Skip to main content
SpringerLink
Log in

Structure of Rabies Virus

  • Chapter
Rabies

Part of the book series: Developments in Veterinary Virology ((DVVI,volume 7))

Abstract

Rabies virus possesses an unsegmented negative strand RNA genome. From a systematic point of view, all viruses presenting this particular genomic structure are grouped in 2 viral families, the Paramyxoviridae and the Rhabdoviridae (1). The host range of the Rhabdoviridae is surprisingly wide, extending from insects, with the sigma virus of Drosophila, to fishes and mammals (1). It is divided into 2 main genera, Vesiculovirus and Lyssavirus. The genus Vesiculovirus is comprised essentially of vesicular stomatitis virus (VSV) and its subtypes, and related viruses such as Chandipura and Piry. VSV is by far the best studied unsegmented negative strand RNA virus and has provided the basis for the majority of data accumulated concerning the viral architecture, mode of replication, and structural and functional studies (for a review see ref. 2). VSV is therefore a model for this group of viruses and will be referred to frequently in this chapter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 3rd Report of the International Committee on Taxonomy of Viruses, Intervirology 12: N°3–5, 1979.

    Google Scholar 

  2. Banerjee, A.K. Microbiol. Rev. 51: 66–87, 1987.

    PubMed  CAS  Google Scholar 

  3. Foggin, C.M. and Swanepoel, R. In: World’s Debt to Pasteur (Eds. H. Koprowski and S.A. Plotkin), The Wistar Symposium Series, vol. 3, Alan R. Liss, New York, 1985, pp. 219–234.

    Google Scholar 

  4. Schneider, L.G. Comp. Immun. Microbiol. Infect. Dis. 5: 101–107, 1982.

    CAS  Google Scholar 

  5. Koprowski, H., Wiktor, T.J. and Abelseth, M.K. In: Rabies in the Tropics (Eds. E. Kuwert, C. Mérieux, H. Koprowski and K. Bögel), Springer Verlag, Berlin, 1985, pp. 30–39.

    Google Scholar 

  6. Lafon, M., Bourhy, H. and Sureau, P. Vaccine, in press, 1987.

    Google Scholar 

  7. Pasteur, L. Semaine Médicale IV: 318–320, 1884.

    Google Scholar 

  8. Clark, H.F. and Wiktor, T.J. In: Strains of Human Viruses (Eds. M. Majer and S.A. Plotkin), Karger, Basel, 1972, pp. 177–182.

