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Organochlorine Pesticides and Polychlorinated Biphenyls in Human Adipose Tissue*

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Reviews of Environmental Contamination and Toxicology

Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 120))

Abstract

The U.S. Environmental Protection Agency (U.S. EPA) has estimated that approximately 750,000 chemicals are now in use in homes, industry, and agriculture. This does not include pesticides, pharmaceuticals, and food additives, nor the estimated 1,500 different ingredients used in pesticides (Geyer et al. 1986).

Although funded by the U.S. Environmental Protection Agency through Contract Nos. 68-02-4254 and 68-D9-0166 to Versar Inc., this contribution has not been subjected to Agency review and therefore does not necessarily reflect the views of the Agency and no official endorsement should be inferred.

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References

  • Abbott DC, Collins GB, Goulding R (1972) Organochlorine pesticide residues in human fat in the United Kingdom, 1969–71. Birt Med J 2: 553–556.

    CAS  Google Scholar 

  • Abbott DC, Collins GB, Goulding R, Hoodies RA (1981) Organochlorine pesticide residues in human fat in the United Kingdom, 1976–77. Brit Med J 283: 1425–1428.

    CAS  Google Scholar 

  • Ackerman LB (1980) Humans overview of human exposure to dieldrin residues in the environment and current trends of residue levels in tissue. Pestic Monit J 14: 64–69.

    PubMed  CAS  Google Scholar 

  • Adeshina F, Todd E (1989) Organochlorine compounds in human adipose tissue from North Texas. J Toxicol Environ Hlth 00: 000–000.

    Google Scholar 

  • Aizicovici H, Cocisiu M, Nistor C. Unterman WH (1974) Pollution of food by organochlorine insecticides and impregnation of human body with these pesticides in some regions of Rumania. Environmental Quality and Safety, Supplement Vol III. Pesticides, Lectures held at IUAC 3rd Intl Cong of Pesticide Chem Helsinki, pp 852–854.

    Google Scholar 

  • Albert L, Mendez F (1980) Organochlorine pesticide residues in human adipose tissue in Mexico: results of a preliminary study in three Mexican cities. Arch Environ Hlth 35 (5): 262–269.

    CAS  Google Scholar 

  • Ansari GA, James GP, Hu LA, Reynolds ES (1986) Organochlorine residues in adipose tissue of residents of the Texas Gulf Coast. Bull Environ Contam Toxicol 36: 311–316.

    PubMed  CAS  Google Scholar 

  • Barquero M, Constenla M (1986) Organochlorine pesticide residues in the adipose tissue of Costa Rican farmers. Turrialba 36 (2): 191–96.

    CAS  Google Scholar 

  • Barquet A, Morgade C, Pfaffenberger CD (1981) Determination of organochlorine pesticides and metabolites in drinking water, human blood serum, nd adipose tissue. J Toxicol Environ Hlth 7: 469–479.

    CAS  Google Scholar 

  • Bertram HP, Kemper FH, Muller C (1986) Hexachlorobenzene content in human whole blood and adipose tissue: experiences in environmental specimen banking. In: Morris CR, Cabral JRP (eds) Hexachlorobenzene: Proceedings of an International Symposium, Lyon, France, 24–28 June 1985. IARC Publication No. 77. Oxford University Press, New York pp 173–182.

    Google Scholar 

  • Bhaskaran M, Sharma RC, Bhide NK (1979) DDT levels in human fat samples in Delhi area. Ind J Exp Biol 17: 1390–1392.

    CAS  Google Scholar 

  • Biros FJ, Enos HF (1973) Oxychlordane residues in human adipose tissue. Bull Environ Contam Toxicol 5: 257–261.

    Google Scholar 

  • Biros FJ, Walker AC, Medbery A (1970) Polychlorinated biphenyls in human adipose tissue. Bull Environ Contam Toxicol 5: 317–323.

    CAS  Google Scholar 

  • Brady MN, Siyali DS (1972) Hexachlorobenzene in human body fat. Med J Aust 1: 158–160 (cited in Hayes 1982).

    Google Scholar 

  • Brevik EM, Bjerk JE (1978) Organochlorine compounds in Norwegian human fat and milk. Acta Pharmacol et Toxicol 43: 59–63.

    CAS  Google Scholar 

  • Brooks GT (1974) Chlorinated insecticides, Vol I and II. CRC Press, Cleveland, OH.

