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Heterogeneity of alpha-1 Adrenergic Receptors

  • Chapter
The alpha-1 Adrenergic Receptors

Part of the book series: The Receptors ((REC))

Abstract

The alpha-1 adrenergic receptor, located postjunctionally on smooth muscle and other tissues, has been studied for decades, although not recognized as a specific subtype. Until recently, alpha-adrenergic receptors were not subdivided, and the alpha-adrenergic receptor-mediated responses commonly measured, such as contraction of smooth muscle in vitro and elevation of blood pressure in the intact animal, resulted from activation of receptors now designated as alpha-1.

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Authors
  1. J. Paul Hieble
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  2. William D. Matthews
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  3. Robert M. DeMarinis
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  4. R. Robert Ruffolo Jr.
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Editors and Affiliations

  1. Smith Kline & French Laboratories, Swedeland, Pennsylvania, USA

    Robert R. Ruffolo Jr.

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Hieble, J.P., Matthews, W.D., DeMarinis, R.M., Ruffolo, R.R. (1987). Heterogeneity of alpha-1 Adrenergic Receptors. In: Ruffolo, R.R. (eds) The alpha-1 Adrenergic Receptors. The Receptors. Humana Press. https://doi.org/10.1007/978-1-4612-4582-7_8

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