Abstract
Although insects lack adaptive immune systems endowed with memory elements and finely tuned discriminatory powers such as those found in the vertebrates, they do possess internal defense mechanisms for combating foreign materials (Salt, 1970). Among these are the cellular responses of phagocytosis and encapsulation used to resist parasitic and microbial infections. These processes do not involve opsonization of foreign materials (Scott, 1971; Anderson et al., 1973), so it appears that the insect hemocyte surfaces themselves must play the crucial role in discriminating nonself from self. This being the case, analysis of insect defense reactions requires study of hemocyte surface receptor sites on which extracellular cues operate as well as investigation of the body’s own tissue surfaces to which the hemocytes remain neutral.
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Rizki, T.M., Rizki, R.M. (1984). The Cellular Defense System of Drosophila melanogaster . In: King, R.C., Akai, H. (eds) Insect Ultrastructure. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2715-8_16
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