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Clinical Aspects of Cryptococcosis in Patients with AIDS

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Mycoses in AIDS Patients

Abstract

Cryptococcosis, generally presenting as meningitis, is the most life threatening fungal infection in patients with AIDS. Its prevalence varies from 5% in Western Europe to 20% in Tropical Africa. Besides this dramatically increased frequency, cryptococcosis in AIDS patients differs in several respects from the mycosis as observed in non-AIDS patients. The paucity of meningeal signs and the low cell count and protein level in the cerebrospinal fluid tend to delay the diagnosis. A high index of suspicion and systematic screening of all suspected HIV positive patients for serum cryptococcal antigen may detect the disease at an earlier stage and improve survival.

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Authors and Affiliations

  1. Dept. of Bacteriology, St-Raphael University Hospital, B-3000, Leuven, Belgium

    Jozef Vandepitte

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  1. Jozef Vandepitte
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Editors and Affiliations

  1. Janssen Research Foundation, Beerse, Belgium

    Hugo Vanden Bossche , Geert Cauwenbergh  & Jan Van Cutsem ,  & 

  2. Central Public Health Laboratory, London, UK

    Donald W. R. Mackenzie

  3. Institut Pasteur, Paris, France

    Edouard Drouhet  & Bertrand Dupont  & 

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© 1990 Plenum Press, New York

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Vandepitte, J. (1990). Clinical Aspects of Cryptococcosis in Patients with AIDS. In: Bossche, H.V., Mackenzie, D.W.R., Cauwenbergh, G., Van Cutsem, J., Drouhet, E., Dupont, B. (eds) Mycoses in AIDS Patients. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0655-9_10

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  • DOI: https://doi.org/10.1007/978-1-4613-0655-9_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7912-9

  • Online ISBN: 978-1-4613-0655-9

  • eBook Packages: Springer Book Archive

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