    Google Scholar 

  • Burns JE (1974) Organochlorine pesticide and polychlorinated biphenyl residues in biopsied human adipose tissue—Texas 1969–72. Pestic Monit J 7 (3–4): 122–26.

    Google Scholar 

  • Cantoni C, Cattaneo P, Fabbris F (1986) Presence of organochlorine pesticides in man in relation to food or animal origin. Ind Ailment 25 (6): 446–449.

    CAS  Google Scholar 

  • Casarett LJ, Fryer GC, Yauger WL, Klemmer HW (1968) Organochlorine pesticide and polychlorinated biphenyl residues in biopsied human adipose tissue—Hawaii. Arch Environ Hlth 17: 306–311.

    CAS  Google Scholar 

  • Curley A, Burse VW, Jennings RW, Villanueva EC, Tomatis L, Akazaki K (1973) Chlorinated hydrocarbon pesticides and related compounds in adipose tissue from people of Japan. Nature 242: 338–340.

    PubMed  CAS  Google Scholar 

  • Davies JE, Edmundson WF, Schneider NJ, Cassady JC (1968) Problems of prevalence of pesticide residues in humans. Pestic Monit J 2: 80–85.

    PubMed  CAS  Google Scholar 

  • Davies JE, Edmunson WF, Maceo A, Barquet A, Cassady J (1969) An epidemiologic application of the study of DDE levels in whole blood. Am J Pub Hlth 59 (3): 435–441.

    CAS  Google Scholar 

  • Dejonckheere W, Steubaut W, Verstraeten R, Kips RH (1978) Residues of organochlorine pesticides in human fat in Belgium. Toxicol Eur Res 1: 93–98.

    PubMed  CAS  Google Scholar 

  • Del Dot M, Stringari G, Avancini D (1978) Comparative investigation on chlorinated pesticides in human fat in the Province of Trento, Italy in the years 1969 and 1977. Ig Mod 71 (8): 980–988.

    Google Scholar 

  • Doguchi M, Ushio F, Niwayama K, Nishida K (1971) Pesticide content of human female fat in metropolitan area. Tokyo Toritsu Eisei Kentyusho Kenkya Nerpo (Ann Rept Tokyo Metro Res Lab Pub Hlth) 22: 131–133.

    Google Scholar 

  • Doguchi M (1977) Polychlorinated terphenyls as an environmental pollutant in Japan. Ecotox Environ Saf 1: 239–248.

    CAS  Google Scholar 

  • Durham WF (1969) Body burden of pesticides in man. Ann NY Acad Sci 160 (1): 183–195.

    PubMed  CAS  Google Scholar 

  • Dynamac (1987a) Toxicological profile for aldrin/dieldrin. Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Public Health Service, Washington, DC.

    Google Scholar 

  • Dynamac (1987b) Toxicological profile for heptachlor/heptachlor epoxide. Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Public Health Service, Washington, DC.

    Google Scholar 

  • Edmundson WF, Davies JE, Hull W (1968) Dieldrin storage levels in necropsy adipose tissue from a South Florida population. Pestic Monit J, 2: 86–89.

    PubMed  CAS  Google Scholar 

  • Fiserova-Bergerova V, Radomski JL, Davies JE, Davis JH (1967) Levels of chlorinated hydrocarbon pesticides in human tissues. Indus Med Surg: 65–70.

    Google Scholar 

  • Focardi S, Fossi C, Leonzio C, Romei R (1986) PCB congeners, hexachlorobenzene, and organochlorine insecticides in human fat in Italy. Bull Environ Contam Toxicol 36: 644–650.

    PubMed  CAS  Google Scholar 

  • Fournier E, Treich I, Capellc N, Campagnel (1972) Pesticides organochloroes don le tissu adipeux d/etros humains en France. Eur J Toxicol 5 (1): 11–26.

    PubMed  CAS  Google Scholar 

  • Fukano S, Doguchi M (1977) PCT, PCB, and pesticide residues in human fat and blood. Bull Environ Contam Toxicol 17 (5): 613–617.

    PubMed  CAS  Google Scholar 

  • Garcia Fernandez J (1971) Chlorinated pesticides in infant human fat in the Republic of Argentina. J Argentina Toxicol Anal, Aetas 1st Meeting, Vol 1. pp 106–130.

    Google Scholar 

  • Geyer H, Scheunert I, Korte F (1986) Bioconcentration potential of organic environmental chemicals in humans. Reg Toxicol Pharmacol 6: 313–347.

