Abstract
The lysosome with its diverse content of hydrolytic enzymes has the capacity to degrade virtually every macromolecule of biological origin. Precise control of this self-destructive potential provides eukaryotic cells with the means for intracellular digestion and the means for adaptation to changes in nutritional and hormonal variables. Intracellular digestion of exogenous material taken into cells by pinocytosis or phagocytosis provides substrate for the synthesis of new cellular organelles and enzymes. Endogenous macromolecules and pieces of cytoplasmic material sequestered and digested by lysosomes during autophagia enable redirected physiological function as cellular components are degraded and resynthe sized. These lysosomal mechanisms appear to be involved in the pinocytosis of the uterine lumenal epithelium during the preimplantation period of pregnancy, the penetration of the lumenal epithelium by the blastocyst, and the extensive remodeling of the endometrial stroma during decidualization.
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© 1981 Plenum Press, New York
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Moulton, B.C., Elangovan, S. (1981). Lysosomal Mechanisms in Blastocyst Implantation and Early Decidualization. In: Glasser, S.R., Bullock, D.W. (eds) Cellular and Molecular Aspects of Implantation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3180-3_26
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DOI: https://doi.org/10.1007/978-1-4613-3180-3_26
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