    Google Scholar 

  9. Week, P.K. and Wagner, R.R. J. Virol. 30: 410–413, 1979.

    Google Scholar 

  10. Tuffereau, C. and Martinet-Edelist, C. C.R. Acad. Sci. 300: 597–600, 1985.

    CAS  Google Scholar 

  11. Ermine, A. and Flamand A. Ann. Microbiol. 128: 477–488, 1977.

    Google Scholar 

  12. Flamand, A., Pese, D. and Bussereau, F. Virology 78: 323–327, 1977.

    PubMed  CAS  Google Scholar 

  13. Tordo, N., Poch, O., Ermine, A. and Keith, G. Nucleic Acids Res. 14: 2671–2683, 1986.

    PubMed  CAS  Google Scholar 

  14. Tordo, N., Poch, O., Ermine, A., Keith, G. and Rougeon, F. Proc. Natl. Acad. Sci. USA 83: 3914–3918, 1986.

    PubMed  CAS  Google Scholar 

  15. Tordo, N., Poch, O., Ermine, A., Keith, G. and Rougeon, F. in preparation, 1987.

    Google Scholar 

  16. Reagan, R.L. and Brueckner, A.L. J. Infect. Dis. 87: 213–216, 1950.

    PubMed  CAS  Google Scholar 

  17. Hottle, G.A., Morgan, C, Peers, J.H. and Wyckoff, R.W.G. Proc. Soc. Exptl. Biol. Med. 77: 721–725, 1951.

    CAS  Google Scholar 

  18. Lépine, P. and Croissant, O. Ann. Inst. Pasteur 81: 1–8, 1951.

    Google Scholar 

  19. Croissant, O., Lépine, P. and Wyckoff, R.W.G. Ann. Inst. Pasteur 89: 183–193 1955.

    CAS  Google Scholar 

  20. Roots, E. Z. Naturforsch. 17: 156–158, 1962.

    Google Scholar 

  21. Matsumoto, S. Virology 17: 198–202, 1962.

    PubMed  CAS  Google Scholar 

  22. Davies, M.C., Englert, M.E., Sharpless, G.R. and Cabasso V.J. Virology 21: 642–651, 1963.

    PubMed  CAS  Google Scholar 

  23. Atanasiu, P., Lépine, P., Sisman, J., Dauguet, C. and Wetten, M. C.R. Acad. Sci. 256: 3219–3221, 1963.

    Google Scholar 

  24. Murphy, F.A. In: The Natural History of Rabies, vol. 1 (Ed. G.M. Baer), Academic Press, New York, 1975, pp. 33–61.

    Google Scholar 

  25. Wunner, W.H. and Clark, H.F. J. Gen. Virol. 51: 69–81, 1980.

    PubMed  CAS  Google Scholar 

  26. Clark, H.F., Parks, N.F. and Wunner, W.H. J. Gen. Virol. 52: 245–258, 1980.

    Google Scholar 

  27. Lazzarini, R.A., Keene, J.D. and Schubert, M. Cell 26: 145–154, 1981.

    PubMed  CAS  Google Scholar 

  28. Blumberg, B.N. and Kolakofsky, D. J. Gen. Virol. 64: 1839–1847, 1983.

    PubMed  CAS  Google Scholar 

  29. Delagneau, J.F., Perrin, P. and Atanasiu, P. Ann. Virol. 132: 473–493, 1981.

    Google Scholar 

  30. Sokol, F., Stancek, D. and Koprowski, H. J. Virol. 7: 241–249, 1971.

    PubMed  CAS  Google Scholar 

  31. Dietzschold, B. J. Virol. 23: 286–293, 1977.

    PubMed  CAS  Google Scholar 

  32. Perrin, P. and Atanasiu, P. Microbiologica 3: 57–74, 1980.

    CAS  Google Scholar 

  33. Dietzschold, B., Cox, J.H., Schneider, L.G., Wiktor, T.J. and Koprowski, H. J. Gen. Virol. 40: 131–139, 1978.

    PubMed  CAS  Google Scholar 

  34. Wiktor, T.J., György, E., Schlumberger, H.D., Sokol, F. and Koprowski, H. J. Immunol. 110: 269–276, 1973.

    PubMed  CAS  Google Scholar 

  35. Perrin, P. and Atanasiu, P. Microbiologica 4: 231–247, 1981.

    CAS  Google Scholar 

  36. Zaides, V.M., Krotova, L.I., Selimova, L.M., Selimov M.A., Elbert, L.B. and Zhdanov, V.M. J. Virol. 29: 1226–1228, 1979.

    PubMed  CAS  Google Scholar 

  37. Cox, J.H., Weiland, F., Dietzschold, B. and Schneider, L.G. In: The Replication of Negative Strand Viruses (Eds. D.H.L Bishop and R.W. Compans), Elsevier/North-Holland, New York, 1981, pp. 639–645.

    Google Scholar 

  38. Kawai, A. J. Virol. 24: 826–835, 1977.

    PubMed  CAS  Google Scholar 

  39. Flamand, A., Delagneau, J.F. and Bussereau, F. J. Gen. Virol. 40: 233–238, 1978.

    PubMed  CAS  Google Scholar 

  40. Sokol, F., Schlumberger, H.D., Wiktor, T.J., Koprowski, H. and Hummeler, K. Virology 38: 651–665, 1969.

    PubMed  CAS  Google Scholar 

  41. Thomas, D., Newcomb, W.W., Brown, J.C., Wall, J.S., Hainfeld, J.F., Trus, B.L. and Steven, A.C. J. Virol. 54: 598–607, 1985.

    PubMed  CAS  Google Scholar 

  42. Madore, H.P. and England, J.M. J. Virol. 22: 102–112, 1977.

    PubMed  CAS  Google Scholar 

  43. Coslett, G.D., Holloway, B.P. and Obijeski, J.F. J. Gen. Virol. 49: 161–180, 1980.

    PubMed  CAS  Google Scholar 

  44. Dietzschold, B., Wiktor, T.J., Wunner, W.H. and Varrichio, A. Virology 124: 330–337, 1983.

    PubMed  CAS  Google Scholar 

  45. Sokol, F. and Clark, H.F. Virology 52: 246–263, 1973.

    Google Scholar 

  46. Sokol, F. and Clark, H.F. In: Negative Strand Viruses, vol. 1 (Eds. B.W.J. Mahy and R.D. Barry), Academic Press, London, 1975, pp. 25–50.

    Google Scholar 

  47. Tuffereau, C, Fischer S. and Flamand, A. J. Gen. Virol. 66: 2285–2289, 1985.

    PubMed  CAS  Google Scholar 

  48. Bishop, D.H.L. and Flamand, A In: Control Processes in Virus Multiplication (Eds. D.C. Burke and W.C. Russell), Cambridge University Press, 1975, pp. 95–152.

