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Principles of Antiretroviral Therapy for AIDS and Related Diseases

  • Chapter
Clinical Use of Antiviral Drugs

Part of the book series: Developments in Medical Virology ((DIMV,volume 3))

Abstract

Every step in the life cycle of pathogenic human retroviruses could theoretically serve as a target for antiviral therapy. In particular, the process of reverse transcription appears to be an attractive target. A number of drugs and pharmacologic principles relevant to the administration of such drugs have been identified for application in the therapy of diseases mediated by pathogenic human retroviruses. One family of such drugs (2′,3′-dideoxynucleoside analogues) shows special promise. These drugs are now being administered to patients with AIDS and its related disorders.

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  1. J. Balzarini

    Present address: Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000, Leuven, Belgium

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  1. Clinical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA

    J. Balzarini & S. Broder

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    Erik De Clercq

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Balzarini, J., Broder, S. (1988). Principles of Antiretroviral Therapy for AIDS and Related Diseases. In: De Clercq, E. (eds) Clinical Use of Antiviral Drugs. Developments in Medical Virology, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1715-9_21

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  • DOI: https://doi.org/10.1007/978-1-4613-1715-9_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8966-1

  • Online ISBN: 978-1-4613-1715-9

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