    CAS  Google Scholar 

  • Gopalaswamy UV, Aiyar A (1986) Biotransformation and toxicity of lindane and its metabolite hexachlorobenzene in mammals. In: Morris CR, Cabral JRP (eds) Hexachlorobenzene: Proceeding of an international symposium. Lyons, France, 24–25 June 1985. IARC Publication No. 77. Oxford University Press, New York, pp 267–276.

    Google Scholar 

  • Grant DL, Mes J, Frank R (1975) PCB residues in human tissue and milk. Proceedings of the National Conference on Polychlorinated Biphenyl, Chicago, IL, November 19–21, pp 144–146.

    Google Scholar 

  • Greer ES, Miller DJ, Bruscato FN, Holt RL (1980) Investigation of pesticide residues in human adipose tissue in the Northeast Louisiana area. J Agric Food Chem 28: 76–78.

    PubMed  CAS  Google Scholar 

  • Hashemy Tonkabony SE, Soleimani-Amiri MJ (1978) Chlorinated pesticide residues in the body fat of people in Iran. Environ Res 16 (1–3): 419–422.

    PubMed  CAS  Google Scholar 

  • Hattula ML, Ikkala J, Isomaki M, Maatta K, Arstila AU (1976) Chlorinated hydrocarbon residues (PCB and DDT) in human liver, adipose tissue, and brain in Finland. Acta Pharmacol Toxicol 39: 545–554.

    CAS  Google Scholar 

  • Hayes W (1975) Toxicology of pesticides. Williams and Wilkins Publishers, Baltimore, MD.

    Google Scholar 

  • Hayes W (1982) Pesticides studied in man. Williams and Wilkins Publishers, Baltimore, MD.

    Google Scholar 

  • Hoffman W (1967) Relation of pesticide concentration in fat to pathological changes in tissue. Arch Environ Hlth 15 (6): 758–765.

    CAS  Google Scholar 

  • Holdrinet MVH, Braun HE, Frank R, Stopps GJ, Smout MS, McWade JW (1977) Organochlorine residues in human adipose tissue, and milk from Ontario residents, 1969–74. Can J Pub Hlth 68: 74–80.

    CAS  Google Scholar 

  • Holt RL, Cruse S, Greer ES (1986) Pesticide and polychlorinated biphenyl residues in human adipose tissue from Northeast Louisiana. Bull Environ Contam Toxicol 36: 651–655.

    PubMed  CAS  Google Scholar 

  • Hruba D, Dubsky H, Totusek J, Polach J (1984) Residues of organochlorine pesticides found in human adipose tissues in the South Moravian Region. Scripta Medica 57 (7): 421–432.

    CAS  Google Scholar 

  • Jan J (1983) Chlorobenzene residues in human fat and milk. Bull Environ Contam Toxicol 30: 595–599.

    PubMed  CAS  Google Scholar 

  • Jensen A A (1987) Polychlorobiphenyls (PCBs), polychlorodibenzo-p-dioxins (PCDDs) and polychlorodibenzofurans (PCDFs) in human milk, blood, and adipose tissue. Sci Total Environ 64 (3): 259–293.

    PubMed  CAS  Google Scholar 

  • Jenson GE, Clausen J (1979) Organochlorine compounds in adipose tissue of Greenlanders and Southern Danes. J Toxicol Environ Hlth 5: 617–629.

    Google Scholar 

  • Juszkiewicz T, Stec J (1971) Polychlorinated insecticide residues in adipose tissue of farmers in the Lublin Province (Poland). Polski Tygodnik LeKarski 26: 462–464.

    PubMed  CAS  Google Scholar 

  • Juszkiewicz T, Niewiadowska A, Radomanski T (1977) Polychlorinated biphenyl residues in human adipose tissue. Polski Tygodnik Lekarski 32 (5): 173–175.

    PubMed  CAS  Google Scholar 

  • Juszkiewicz T, Sikorski R, Niewiadowska A, Radomanski T (1979) Traces of polychlorinated-diphenyls in the adipose tissue, and in the breast milk. Ginerologia Polska 50 (11): 917–922.

    CAS  Google Scholar 

  • Kaphalia BS, Seth TD (1983) Chlorinated pesticide residues in blood plasma, and adipose tissue of normal and exposed human population. Ind J Med Res 77: 245–247.

    CAS  Google Scholar 

  • Karakaya AE, Ozalp S (1987) Organochlorine pesticides in human adipose tissue collected in Ankara (Turkey) 1984–85. Bull Environ Contam Toxicol 38: 941–945.

