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The Pathology of Human Teratomas

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The Human Teratomas

Part of the book series: Contemporary Biomedicine ((CB,volume 3))

Abstract

Teratomas are tumors composed of multiple tissues foreign to the anatomic site from which they originate (Willis, 1951). The term, coined from the Greek words teras meaning monster, and the suffix -oma (from onkoma—swelling) to denote its neoplastic nature, was introduced by Virchow (1863), and since then, it has been used to describe both benign and malignant tumors composed of haphazardly intermixed tissues originating from actually or potentially pluripotent stem cells. Teratomas are considered to be neoplasms because of their progressive, uncoordinated and unregulated growth. The teratoid, ie., monster-like appearance of these tumors, reflects abnormal development of tissues originating from the pluripotent stem cells. Since teratomas represent true neoplasms, most of them are unrelated to congenital malformations or abnormal embryonic development (Warkany, 1971).

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  1. Department of Pathology, Hahnemann Medical College and Hospital, Philadelphia, Pennsylvania, USA

    Ivan Damjanov

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  1. Department of Pathology, Hahnemann Medical College and Hospital, Philadelphia, Pennsylvania, USA

    Ivan Damjanov

  2. The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA

    Davor Solter

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Damjanov, I. (1983). The Pathology of Human Teratomas. In: Damjanov, I., Knowles, B.B., Solter, D. (eds) The Human Teratomas. Contemporary Biomedicine, vol 3. Humana Press. https://doi.org/10.1007/978-1-4612-5628-1_2

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