Abstract
Pyrrolizidine alkaloids are of common occurrence in plants, particularly in genera such as Senecio, Crotalaria, Symphytum, Echium and Heliotropium (1). Retronecine (1) and heliotridine (2), and numerous simple and complex esters of these and related alkaloids, are typical pyrrolizidines. Many pyrrolizidine alkaloids are potent hepatotoxins and carcinogens (2); thus, the pyrrolizidines have been widely studied and are considered to be among the most important groups of natural products in terms of their effects on human health and economic activities (3).
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Powell, R.G., Petroski, R.J. (1992). The Loline Group of Pyrrolizidine Alkaloids. In: Pelletier, S.W. (eds) Alkaloids: Chemical and Biological Perspectives. Alkaloids: Chemical and Biological Perspectives, vol 8. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2908-7_4
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DOI: https://doi.org/10.1007/978-1-4612-2908-7_4
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