    PubMed  CAS  Google Scholar 

  • Kraul I, Karlog O (1976) Persistent organochlorinated compounds in human organs collected in Denmark 1972–73. Acta Pharmacol Toxicol 38 (1): 38–48.

    CAS  Google Scholar 

  • Krewski D, Collin D, Villeneuve D (1986) Environmental health risk assessment: hexachlorobenzene. In: Morris CR, Cabrel JRP (eds) Hexachlorobenzene: Proceedings of an International Symposium, Lyon, France, 24–28 June, 1985. I ARC Publication No. 77. Oxford University Press, New York, pp 621–628.

    Google Scholar 

  • Kutz FW (1983) Chemical exposure monitoring. Residue Reviews 85: 277–292.

    PubMed  CAS  Google Scholar 

  • Kutz FW, Sovocool GW, Strassman S, Lewis RG (1976) trans-Nonachlor residues in human adipose tissue. Bull Environ Contam Toxicol 16:9–14.

    Google Scholar 

  • Kutz FW, Strassman SC, Sperling JF (1979) Survey of selected organochlorine pesticides in the general population of the United States: fiscal years 1970–75. Ann NY Acad Sci 320: 60–68.

    PubMed  CAS  Google Scholar 

  • Kutz FW, Strassman SC, Stroup CR, Carra JS, Leninger CC, Watts DL, Sparacino CM (1985) The human body burden of mirex in the Southeastern United States. J Toxicol Environ Hlth 15: 385–394.

    CAS  Google Scholar 

  • Kutz FW, Yobs AR, Johnson WB, Wiersma GB (1974a) Pesticide residues in adipose tissue of the general population of the United States, FY 1970 survey. Bull Soc Pharmacol Environ Toxicol 2: 4–10.

    CAS  Google Scholar 

  • Kutz FW, Yobs AR, Johnson WG, Wiersma GB (1974b) Mirex residues in human adipose tissue. Environ Entomol 3 (5): 882–884.

    CAS  Google Scholar 

  • Kutz FW, Yobs AR, Strassman SC (1976) Organochlorine pesticide residues in human adipose tissue. Bull Soc Pharmacol Environ Toxicol 3: 17–19.

    Google Scholar 

  • Kutz FW, Yobs AR, Strassman SC (1977a) Racial stratification of organochlorine insecticide residues in human adipose tissue. J Occup Med 19: 619–622.

    CAS  Google Scholar 

  • Kutz FW, Yobs AR, Strassman SC, Viar JF Jr (1977b) Effects of reducing DDT usage on total DDT storage in humans. Pestic Monit J 11: 61–63.

    CAS  Google Scholar 

  • Leininger C, Watts DL, Sparacino C, Williams S (1980) Mirex residue levels in human adipose tissue: A statistical evaluation. 560/13-80-024, U.S. Environmental Protection Agency, Office of Toxic Substances. Research Triangle Park, NC.

    Google Scholar 

  • Leoni V, D’Arca SU (1976) Experimental data and critical review of the occurrence of hexachlorobenzene in the Italian environment. Sci Total Environ 5: 253–272.

    CAS  Google Scholar 

  • Leoni V, DeLuca E, Biocca M (1978) Accumulation of data on the presence of organochlorine pesticides in human adipose tissue. Nuovi Ann Ig Microbiol 28 (1): 15–24.

    Google Scholar 

  • Lucas RM, Erickson MD, Piserchia PV, Williams SR (1980) PCB residue levels in human adipose tissue, a statistical evaluation by racial grouping. 560/13-79-015, U.S. Environmental Protection Agency, Office of Toxic Substances. Research Triangle Park, NC.

    Google Scholar 

  • Luckas B, Predel W, Vietinghoff U (1981) On the contamination of human fat from Rostock citizens with DDT and polychlorinated biphenyls in 1979. Die Nahrung 25 (5): 427 - 433.

    PubMed  CAS  Google Scholar 

  • Matsumura F (1975) Toxicology of insecticides. Plenum Press, New York.

    Google Scholar 

  • Matthews HB (1986) Factors determining hexachlorobenzene distribution, and persistence in higher animals. In: Morris CR, Cabrel JRP (eds) Hexachlorobenzene: Proceedings of an International Symposium, Lyon, France, 24–28 June, 1985. IARC Publication No. 77. Oxford University Press, New York. pp. 253–259.

