Abstract
The modern methods of molecular biology have led to major discoveries on the fine structure of eukaryotic genes and their expression in various biological situations. Comparatively, the progress in the definition of the replication units of eukaryotic DNA has been very slow; one has to deal with a periodic phenomenon restricted to a short period of the cell cycle. Moreover, eukaryotic cellular genomes are replicated as a series of several thousand replicons, so the replication of a specific DNA fragment is a short-lived event, which cannot be analyzed in nonsynchronously growing cultures of cells.
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Braun, R., Mittermayer, C., and Rusch, H. P., 1965, Sequential temporal replication of DNA in Physarum polycephalum, Proc. Natl. Acad. Sci., U.S.A., 53: 924.
Braun, R., and Ruedi-Wili, H., 1971, Early replicating DNA of Physarum is denser than late replicating DNA, Experientia, 27: 1412.
Braun, R., and Wili, H., 1969, Time sequence of DNA replication in Physarum, Biochim. Biophys. Acta, 174: 246.
Calza, R. E., Eckhardt, L. A., Delguidice, T., and Schildkraut, C. L., 1984, Changes in gene position are accompanied by a change in time of replication, Cell, 36: 689.
Daniel, J. W., and Baldwin, H. H., 1964, Methods of culture for plasmodial myxomycetes, in: “Methods in Cell Physiology”, Vol. 1, p. 9, D. M. Prescott, ed., Academic Press, New York.
Fouquet, H., Bohme, R., Wick, R., Sauer, H. W., and Scheller, K., 1975, Sane evidence for replication-transcription coupling in Physarum polycephalum, J. Cell Sci ., 18: 27.
Fouquet, H., and Sauer, H. W., 1975, Variable redundancy in RNA transcripts isolated in S and G2 phase of the cell cycle of Physarum, Nature, London, 255: 253.
Funderud, S., Andreassen, R., and Haugli, F., 1978a, DNA replication, in Physarum polycephalum: bidirectional replication of DNA within replicons, Nucl. Acids Res ., 5: 713.
Funderud, S., Andreassen, R., and Haugli, F., 1978b, Size distribution and maturation of newly replicated DNA through the S and G2 phases of Physarum polycephalum, Cell, 15: 1519.
Funderud, S., Andreassen, R., and Haugli, F., 1979, DNA replication in Physarum polycephalum: electron microscopic and autoradiographic analysis of replicating DNA from defined stages of the S period, Nucl. Acids Res ., 6: 1417.
Funderud, S., and Haugli, F., 1975, DNA replication in Physarum polycephalum: characterization of replication products in vivo, Nucl. Acids Res ., 2: 1381.
Goldman, M. A., Holmquist, G. P., Gray, M. C., Caston, L. A., and Nag, A., 1984, Replication timing of genes and middle repetitive sequences, Science, 224: 686.
Gorman, J. A., Dove, W. F., and Warren, N., 1981, Isolation of Physarum DNA segments that support autonomous replication in yeast, Mol. Gen. Genet ., 183: 306.
Hunt, B., and Vogelstein, B., 1981, Association of newly replicated DNA with the nuclear matrix of Physarum polycephalum, Nucl. Acids Res ., 9: 348.
Jalouzot, R., Toublan B., Wilhelm, M. L., and Wilhelm, F. X., 1985, Replication timing of the H4 histone genes in Physarum polycephalum, Proc. Natl. Acad. Sci., U.S.A., 82:6475.
Kubbies, M., and Pierron, G., 1983, Mitotic cell cycle control in Physarum, Exp. Cell Res ., 149: 57.
Mechali, M., and Kearsey, S., 1984, Lack of specific sequence requirement for DNA replication in Xenopus eggs compared with high sequence specificity in yeast, Cell, 38:55,
Mohberg, J., and Rusch, H. P., 1969, Growth of large Plasmodia of the myxomycete Physarum polycephalum, J. Bacteriol ., 97: 1411.
