Abstract
The primary objective of coupling chemical fractionation and genetic bioassay techniques for particulate organics is the identification of potentially genotoxic components associated with the collected particles. There are, however, other objectives which can be of major importance. These objectives include: determining the primary sources of particles with genotoxic properties, understanding chemical transformation in the atmosphere, determining exposure levels of toxic airborne agents and assisting in the design of control technology. The number of references integrating the chemical analysis of air particulate organics with the bioassay of those organics is relatively few. The purpose of this review is to demonstrate, with these and other related references, the approaches that one may use in identifying genotoxic substances associated with air particles.
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© 1982 Plenum Press, New York
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Claxton, L.D. (1982). Review of Fractionation and Bioassay Characterization Techniques for the Evaluation of Organics Associated with Ambient Air Particles. In: Tice, R.R., Costa, D.L., Schaich, K.M. (eds) Genotoxic Effects of Airborne Agents. Environmental Science Research, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3455-2_3
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DOI: https://doi.org/10.1007/978-1-4613-3455-2_3
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