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Selenium and Glutathione Peroxidase: Essential Nutrient and Antioxidant Component of the Immune System

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Antioxidant Nutrients and Immune Functions

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 262))

Abstract

Dioxygen (02) is required by most plants and animals (aerobes) for the oxidation of carbohydrates (glucose principally), protein (amino acids) and lipids (fatty acids) which serves as the terminal acceptor in mitochondria of both hydrogen and electrons in the formation of metabolic water. For aerobic metabolism dioxygen is essential. Other forms of life, the anaerobes, are viable only in the absence of dioxygen, for dioxygen is toxic to anaerobic organisms. Aerobic life has thus evolved in a dioxygen environment having developed the necessary cellular defenses to thwart dioxygen toxicity.

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Authors and Affiliations

  1. Texas Tech University, Institute for Nutritional Sciences and Center for Food and Nutrition, Lubbock, TX, 79409, USA

    Julian E. Spallholz

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  1. Julian E. Spallholz
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  1. Hoffmann LaRoche, Inc., Nutley, New Jersey, USA

    Adrianne Bendich

  2. Agricultural Research Service, USDA, NADC, Ames, Iowa, USA

    Marshall Phillips

  3. Colorado State University, Fort Collins, Colorado, USA

    Robert P. Tengerdy

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Spallholz, J.E. (1990). Selenium and Glutathione Peroxidase: Essential Nutrient and Antioxidant Component of the Immune System. In: Bendich, A., Phillips, M., Tengerdy, R.P. (eds) Antioxidant Nutrients and Immune Functions. Advances in Experimental Medicine and Biology, vol 262. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0553-8_12

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  • DOI: https://doi.org/10.1007/978-1-4613-0553-8_12

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