Skip to main content

Part of the book series: Cancer Treatment and Research ((CTAR,volume 82))

Abstract

Intraperitoneal chemotherapy has been described as a therapeutic option in the management of a variety of malignancies that occur primarily in a locoregional manner [1]. Potential benefits of this technique may occur in tumors principally confined to the peritoneal cavity (gastrointestinal malignancies and ovarian carcinoma) [2,3]. Theoretically, the use of intraperitoneal drug could eliminate local tumor spread as a mechanism of cancer recurrence both in the abdomen and in the pelvis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Spratt JS, Edwards M, Kubota T, Lindberg R, Tseng MT. Peritoneal carcinomatosis: Anatomy, physiology, diagnosis and management. Curr Prol Cancer 1986;10:553–584.

    Article  Google Scholar 

  2. Sugarbaker PH, Cunliffe W, Belliveau J, et al. Rationale for early postoperative intraperitoneal chemotherapy as a surgical adjuvant for gastrointestinal malignancy. Reg Cancer Treat 1989;1:66–79.

    Google Scholar 

  3. Markman M, Howell SB, Lucas WE, Pfeifle CE, Green MR. Combination intraperitoneal chemotherapy with cisplatin, cytarabine, doxorubicin for refractoy ovarian carcinoma and other malignancies principally confiend to the peritoneal cavity. J Clin Oncol 1984;2: 1321–1325.

    PubMed  CAS  Google Scholar 

  4. Jacquet P, Vidal-Jove J, Zhu B, Sugarbaker PH. Peritoneal carcinomatosis from gastrointestinal malignacy: Natural history and new prospects for management. Acta Chir Belg 1994;94:191–197.

    PubMed  CAS  Google Scholar 

  5. Sugarbaker PH. Cytoreductive approach to peritoneal carcinomatosis: Peritonectomy and intraperitoneal chemotherapy. In Postgraduate Advances in Colorectal Surgery. Forum Medicum, 1991, II-X.

    Google Scholar 

  6. Esperanda MJ, Collins DL. Peritoneal dialysis efficiency in relaion to body weight. J Pediatr Sur 1966;1:162–169.

    Article  Google Scholar 

  7. Pfeiffer CJ, Pfeiffer DC, Misra HP. Enteric serosal surface in the piglet. A scanning and transmission electron microscopic study of the mesothelium. J Submicrosc Cytol 1987; 19: 237–246.

    PubMed  CAS  Google Scholar 

  8. Waiters WB, Buck RC. Scanning electron microscopy of mesothelial regeneration in the rat. Lab Invest 1972;26:604–609.

    Google Scholar 

  9. Kruger S, Greve DW, Schueler FW. Absorption of fluid from peritoneal cavity. Arch Int Pharmacodyn Ther 1962;137:173–178.

    PubMed  CAS  Google Scholar 

  10. Yoffey JM, Courtice FC. Lymphatics, Lymph and the Lymphomyeloid Complex. London: Academic Press, 1970;206–231.

    Google Scholar 

  11. Greenwalt D, Nakamura RM, diZerega G. Determination of pH and pKa in human peritoneal fluid. Curr Surg 1988;45:217–218.

    Google Scholar 

  12. Aune S. Transperitoneal exchange IV. The effect of transperitoneal fluid transport on the transfer of solutes. Scand J Gastroenterol 1970;5:241–252.

    PubMed  CAS  Google Scholar 

  13. Torres IG, Litterest CL, Guarino AM. Transport of model compounds across the peritoneal menbrane in the rat. Pharmacology 1987;17:330–340.

    Article  Google Scholar 

  14. Fedorko ME, Hirsch JG, Studies on transport of macromolecules and small particles across the mesothelial cells of the mouse omentum. I. Morphological aspects. Exp Cell Res 1971;69:113–127.

    Article  PubMed  CAS  Google Scholar 

  15. Lukas G, Brindle SD, Greengerd P. The route of absorption of intraperitoneally administered compounds. J Pharmacol Exp Ther 1971;178:562–566.

