Abstract
The role of the vasa vasorum in the pathophysiology of atherosclerotic coronary artery disease remains controversial. There is no doubt that these small vessels of the arterial wall exist in far greater numbers in regions associated with plaque. Observations made as early as 1876 and confirmed in 1938 have firmly established this association (1,2). In recent times, most authors pay little attention to the vasa vasorum in their focus on the lipid constituents of the plaque. On the other hand, some have proposed a fundamental role for the vasa vasorum in the progression of the lesion (3,4). Within the context of the present symposium, the issue which seems to call for particular attention is the contribution of the vasa vasorum to plaque hemorrhage and the formation of lumenal thrombus.
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Beeuwkes, R., Barger, A.C., Silverman, K.J., Lainey, L.L. (1990). Cinemicrographic Studies of the Vasa Vasorum of Human Coronary Arteries. In: Glagov, S., Newman, W.P., Schaffer, S.A. (eds) Pathobiology of the Human Atherosclerotic Plaque. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3326-8_28
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DOI: https://doi.org/10.1007/978-1-4612-3326-8_28
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