    Google Scholar 

  • Menzie CM (1986) Hexachlorobenzene: Uses and occurrences. In: Morris CR, Cabrel JRP (eds) Hexachlorobenzene: Proceedings of an International Symposium, Lyon, France, 24–28 June, 1985. IARC Publication No. 77. Oxford University Press, New York, pp 13–22.

    Google Scholar 

  • Mes J, Campbell DS, Robinson RN, Davies DJA (1977) Polychlorinated biphenyl and organochlorine pesticide residues in adipose tissue of Canadians. Bull Environ Contam Toxicol 17 (2): 196–203.

    PubMed  CAS  Google Scholar 

  • Mes J, Davies DJ, Turton D (1982) Polychroinated biphenyl and other chlorinated hydrocarbon residues in adipose tissue of Canadians. Bull Environ Contam Toxicol 28: 97–104.

    PubMed  CAS  Google Scholar 

  • Mes J, Davies D, Turton D (1985) Environmental contaminants in human fat: A comparison between accidental and nonaccidental causes of death. Ecotoxicol Environ Saf 10: 74–75.

    Google Scholar 

  • Metcalf R (1981) Insect control technology. In: Kirk-Othmer encyclopedia of chemical technology, Vol 13, 3rd Edn, Wiley-Interscience Publication, New York.

    Google Scholar 

  • Morgan DP, Roan CC (1970) Hydrocarbon pesticide residues in human tissues. Arch Environ Hlth 20: 452–457.

    CAS  Google Scholar 

  • Mori Y, Kikuta M, Okinaga E, Okura T (1983) Levels of PCBs and organochlorine pesticides in human adipose tissue collected in Ehime Prefecture. Bull Environ Contam Toxicol 30: 74–79.

    PubMed  CAS  Google Scholar 

  • Morita M, Mimura S, Ohi G, Yagyu H (1975) A systematic determination of chlorinated benzenes in human adipose tissue. Environ Pollut 9 (3): 175–179.

    CAS  Google Scholar 

  • Morita M, Ohi G (1975) p-dichlorobenzene in human tissue and atmosphere in Tokyo metropolitan area. Environ Pollut 8:269–274.

    Google Scholar 

  • Mughal HA, Rahman MA (1973) Organochlorine pesticide content of human adipose tissue in Karachi. Arch Environ Hlth 27 (6): 396–398.

    CAS  Google Scholar 

  • Mukherjee D, Ghosh BN, Chakraborty J, Roy BR (1980) Pesticide residues in human tissues in Calcutta. Ind J Med Res 72: 583–587.

    CAS  Google Scholar 

  • Murphy S (1986) Toxic effects of pesticides. In: Klassen C, Amdur M, Doull J (eds) Casarett and Doull’s toxicology, the basic science of poisons. MacMillan Publishing Company, New York, pp 519–581.

    Google Scholar 

  • Mussalo-Rauhamaa H, Pyysalo H, Moilanen R (1984) Influence of diet and other factors on the levels of organochlorine compounds in the human adipose tissue. J Toxicol Environ Hlth 13: 689–704.

    CAS  Google Scholar 

  • Niessen KH, Ramolla J, Binder M, Brugmann G, Hofmann U (1984) Chlorinated hydrocarbons in adipose tissue of infants and toddlers: inventory and studies on their association with intake of mother’s milk. Eur J Ped 142 (4): 238–243.

    CAS  Google Scholar 

  • Nishimoto T, Ueda M, Taue S, Chikazaw H, Nishiyama T (1973) PCT (poly chlorotriphenyl) in human adipose tissue and mothers milk. Igaku No Ayumi 87 (5): 264–265.

    CAS  Google Scholar 

  • O’Brien RD (1967) Insecticide action and metabolism. Academic Press, New York.

    Google Scholar 

  • Okond’ Ahoka O (1984) Study on human contamination by organohalogen pesticides in Zaire. Ann Falsif Expert Chin Toxicol 77 (832): 531–40.

    Google Scholar 

  • Penumarthy L, Oehme FW, Spaulding JE, Rader WA (1976) Toxaphene: livestock toxicity and tissue residues. Vet Toxicol 18: 60.

    CAS  Google Scholar 

  • Pollock G, Kilgore W (1978) Toxaphene. Residue Reviews 69: 87–140.

    CAS  Google Scholar 

  • Polpyk M (1989) Farm chemicals handbook. Meister Publishing Company, Willough- by, OH.