    PubMed  CAS  Google Scholar 

  16. Rippe B, Stelin G. Peritoneal transport of water and solutes. Proceedings of Peritoneum and Peritoneal Access. Lund: Sweden, 1987, p 41.

    Google Scholar 

  17. Arnaud JP, Adolf M. Physiopathologie du péritoine. Péritonisation-drainage. In Encycl Med Chir Techniques chirurgicales, Appareil digestif. Paris: 1989(11);40070: 15.

    Google Scholar 

  18. Leak LV, Rahil K. Permeability of the diaphragmatic mesothelium:the ultrastructural basis for stromata. Am J Anat 1978;151:557–594.

    Article  PubMed  CAS  Google Scholar 

  19. Lill SR, Parsons RH, Buchac I. Permeability of the diaphragma nd fluid resorption from the peritoneal cavity in the rat. Gastroenterology 1979;76:997–1002.

    PubMed  CAS  Google Scholar 

  20. Flessner ME, Fenstermacher JD, Blasberg RG, et al. Peritoneal absorption of macro-molecules studied by quantitative autoradiography. Am J Physiol 1985;248:26–32.

    Google Scholar 

  21. Sugarbaker PH, Cunliffe WJ, Belliveau J, de Cruijn EA, et al. Rationale for integrating early postoperative intraperitoneal chemotherapy into the surgical treatment of gastrointestinal cancer. Semin Oncol 1989;16:83–97.

    PubMed  CAS  Google Scholar 

  22. Gross ML, Somani P, Ribner BS, Raeader R, et al. Ceftizoxime elimination kinetics in continuous ambulatory peritoneal dialysis. Clin Pharmacol Ther 1983;34:673–680.

    Article  PubMed  CAS  Google Scholar 

  23. Keller E, Reetze, P, Schollmeyer P. Drug therapy in patients undergoing continuous ambulatory peritoneal dialysis. Clin Pharmacokinet 1900;18:104–117.

    Article  Google Scholar 

  24. Dedrick RL. Theoretical and experimental bases of intraperitoneal chemotherapy. Semin Oncol 1985;12:1–6.

    PubMed  CAS  Google Scholar 

  25. Flessner MF, Dedrick RL, Schultz JS. A distributed model of peritoneal-plasma transport: Analysis of experimental data in the rat. Am J Physiol 1985;248:F413-F424.

    PubMed  CAS  Google Scholar 

  26. Rubin J, Jones Q, Planch A, Bower JD. The minimal importance of the hollow viscera to peritoneal transport during peritoneal dialysis in the rat. Am Soc Artif Intern Organs Transact 1988;34:912–915.

    CAS  Google Scholar 

  27. Sugarbaker PH, Klecker RW, Gianola FJ, Speyer JL. Prolonged treatment schedules with intraperitoneal 5-fluorouracil diminish the loco-regional naure of drug distribution. Am J Clin Oncol 1986;9:1–7.

    Article  PubMed  CAS  Google Scholar 

  28. Sugarbaker PH, Stuart OA, Vidal-Jove J, Pessagno AM, DeBruijn EA. Studies of the peritonea-plasma barrier after systemic mitomycin C administration. Reg Cancer Treat 1993;4:188–194.

    Google Scholar 

  29. Maher JF. Physiology of the peritoneum. Implications for peritoneal dialysis. Med Clin North Am 1990;74(4):985–996.

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Kluwer Academic Publishers, Boston

About this chapter

Cite this chapter

Jacquet, P., Sugarbaker, P.H. (1996). Peritoneal-plasma barrier. In: Sugarbaker, P.H. (eds) Peritoneal Carcinomatosis: Principles of Management. Cancer Treatment and Research, vol 82. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1247-5_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-1247-5_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8531-1

  • Online ISBN: 978-1-4613-1247-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics