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The Role of the Cerebellum in Voluntary and Reflexive Movements: History and Current Status

  • Chapter
The Cerebellum Revisited

Abstract

Because important scientific questions are usually examined by a number of research groups that may differ from each other in both methodology and theoretical orientation, it is not unusual to have opposing interpretations of a research outcome. Moreover, the interpretation of any single research group may be powerfully influenced and rewarded by the culture, politics, and historical precedents to which it has been exposed. Therefore, the validity of a scientific interpretation and its recognition as “truth” by the scientific community is greatly enhanced when that truth is arrived at by independent research groups differing in their intellectual backgrounds and coming from altogether different historical frameworks. Such has been the case with the study of cerebellar function. Thus, one purpose of this chapter is to review how similar conceptions of cerebellar function were arrived at by two different and to a large extent noninteractive groups of scientists: the first located in the “West,” by which is meant western Europe and the western hemisphere, and the second in the USSR.

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References

  • Albus, J.S. (1971): A theory of cerebellar function. Math. Biosci, 10, 25–61.

    Article  Google Scholar 

  • Beck, E.C., and Doty, R.W. (1957): Conditioned flexion reflexes acquired during combined catalepsy and de-efferentiation. J. Comp. Physiol. Psychol, 50, 211–216.

    Article  PubMed  CAS  Google Scholar 

  • Berthier, N.E., and Moore, J.W. (1983): The nictitating membrane response: An electrophysiological study of the abducens nerve and nucleus and the accessory abducens nucleus in rabbit. Brain Res., 258,201–210.

    Article  PubMed  CAS  Google Scholar 

  • Brooks, V.B. (1986): The Neural Basis of Motor Control New York: Oxford University Press.

    Google Scholar 

  • Bykov, K.M. (1957): The Cerebral Cortex and the Internal Organs (W.H. Gantt, ed.). New York: Chemical Rubber Co.

    Google Scholar 

  • Crisler, G. (1930): Salivation is unnecessary for the establishment of the salivary conditioned reflex induced by morphine. Am. J. Physiol, 94, 553–556.

    Google Scholar 

  • Dickenson, W.H. (1865): On the functions of the cerebellum. Br. For. Medico-Chirurgical Rev., 26, 455–480.

    Google Scholar 

  • Evarts, E.V. (1966): Pyramidal tract activity associated with a conditioned hand movement in the monkey. J. Neurophysiol, 29, 1011–1027.

    PubMed  CAS  Google Scholar 

  • Fanardjian, V.V. (1961): The influence of cerebellar ablation on conditioned motor reflexes in dogs (G.G. Champe, Transl, J.P. Welsh, and J.A. Harvey, eds). Zhurnal Vyshei Nervoi D#x2019;eyatel#x2019;nost#x2019;, 11, 920–926.

    Google Scholar 

  • Finch, G. (1938): Salivary conditioning in atropinized dogs. Am. J. Physiol., 124, 136–141.

    CAS  Google Scholar 

  • Gambaryan, L.S. (1960): Conditioned avoidance reflexes induced in dogs with cerebellar lesions. Physiologia Bohemoslovenica, 9, 261–266.

    Google Scholar 

  • Gantt, W.H. (1989): Notes on Pavlov written while I was in Russia (1922–1927). Pavlovian J. Biol. Sci., 1, 1–5.

    Google Scholar 

  • Gormezano, I., Kehoe, E.J, and Marshall, B.S. (1983): Twenty years of classical conditioning with the rabbit. In: Progress in Psychobiology and Physiological Psychology, Vol. 10(J.M. Sprague, and A.N. Epstein, eds). New York: Academic Press, pp. 197–275.

    Google Scholar 

  • Gray, T.S, McMaster, S.E, Harvey, J.A, and Gormezano, I. (1981): Localization of retractor bulbi motoneurons in the rabbit. Brain Res., 226, 93–106.