    Google Scholar 

  49. Flamand, A. and Delagneau, J.F. J. Virol. 28: 518–523, 1978.

    PubMed  CAS  Google Scholar 

  50. Kurilla, M.G., Cabridilla, CD., Holloway, B.P. and Keene, J.D. J. Virol. 50: 773–778, 1984.

    PubMed  CAS  Google Scholar 

  51. Holloway, B.P. and Obijeski, J.F. J. Gen. Virol. 49: 181–195, 1980.

    PubMed  CAS  Google Scholar 

  52. Pennica, D., Holloway, B.P., Heyward, J.T. and Obijeski, J.F. Virology 103: 517–521, 1980.

    PubMed  CAS  Google Scholar 

  53. Wunner, W.H., Curtis, P.J. and Wiktor, T.J. J. Virol. 36: 33–142, 1980.

    Google Scholar 

  54. Ball, L.A. and Wertz, G.W. Cell 26: 143–144, 1981.

    PubMed  CAS  Google Scholar 

  55. Rose, J.K. Cell 19: 415–421, 1980.

    PubMed  CAS  Google Scholar 

  56. Gupta, K.C. and Kingsbury, D.W. Nucleic Acids Res. 12: 3829–3841, 1984.

    Google Scholar 

  57. Collins, P.L., Dickens, L.E., Buckler-White, A., Olmsted, R.A., Spriggs, M.K., Camargo, E. and Coelingh, K.V.W. Proc. Natl. Acad. Sci. USA 83: 4594–4598, 1986.

    PubMed  CAS  Google Scholar 

  58. Ball, L.A. and White, C.N. Proc. Natl. Acad. Sci. USA 73: 442–446, 1976.

    PubMed  CAS  Google Scholar 

  59. Abraham, G. and Banerjee, A.K. Proc. Natl. Acad. Sci. USA 73: 1504–1508, 1976.

    PubMed  CAS  Google Scholar 

  60. Villareal, L.P., Breindl, M. and Holland, J.J. Biochemistry 15: 1663–1667, 1976.

    Google Scholar 

  61. Iverson, L.E. and Rose, J.K. Cell 23: 477–484, 1981.

    PubMed  CAS  Google Scholar 

  62. Pennica, D., Lynch, K.R., Cohen, P.S. and Ennis, H.L. Virology 94; 484–487, 1979.

    PubMed  CAS  Google Scholar 

  63. Weck, P.K., Carroll, A.R., Shattuck, D.M. and Wagner, R.R. J. Virol. 30: 746–753, 1979.

    CAS  Google Scholar 

  64. Weck, P.K. and Wagner, R.R. J. Biol. Chem. 254: 5430–5434, 1979.

    PubMed  CAS  Google Scholar 

  65. McGowan, J.J., Emerson, S.U. and Wagner, R.R. Cell 28: 325–333, 1982.

    PubMed  CAS  Google Scholar 

  66. Kurilla, M.G., Piwnica-Worms, H. and Keene, J.D. Proc. Natl. Acad. Sci. USA 79: 5240–5244, 1982.

    PubMed  CAS  Google Scholar 

  67. Dunigan, D.D., Baird, S. and Lucas-Lenard, J. Virology 150: 231–246, 1986.

    PubMed  CAS  Google Scholar 

  68. Grinnell, B.W. and Wagner, R.R. Cell 36: 533–543, 1984.

    PubMed  CAS  Google Scholar 

  69. Wilusz, J. and Keene, J.D. Virology 135: 65–73, 1984.

    PubMed  CAS  Google Scholar 

  70. Grinnell, B.W. and Wagner, R.R. Mol. Cell. Biol. 5: 2502–2513, 1985.

    PubMed  CAS  Google Scholar 

  71. Kurilla, M.G. and Keene, J.D. Cell 34: 837–845, 1983.

    PubMed  CAS  Google Scholar 

  72. Blumberg, B.M., Leppert, M. and Kolakofsky, D. Cell 23: 837–845, 1981.

    PubMed  CAS  Google Scholar 

  73. Blumberg, B.M., Giorgi, C. and Kolakofsky, D. Cell 32: 559–567, 1983.

    PubMed  CAS  Google Scholar 

  74. Dietzschold, B., Lafon, M., Wang, H., Otvos, L., Celis, E., Wunner, W.H. and Koprowski, H. Virus Res. 8: 103–125, 1987.