    Google Scholar 

  • Pozo Lora R, Herrea Marteache A, Pole Villar L, Jodral Villarejo M, Mallol Escobar J, Polo Villar G (1978) Presence of the synthetic fungicide, hexachlorobenze, in human fatty tissues in Spain. Part I. Rev Sanid Hig Pub (Madrid) 52:1145–1150 (cited in Hayes 1982 ).

    Google Scholar 

  • Prati L, Del Dot M (1971) Accumulation levels of synthetic organochlorine pesticides in human adipose tissue in the province of Trent Ig Mod 64: 1–6.

    Google Scholar 

  • Prati L, Pavanello R, Ghezzo F (1972) Storage of chlorinated pesticides in human organs and tissues in Ferrara Province, Italy. Bull World Hlth Org 46: 363–369.

    CAS  Google Scholar 

  • Pyysalo H (1984) Trend in the contents of neutral organochlorine compounds in Finnish nature and concentration in Finnish human adipose tissue. Kemi-Kemi 11 (1): 22–25.

    CAS  Google Scholar 

  • Ramachandran M, Banerjee BD, Gulati M, Grover A, Zaidi SSA, Hussain QC (1984) DDT and HCH residues in the body fat and blood samples from some Delhi hospitals. Ind J Med Res 80: 590–593

    CAS  Google Scholar 

  • Rappolt RT, Hale WE (1968) p,p’-DDT residues in human placentas, cords, and adipose tissue. Clin Toxicol 1(1):57–61.

    Google Scholar 

  • Redetzke KA, Gonzalez AA, Applegate HG (1983) Organochlorine pesticides in adipose tissue of persons from Ciudad Juarez, Mexico. J Environ Hlth 46: 25–27.

    CAS  Google Scholar 

  • Ritcey WR, Savary G, McCully KA (1973) Organochlorine insecticide residues in human adipose tissue of Canadians. Can J Pub Hlth 64 (4): 380–386.

    CAS  Google Scholar 

  • Robinson J (1971) Organochlorine compounds in man and his environment. Chem Brit 7: 472–475.

    CAS  Google Scholar 

  • Robinson PE, Leczynski BA, Kutz FW, Remmers JC (1986) An evaluation of hexachlorobenzene body burden levels in the general population of the USA. In: Morris CR, Cabral JRP (eds) Hexachlorobenzene: Proceedings of an International Symposium, Lyon, France, 24–28 June 1985. IARC Publication No. 77. Oxford University Press, New York.

    Google Scholar 

  • Schnare DW, Ben M, Shields MG (1984) Body burden reductions of PCBs, PBBs and chlorinated pesticides in human subjects. Ambio 13 (5–6): 378–380.

    Google Scholar 

  • Schulte E (1975) Contamination of humans with chlorinated hydrocarbons, particularly PCB2. Comm Eur Communities (Rep.) EUR 5196 Probl Raised Contam Man Environ Persistent Pestic. Organo-halogenated Cmpds. pp 435–440.

    Google Scholar 

  • Siddiqui MKJ, Saxena MC, Krishna CR (1981) Storage of DDT and BHC in adipose tissue of Indian males. Ind J Environ Anal Chem 10: 197–204.

    CAS  Google Scholar 

  • Solly ARB, Shanks V (1974) Polychlorinated biphenyls and organochlorine pesticides in human fat in New Zealand. New Zealand J Sci 17: 535–544.

    CAS  Google Scholar 

  • SRC (Syracuse Research Corporation) (1987) Toxicological profiles for selected PCBs. Agency for Toxic Substance and Disease Registry (ATSDR), U.S. Public Health Service, Washington, DC.

    Google Scholar 

  • Sugiyama S, Noda H, Yamaguchi M, Yamada T, Mitsukuni Y, Doi S, Yoshimura M (1981) Studies on organochlorinated pesticides in human organs and tissues (V). Med J Kinki Univ 6 (2): 183–191.

    CAS  Google Scholar 

  • Syrowatka T, Palut D, Gorski T (1978) The content of polychlorinated biphenyls in the adipose tissue of the population of Warsaw and its environment. Roczniki Panstwowego Zakladu Higieng 29 (4): 439–443.

    CAS  Google Scholar 

  • Syrowatka T, Palut D, Gorski T, Tulczynski A (1979) Residues of chloroorganic pesticides in adipose tissue of the population of Warsaw and its environment. Roczniki Panstwowego Zakladu Higieng 30 (5): 505–509.

