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Possible Implications of the Cellular Component of the Immune System in the Pathogenesis of Unconventional Slow Virus Infections

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Trends in Neuroimmunology

Abstract

A group of infectious degenerative disorders of the CNS naturally occurring in animals and man is referred as unconventional slow virus diseases although the etiological agent has yet to be definitively identified. The transmissibility of these disorders, their long latency period, the atypical properties of the infectious agent such as its resistance to nucleases,101 its inactivation only with high doses of UV59, or ionizing radiations2 and its peculiar structure devoid of a detectable nucleic acid, account for the definition given of unconventional slow virus diseases.48

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Authors and Affiliations

  1. Institute of General Pathology, Catholic University, Rome, Italy

    Patrizia Casaccia & Anna Ladogana

  2. Institute of Neurology, Catholic University, Rome, Italy

    Carlo Masullo & Giorgio Macchi

  3. Department of Biology, University of Lecee, Lecce, Italy

    Maurizio Pocchiari

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  1. Patrizia Casaccia
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  2. Anna Ladogana
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  3. Carlo Masullo
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  4. Giorgio Macchi
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  5. Maurizio Pocchiari
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  1. University of Cagliari, Cagliari, Italy

    Maria Giovanna Marrosu  & Carlo Cianchetti  & 

  2. University of Padua, Padua, Italy

    Bruno Tavolato

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© 1990 Plenum Press, New York

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Casaccia, P., Ladogana, A., Masullo, C., Macchi, G., Pocchiari, M. (1990). Possible Implications of the Cellular Component of the Immune System in the Pathogenesis of Unconventional Slow Virus Infections. In: Marrosu, M.G., Cianchetti, C., Tavolato, B. (eds) Trends in Neuroimmunology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0607-8_17

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  • DOI: https://doi.org/10.1007/978-1-4613-0607-8_17

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