    PubMed  CAS  Google Scholar 

  75. Lafon, M. and Lafage, M. J. Gen. Virol. 68: in press, 1987.

    Google Scholar 

  76. Perrault, J., Clinton, G.M. and McClure, M.A. Cell 35: 175–185, 1983.

    PubMed  CAS  Google Scholar 

  77. Arnheiter, H., Davis, N.L., Wertz, G.W., Schubert, M. and Lazzarini, R.A. Cell 41: 259–267, 1985.

    PubMed  CAS  Google Scholar 

  78. Davis, N.L., Arnheiter, H. and Wertz, G.W. J. Virol. 59: 751–754, 1986.

    CAS  Google Scholar 

  79. Dietzschold, B., Wang, H., Rupprecht, C.E., Celis, E., Tollis, M., Ertl, H., Heber-Katz, E. and Koprowski, H. Proc. Natl. Acad. Sci. USA, in press, 1987.

    Google Scholar 

  80. Masters, P.S. and Banerjee, A.K. Virology 157: 298–306, 1987.

    PubMed  CAS  Google Scholar 

  81. Dietzschold, B., Cox, J.H. and Schneider, L.G. Virology 98: 63–75, 1979.

    PubMed  CAS  Google Scholar 

  82. Giorgi, C, Blumberg, B.M. and Kolakofsky, D. Cell 35: 829–836, 1983.

    PubMed  CAS  Google Scholar 

  83. Bellini, W.J., Englund, G., Rozenblatt, S., Arnheiter, H. and Richardson, C.D. J. Virol. 53: 908–919, 1985.

    PubMed  CAS  Google Scholar 

  84. Hudson, L.D., Condra, C. and Lazzarini, R.A. J. Gen. Virol. 67: 1571–1579, 1986.

    PubMed  CAS  Google Scholar 

  85. Poch, O., Tordo, N. and Keith, G. Biochimie, in press, 1987.

    Google Scholar 

  86. Clinton, G.M., Little, S.P., Hagen, F.S. and Huang, A.S. Cell 15: 1455–1462, 1978.

    PubMed  CAS  Google Scholar 

  87. De, B.P., Thornton, G.B., Luk, D. and Banerjee, A.K. Proc. Natl. Acad. Sci. USA 79: 7137–7141, 1982.

    PubMed  CAS  Google Scholar 

  88. Ogden, J.R., Pal, R. and Wagner, R.R. J. Virol. 58: 860–868, 1986.

    PubMed  CAS  Google Scholar 

  89. Zakowski, J.J. and Wagner, R.R. J. Virol. 36: 93–102, 1980.

    PubMed  CAS  Google Scholar 

  90. Capone, J. and Ghosh, H.P. Can. J. Biochem. Cell Biol. 62: 1174–1180, 1984.

    PubMed  CAS  Google Scholar 

  91. Newcomb, W.W., Tobin, G.J., McGowan, J.J. and Brown, J.C. J. Virol. 41: 1055–1062, 1982.

    PubMed  CAS  Google Scholar 

  92. Reidler, J.A., Keller, P.M., Elson, E.L., and Lenard, J. Biochemistry 20: 1345–1349, 1981.

    PubMed  CAS  Google Scholar 

  93. Kyte, J. and Doolittle, R.F. J. Mol. Biol. 157: 105–132, 1982.

    PubMed  CAS  Google Scholar 

  94. Wiktor, T.J., Macfarlan, R.I., Dietzschold, B., Rupprecht, C. and Wunner, W.H. Ann. Virol. 136: 405–411, 1985.

    Google Scholar 

  95. Dietzschold, B., Wiktor, T.J., Macfarlan, R.I. and Varrichio, A. J. Virol. 44: 595–602, 1982.

    PubMed  CAS  Google Scholar 

  96. Dietzschold, B., Wunner, W.H., Wiktor, T.J., Lopes, A.D., Lafon, M., Smith, C.L. and Koprowski, H. Proc. Natl. Acad. Sci. USA 80: 70–74, 1983.

    PubMed  CAS  Google Scholar 

  97. Lafon, M., Wiktor, T.J. and Macfarlan, R.I. J. Gen. Virol. 64: 843–851, 1983.

    PubMed  Google Scholar 

  98. Wunner, W.H., Smith, C.L., Lafon, M., Ideler, J. and Wiktor, T.J. In: Nonsegmented Negative Strand Viruses (Eds. D.H.L. Bishop and R.W. Compans), Academic Press, Orlando, 1984, pp. 279–284.

