Abstract
The identity of cells in the atherosclerotic plaque has been much discussed in the older histological and ultrastructural literature. More recently histochemical techniques have been used to distinguish cells of the mononuclear phagocyte series from vascular smooth muscle. These techniques depend on the much greater oxidative and lysosomal enzyme activity in mononuclear cells than in vascular smooth muscle, e.g. catalase (Adams et al. 1975), cytochrome oxidase (Adams and Bayliss 1976a, b), acid esterase (Wolman and Gaton 1976; Gaton and Wolman 1977), acid lipase (Schaffner et al. 1977, 1978). In the present presentation it was shown that β-galactosidase gives superior results in identifying mononuclear phagocyte cells than the other methods mentioned above (see Bayliss-High and Adams 1980).
Supported in part by a grant from the British Heart Foundation.
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Adams, C.W.M., Bayliss-High, O.B. (1980). Mononuclear Phagocytes in Atherosclerosis. In: Gotto, A.M., Smith, L.C., Allen, B. (eds) Atherosclerosis V. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6071-4_26
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DOI: https://doi.org/10.1007/978-1-4612-6071-4_26
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