Nader, W. F., Edlind, T. D., Huettermann, A., and Sauer, H. W., 1985, Cloning of Physarum actin sequences in an exonucleus-deficient bacterial host, Proc. Natl. Acad. Sci., U.S.A ., 82: 2698.
Nygaard, O. F., Guttes, S., and Rusch, H. P., 1960, Nucleic acid metabolism in a slime mold with synchronous mitosis, Biochim. Biophys. Acta, 38: 298.
Pierron, G., Durica, D. S., and Sauer, H. W., 1984, Invariant temporal order of replication of the four actin gene loci during the naturally synchronous mitotic cycles of Physarum polycephalum, Proc. Natl. Acad. Sci., U.S.A ., 81: 6393.
Pierron, G., and Sauer, H. W., 1980, More evidence for replication transcription coupling in Physarum polycephalum, J. Cell Sci ., 41: 105.
Pierron, G., Sauer, H. W., Toublan, B., and Jalouzot, R., 1982, Physical relationship between replicons and transcription units in Physarum polycephalum, Eur, J. Cell Biol, 29: 104.
Rao, B.R and Gontcharoff, M., 1969, Functionality of newly synthesized DNA as related to RNA synthesis during mitotic cycle in Physarum polycephalum, Exp. Cell Res., 56: 269.
Rusch, H. P., 1980, The search, in: “Growth and Differentiation in Physarum polycephalum”, p. 1, W. F. Dove and H. P. Rusch, eds., Princeton University Press, Princeton.
Sauer, H. W., 1978, Regulation of gene expression in the cell cycle of Physarum polycephalum, in: “Cell Cycle Regulation”, p. 149, J. Jeter, I. L. Cameron, G. M. Padilla, and A. M. Zimmermann, eds., Academic Press, New York.
Schedl, T., Burland, T. G., Gull, K., and Dove, W. F., 1984, Cell cycle regulation of tubulin RNA level, tubulin protein synthesis, and assembly of microtubules in Physarum, J. Cell Biol ., 99: 155.
Schedl, T., and Dove, W. F., 1982, Mendelian analysis of the organization of actin sequences in Physarum polycephalum, J. Mol. Biol ., 160: 41.
Smithies, O., 1982, The control of globin and other eukaryotic genes, J. Cell Physiol., Suppl. 1: 137.
Stambrook, P. J., and Flickinger, R. A., 1970, Changes in chromosomal DNA replication patterns in developing frog embryos, J. Exp. Zool ., 174: 101.
Stinchcomb, D. T., Struhl, K., and Davis, R. W. 1979, Isolation and characterization of a yeast chromosomal replicator, Nature 282: 39.
Taylor, J. H., 1984, Origins of replication and gene regulation, Mol. Cell. Biochem ., 61: 99.
Vogt, V. M., and Braun, R., 1977, The replication of ribosomal DNA in Physarum polycephalum, Eur. J. Biochem ., 80: 557.
Waqar, M. A., and Huberman, J. A., 1975, Covalent linkage between RNA and nascent DNA in the slime mold Physarum polycephalum, Biochim. Biophys. Acta, 383: 410.
Wilhelm, M. L., Toublan, B., Jalouzot, R., and Wilhelm, F. X., 1984, Histone H4 gene is transcribed in S phase but also in late G2 phase in Physarum polycephalum, EMBO J ., 3: 2659.
Wilkins, A. S., 1976, Replicative patterning and determination, Differentiation, 5: 15.
Weintraub, H., Flint, S. J., Leffak, I. M., Groudine, M., and Grainger, R. M., 1978, The generation and propagation of variegated chromosome structures, Cold Spring Harbor Symp. Quant. Biol ., 42: 401.
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© 1986 Plenum Press, New York
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Pierron, G. (1986). Temporal Order of Replication and Gene Expression in Physarum polycephalum . In: Dove, W.F., Dee, J., Hatano, S., Haugli, F.B., Wohlfarth-Bottermann, KE. (eds) The Molecular Biology of Physarum polycephalum . NATO ASI Series, vol 106. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2203-0_4
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DOI: https://doi.org/10.1007/978-1-4613-2203-0_4
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