    CAS  Google Scholar 

  • Szymczynski GA, Waliszewski SM (1981) Comparison of the content of chlorinated pesticide residues in human semen, testicles, and fat tissues. Andrologia 13: 250–252.

    PubMed  CAS  Google Scholar 

  • Szymczynski GA, Waliszewski SM, Tuszowski M, Pyda P (1986) Chlorinated pesticide levels in human adipose tissue in the District of Poznan. J Environ Sci Hlth A21 (1): 5–14.

    Google Scholar 

  • Tanabe S, Kannan N, Subramanian AN, Watanabe S, Tatsukawa R (1987) Highly toxic coplanar PCBs: Occurrence, source, persistence, and toxic implications to wildlife and humans. Environ Pollut 47: 147–163.

    PubMed  CAS  Google Scholar 

  • To-Figueras J, Rodamilans M, Gomez J, Corbella J (1986) Hexachlorobenzene residues in the general population of Barcelona (Spain). In: Morris CR, Cabral JRP (eds) Hexachlorobenzene: Proceedings of an International Symposium, Lyon, France, 24–28 June 1985. IARC Publication No. 77. Oxford University Press, New York, pp 147–182.

    Google Scholar 

  • de Vlieger M, Robinson J, Baldwin MK, Crabtree AN, Dijk MC (1968) The organochlorine insecticide content of human tissues. Arch Environ Hlth 17: 759–767.

    Google Scholar 

  • U.S. Environmental Protection Agency (1979) Ambient water quality criteria for hexachlorocyclohexane. EPA-440/5-80-054: Office of Water Regulations and Standards, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1980a) Ambient water quality criteria for DDT. EPA-440/5-08-038: Office of Water Regulations and Standards, Criteria and Standards Division, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1980b) Ambient water quality criteria for toxaphene. EPA-4-10/5-80-076: Office of Water Regulations and Standards, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1980c) Ambient water quality criteria for endrin. EPA-440-5-80-047: Office of Water Regulations and Standards, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1985a) Suspended, cancelled and restricted pesticides, third revision. Office of Pesticides and Toxic Substances, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1985b) Baseline estimates and time trends for beta-benzene hexachloride, hexachlorobenzene, and polychlorinated biphenyls in human adipose tissue 1970–83. EPA-560/5-85-025: Office of Toxic Substances, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1986) Geometric means for selected organochlorine compounds in adipose tissue (unpublished). Office of Toxic Substances, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency, (1986a) Broad scan analysis of the FY82 National Human Adipose Tissue Survey specimens. Vol III—Semi-Volatile Organic Compounds. EPA-560/5-85-625: Office of Toxic Substances, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1986b) Exposure assessment for hexachlorobenzene. EPA-560/5-86-019: Office of Toxic Substances, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1986c) Broad scan analysis of the FY82 National Human Adipose Tissue Survey specimens. Vol I—Executive Summary. EPA-560/5-86-035: Office of Toxic Substances, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1987a) Chlordane, heptachlor, aldrin, and dieldrin. Technical Support Document (draft). Office of Pesticide Programs, Washington, DC.

    Google Scholar 

  • U.S. Environmental Protection Agency (1987b) Health Advisory for Dieldrin (draft). Office of Drinking Water, Washington, DC.

    Google Scholar 

  • U.S. Food and Drug Administration (1981) FDA surveillance index for pesticides. U.S. Food and Drug Administration, Washington, DC.

    Google Scholar 

  • Van Haver W, Vandezande A, Gordts L (1978) Organochlorine pesticides in human fatty tissue. Arch Beg Med Soc Hyg Med Trav Med Leg 36 (3): 147–155.

    Google Scholar 

  • Warnick SL (1972) Organochlorine pesticide levels in human serum and adipose tissue Utah—fiscal years 1969–71. Pestic Monit J 6: 9–13.

    PubMed  CAS  Google Scholar 

  • Warnick SL, Eldredge JD (1972) Human and environmental exposure to pesticides in Utah. Proc Utah Acad Sci Arts Lett 49: 11–20.

    CAS  Google Scholar 

  • Wassermann M, Tomatis L, Wassermann D, Day NE, Groner Y, Lazarovici S, Rosenfeld D (1974) Epidemiology of organochlorine insecticides in the adipose tissue of Israelis. Pestic Monit J 8 (1): 1–7.