    Google Scholar 

  99. Macfarlan, R.I., Dietzschold, B., Wiktor, T.J., Kiel, M., Hough-ten, R., Lerner, R.A., Sutcliffe, J.G. and Koprowski, H. J. Immunol. 133: 2748–2752, 1984.

    PubMed  CAS  Google Scholar 

  100. Macfarlan, R.I., Dietzschold, B. and Koprowski, H. Mol. Immunol. 23: 733–741, 1986.

    PubMed  CAS  Google Scholar 

  101. Perrin, P., Portnoï, D. and Sureau, P. Ann. Virol. 133: 403–422, 1982.

    Google Scholar 

  102. Anilionis, A., Wunner, W.H. and Curtis, P.J. Nature (Lond.) 294: 275–278, 1981.

    CAS  Google Scholar 

  103. Malek, L.T., Sootsmeyer, G., Garvin, R.T. and James, E. In: Modern Approaches to Vaccines (Eds. R.M. Chanock and R.A. Lerner), Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1984, pp. 203–208.

    Google Scholar 

  104. Yelverton, E., Norton, S., Obijeski, J.F. and Goeddel, D.V. Science 219: 614–620, 1983.

    PubMed  CAS  Google Scholar 

  105. Lai, C.Y. and Dietzschold, B. Biochem. Biophys. Res. Commun. 103: 536–542, 1981.

    PubMed  CAS  Google Scholar 

  106. Dietzschold, B., Wunner, W.H., Lafon, M., Smith, C.L. and Varrichio, A In: Nonsegmented Negative Strand Viruses (Eds. D.H.L. Bishop and R.W. Compans), Academic Press, Orlando, 1984, pp. 285–293.

    Google Scholar 

  107. Wunner, W.H., Dietzschold, B., Smith, C.L., Lafon, M. and Gotlub, E. Virology 140: 1–12, 1985.

    PubMed  CAS  Google Scholar 

  108. Schubert, M., Harminson, G.G. and Meier, E. J. Virol. 51: 505–514, 1984.

    PubMed  CAS  Google Scholar 

  109. Shioda, T., Iwasaki, K. and Shibuta, H. Nucleic Acids Res. 14: 1545–1563, 1986.

    PubMed  CAS  Google Scholar 

  110. Yusoff, K., Millar, N.S., Chambers, P. and Emmerson, P.T. Nucleic Acids Res. 15: 3961–3976, 1987.

    PubMed  CAS  Google Scholar 

  111. Banerjee, A.K., Moyer, S.A. and Rhodes, D. Virology 61: 547–558, 1974.

    PubMed  CAS  Google Scholar 

  112. Keene, J.D., Schubert, M. and Lazzarini, R.A. J. Virol. 32: 167–174, 1979.

    PubMed  CAS  Google Scholar 

  113. Nichol, S.T. and Holland, J.J. J. Virol. 61: 200–205, 1987.

    PubMed  CAS  Google Scholar 

  114. Keene, J.D., Thornton, B.J. and Emerson, S.U. Proc. Natl. Acad. Sci. USA 78: 6191–6195, 1981.

    PubMed  CAS  Google Scholar 

  115. Isaac, C.L. and Keene, J.D. J. Virol. 43: 241–249, 1982.

    PubMed  CAS  Google Scholar 

  116. Rayssiguier, C, Cioe, L., Withers, E., Wunner, W.H. and Curtis, P.J. Virus Res. 5: 177–190, 1986.

    PubMed  CAS  Google Scholar 

  117. Kurath, G. and Leong, J.C. J. Virol. 53: 462–468, 1985.

    PubMed  CAS  Google Scholar 

  118. Kurath, G., Ahern, K.G., Pearson, G.D. and Leong, J.C. J. Virol. 53: 469–476, 1985.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Unité de la Rage, Institut Pasteur, 25 rue du Docteur Roux, 75724, Paris, France

    Noel Tordo

  2. Groupe Biochimie II, Institut de Biologie Moléculaire et Cellulaire du C.N.R.S., 15 rue Descartes, 67084, Strasbourg, France

    Olivier Poch

Authors
  1. Noel Tordo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Olivier Poch
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Toronto, Toronto, Ontario, Canada

    James B. Campbell

  2. Animal Diseases Research Institute, Agriculture Canada, Nepean, Canada

    K. M. Charlton

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Kluwer Academic Publishers, Boston

About this chapter

Cite this chapter

Tordo, N., Poch, O. (1988). Structure of Rabies Virus. In: Campbell, J.B., Charlton, K.M. (eds) Rabies. Developments in Veterinary Virology, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1755-5_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-1755-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8985-2

  • Online ISBN: 978-1-4613-1755-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation