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Regulation and Development of Muscarinic Receptor Number and Function

  • Chapter
The Muscarinic Receptors

Part of the book series: The Receptors ((REC))

Abstract

Knowledge of the factors involved in the regulation, development, expression, maintenance, localization, and function of neurotransmitter receptors is of obvious importance for understanding how signal processing in the nervous system may be controlled. The regulation of the number and action of muscarinic acetylcholine receptors (mAChR) present on cells and tissues is of interest both because of the fundamental neurobiological question of identifying the processes that determine the physiological sensitivity of a cell to cholinergic stimulation, as well as because of the possible therapeutic and pathological implications of changes in the mAChR. This chapter will summarize some of the studies carried out to identify the mechanisms that control the number and function of the mAChR.

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  1. Neil M. Nathanson
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  1. University of California, San Diego, La Jolla, California, USA

    Joan Heller Brown

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Nathanson, N.M. (1989). Regulation and Development of Muscarinic Receptor Number and Function. In: Brown, J.H. (eds) The Muscarinic Receptors. The Receptors. Humana Press. https://doi.org/10.1007/978-1-4612-4498-1_11

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  • DOI: https://doi.org/10.1007/978-1-4612-4498-1_11

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