    PubMed  CAS  Google Scholar 

  • World Health Organization (1974) IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Some organochlorine pesticides, Vol 5. WHO, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (1978) IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Polychlorinated biphenyls and polybrominated biphenyls, Vol 18. WHO, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (1979a) IARC monographs on the evaluation of carcinogenic risk of humans. Some halogenated hydrocarbons, Vol 20. WHO, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (1979b) Environmental Health Criteria, No. 9. DDT and its derivations. WHO, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (1988a) Health and safety guide for heptachlor. WHO, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (1988b) Health and Safety guide for chlordane. WHO, Geneva, Switzerland.

    Google Scholar 

  • World Health Organization (1989) Aldrin and dieldrin health, and safety guide. WHO, Geneva, Switzerland.

    Google Scholar 

  • Williams DT, LeBel GL, Junkins E (1984) A comparison of organochlorine residues in human adipose tissue autopsy samples from two Ontario municipalities. J Toxicol Environ Hlth 13: 19–29.

    CAS  Google Scholar 

  • Wisswesser WJ (ed) (1976) Pesticide index, 5th ed. Entomological Soc of America, College Park, MD.

    Google Scholar 

  • Wit SL (1971) Persistente insecticiden in Netherlands lichaamsvet. Chemish Weekblad. 29 Januari 1971.

    Google Scholar 

  • Wolff MS, Anderson HA, Selikoff IJ (1982) Human tissue burdens of halogenated aromatic chemicals in Michigan. J Am Med Assoc 247 (15): 2112–2116.

    CAS  Google Scholar 

  • Wyllie J, Gabica J, Benson W (1972) Comparative organochlorine pesticide residues in serum and biopsied lipoid tissue: A survey of 200 persons in southern Idaho 1970. Pestic Monit J 6 (2): 84–88.

    PubMed  CAS  Google Scholar 

  • Yamada T, Sugiyama S, Noda H, Mitsukuni Y, Yoshimura M (1976) Organo- chlorinated pesticides in human organs and tissues. Nippon Hoigaku Zusshi 30 (6): 416–426.

    CAS  Google Scholar 

  • Yobs AR (1972) Levels of polychlorinated biphenyls in adipose tissue of the general population of the Nat. Environ Hlth Perspect 1: 79–81.

    CAS  Google Scholar 

  • Yoshimura M (1985) Indices on accumulation of pollutants in human body from forensic autopsy materials. Nippon Hoigaku Zasshi 39 (6): 440–468.

    Google Scholar 

  • Yoshimura M, Yamada T, Sugiyama S (1986) Secular changes of organochlorinated pesticides accumulated in organ and tissue of Japanese: IV. Kankyo Kagaku Kenkyusho Kenkyu Hokoku 14: 161–165.

    CAS  Google Scholar 

  • Yosimura M, Yamada T, Sugiyama S, Noda H, Misukuni Y (1979) Organochlorinated pesticides in human organs and tissues. Jap J Legal Med, 33 (2): 91–102.

    Google Scholar 

  • Yoshimura M, Yamada T, Sugiyama S, Noda H, Mitsukuni Y, et al(1981) Studies on organochlorinated pesticides in human organs and tissues: IV. Nippon Hoigaku Zusshi 33 (2): 91–102.

    Google Scholar 

  • Zarkovic G, Custovic-Begovic F, Adamovic V, Bauer K, Jan J (1973) Contamination of foodstuffs and human fatty tissue by pesticide residues in Yugoslavia in 1969–71. Arh Hig Rada Toksikol 13 (4): 381–394.

    Google Scholar 

  • Zitko V (1979) PCB levels in human adipose tissue and population density. Chemosphere 2: 45–46.

    Google Scholar 

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Authors and Affiliations

  1. Office of Modeling, Monitoring Systems and Quality Assurance, Office of Research and Development, U.S. Environmental Protection Agency, 401 M Street S.W., Washington, DC, 20460, USA

    Frederick W. Kutz

  2. Versar Inc., Environmental Operations, 6850 Versar Center, Springfield, VA, 22151, USA

    Patricia H. Wood & David P. Bottimore

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  1. Frederick W. Kutz
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  2. Patricia H. Wood
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  3. David P. Bottimore
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Editors and Affiliations

  1. College of Agriculture, University of Arizona, Tucson, Arizona, 85721, USA

    George W. Ware

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Kutz, F.W., Wood, P.H., Bottimore, D.P. (1991). Organochlorine Pesticides and Polychlorinated Biphenyls in Human Adipose Tissue*. In: Ware, G.W. (eds) Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, vol 120. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3080-9_1

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  • DOI: https://doi.org/10.1007/978-1-4612-3080-9_1

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