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Use of the Echocardiogram for Identifying Infarct Expansion

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Acute Coronary Care 1987

Part of the book series: Acute Coronary Care Updates ((ACCU,volume 2))

Abstract

In its capacity for repeated non-invasive examination, echocardiography some years ago raised the attractive possibility of serial evaluation of left ventricular size and shape in acute myocardial infarction. The initial impetus for using two-dimensional echocardiography in this way was provided by the pathologists. Post mortem studies of patients dying within 30 days after acute myocardial infarction had shown that up to 2/3 of such patients had some thinning and dilatation of the infarcted area within one week of infarction (1) and that in approximately 1/3 of patients’ hearts with transmural infarcts there was marked expansion of the infarcted zone, resulting in obvious cardiac dilatation. This process occurred with little or no histologic evidence of infarct extension or further necrosis after the initial acute event.

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References

  1. Hutchins GM, Bulkley BH. Infarct expansion versus extension: Two different complications of acute myocardial infarction. Am J Cardiol 41:1127–1140, 1978.

    Article  PubMed  CAS  Google Scholar 

  2. Eaton LW, Weiss JL, Bulkley BH, Garrison GB, Weisfeldt ML. Regional cardiac dilatation after acute myocardial infarction. N Engl J Med 300:57–62, 1979.

    Article  PubMed  CAS  Google Scholar 

  3. Garrison JB, Weiss JL, Maughan WL, Tuck OM, Guier WJ, Fortuin NJ. Quantifying regional wall notion and thickening in two-dimensional echocardiography with a computer-aided contouring system. In: Computers in Cardiololgy, Long Beach, California, IEEE, 1977, p 25–25.

    Google Scholar 

  4. Shanoff HM, Little JA, Csima A, Yano R. Heart size and ten year survival after uncomplicated myocardial infarction. Am Heart J 78:608–614, 1969.

    Article  PubMed  CAS  Google Scholar 

  5. Kostuk WJ, Kazamias TM, Gander MP, Simon AL, Ross J Jr. Left ventricular size after acute myocardial infarction. Serial changes and their prognostic significance. Circulation 47:1174–1179, 1973.

    PubMed  CAS  Google Scholar 

  6. Bigger JT, Heller CA, Wenger TL. Risk stratification after acute myocardial infarction. Am J Cardiol 42:202–210, 1978.

    Article  PubMed  CAS  Google Scholar 

  7. Battler A, Karliner JS, Higgins CB, Slutsky R, Gilpin EA, Froelicher VF, Ross J. The initial chest x-ray in acute myocardial infarction: Prediction of early and late mortality and survival. Circulation 61:1004–1009, 1980.

    PubMed  CAS  Google Scholar 

  8. Erlebacher JA, Weiss JL, Weisfeldt ML, Bulkley BH. Early dilation of the infarcted segment in acute transmural myocardial enlargement. J Am Coll Cardiol 4:201–208, 1984.

    Article  PubMed  CAS  Google Scholar 

  9. Schlichter J, Hellerstein HK, Katz LA. Aneurysm of the heart: A correlative study of one hundred and two proved cases. Medicine 33:43–86, 1954.

    Article  PubMed  CAS  Google Scholar 

  10. Cabin HS, Roberts WC. True left ventricular aneurysm and healed myocardial infarction. Clinical and necropsy observations including quantification of degrees of coronary arterial narrowing. Am J Cardiol 46:754–763, 1980.

    Article  PubMed  CAS  Google Scholar 

  11. Erlebacher JA, Weiss JL, Eaton LW, Kallman C, Weisfeldt ML, Bulkley BH. Late effects of acute infarct dilation on heart size: A two dimensional echocardiographic study. Am J Cardiol 46:1120–1126, 1982.

    Article  Google Scholar 

  12. Eaton LW, Bulkley BH. Expansion of acute myocardial infarction: Its relationship to infarct morphology in a canine model. Circ Res 49:80–88, 1981.

    PubMed  CAS  Google Scholar 

  13. Hochman JS, Bulkley BH. Expansion of acute myocardial infarction: An experimental study. Circulation 65:1446–1450, 1982.

    Article  PubMed  CAS  Google Scholar 

  14. Weisman HF, Bush DE, Mannisi JA, Bulkley BH. Global cardiac remodeling after acute myocardial infarction: A study in the rat model. J Am Coll Cardiol 5:1355–1362, 1985.

    Article  PubMed  CAS  Google Scholar 

  15. Schuster EH, Bulkley BH. Expansion of transmural myocardial infarction: A pathophysiological factor in cardiac rupture. Circulation 60:1532–1538, 1979.

    PubMed  CAS  Google Scholar 

  16. Grossman W, Jones D, McLauren LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 56:56–64, 1975.

    Article  PubMed  CAS  Google Scholar 

  17. Nicklas JM, Becker LC, Bulkley BH. Ultrasonic detection of regional shape changes after acute transmural myocardial infarction: Time course in the dog model, (abstr) Am J Cardiol 49: 1038, 1982.

    Article  Google Scholar 

  18. Gottlieb SO, Gerstenblith G, Shapiro EP, Chandra N, Healy B, Weisfeldt ML, Weiss JL. Nifedipine reduces early infarct expansion: Results of a double-blind, randomized trial. Circulation 72:III–274, 1985.

    Google Scholar 

  19. Jugdutt BI, Wortman C, Warnica WJ. Does nitroglycerin therapy in acute myocardial infarction reduce the incidence of infarct expansion? J Am Coll Cardiol 5:447, 1985.

    Google Scholar 

  20. Pfeffer JM, Pfeffer MA, Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res 57:84–95, 1985.

    PubMed  CAS  Google Scholar 

  21. Rubin SA, Fishbein MC, Swan HJC. Compensatory hypertrophy in the heart after myocardial infarction in the rat. J Am Coll Cardiol 1: 1435–1441, 1983.

    Article  PubMed  CAS  Google Scholar 

  22. Bush DE, Weisman HF, Bulkley BH. Effect of infarct expansion on non-infarcted myocardium: Evidence for inadequate compensatory hypertrophy. Clin Res 31:458A, 1983.

    Google Scholar 

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© 1987 Martinus Nijhoff Publishing, Boston

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Marino, P.N., Weiss, J.L. (1987). Use of the Echocardiogram for Identifying Infarct Expansion. In: Califf, R.M., Wagner, G.S. (eds) Acute Coronary Care 1987. Acute Coronary Care Updates, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2337-2_18

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  • DOI: https://doi.org/10.1007/978-1-4613-2337-2_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9435-1

  • Online ISBN: 978-1-4613-2337-2

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