sertoli Cells. In: French, F.S., Hansson, V., Ritzen, E.M., Nayfeh, S.N. (eds) Hormonal Regulation of Spermatogenesis. Current topics in Molecular Endocrinology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4440-7_20

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  • DOI: https://doi.org/10.1007/978-1-4613-4440-7_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4442-1

  • Online ISBN: 978-1-4613-4440-7

  • eBook Packages: Springer Book Archive

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