    Article  PubMed  CAS  Google Scholar 

  • Harvey, J.A. (1987): Effects of drugs on associative learning. In: Psychopharmacology, the Third Generation of Progress (H. Meltzer, ed.). New York: Raven Press, pp. 1485–1491.

    Google Scholar 

  • Harvey, J.A, Gormezano, I, and Cool-Hauser, V.A. (1985): Relationship between heterosynaptic reflex facilitation and acquisition of the nictitating membrane response in control and scopolamine injected rabbits. J. Neurosci., 5, 596–602.

    PubMed  CAS  Google Scholar 

  • Harvey, J.A, Land, T, and McMaster, S.E. (1984): Anatomical study of the rabbit’s corneal-VIth nerve reflex: Connections between cornea, trigeminal sensory complex, and the abducens and accessory abducens nuclei. Brain Res., 301, 307–321.

    Article  PubMed  CAS  Google Scholar 

  • Heindel, W.C, Salmon, D.P., Shults, C.W, Walicke, P.A, and Butters, N. (1989): Neuropsychological evidence for multiple implicit memory systems: A comparison of Alzheimer’s, Huntington’s, and Parkinson’s disease patients. J. Neurosci., 9, 582–587.

    PubMed  CAS  Google Scholar 

  • Holmes, G. (1917): The symptoms of acute cerebellar injuries due to gunshot injuries. Brain, 40,461–535.

    Article  Google Scholar 

  • Holmes, G (1939): The cerebellum of man. Brain, 62, 1–30.

    Article  Google Scholar 

  • Holstege, G, Tan, J, van Ham, J.J, and Graveland, G.A. (1986): Anatomical observations on the afferent projections to the retractor bubli motoneuronal cell group and other pathways possibly related to the blink reflex in cat. Brain Res., 374, 321–334.

    Article  PubMed  CAS  Google Scholar 

  • Houk, J.C., Singh, S.P., Fisher, C., and Barto, A.G (1990): An adaptive sensorimotor network inspired by the anatomy and physiology of the cerebellum. In: Neural Networks for Control (W.T. Miller, R.S. Sutton, and P.J. Werbos, eds). Cambridge: MIT Press, pp. 301–348.

    Google Scholar 

  • Ito, M. (1984): The Cerebellum and Neural Control. New York: Raven Press.

    Google Scholar 

  • Karamyan, A.I. (1959): The evolution of corticocerebellar functional relationships (G.G Champe, Transl, J.P. Welsh, and J.A. Harvey, eds). Zhurnal Vyshei Nervoi D’eyatel’nost’, 3, 346–444.

    Google Scholar 

  • Karamyan, A.I. (1962): Evolution of the Function of the Cerebellum and Cerebral Hemispheres (M. Roublev, Transl.). Washington D.C.: National Science Foundation.

    Google Scholar 

  • Karamyan, A.I. (1968): On the evolution of the integrative activity of the central nervous system in the phylogeny of vertebrates. In: Progress in Brain Research, Vol. 22, Brain Reflexes (E.A. Asratyan, ed.). Amsterdam: Elsevier, pp. 427–447.

    Google Scholar 

  • Karamyan, A.I, Fanardjian, V.V, and Losareva, A.A. (1969): The functional and morphological evolution of the cerebellum and its role in behavior. In: Neurobiology of Cerebellar Evolution and Development (R. Llinás, ed.). Chicago: American Medical Association Education and Research Foundation, pp. 639–673.

    Google Scholar 

  • Kellogg, W.N, Scott, V.B, Davis, R.C, and Wolf, I.S. (1940): Is movement necessary for learning? J. Comp. Psychol., 29, 43–74.

    Article  Google Scholar 

  • Krasusky, V.K. (1957): General nature of changes of food conditioned reflexes in dogs following a surgical lesion of the cerebellum (G.G Champe, Transl, J.P. Welsh and J.A. Harvey, eds). Zhurnal Vyshei Nervoi D’eyatel’nosti; ,5,733–740.

    Google Scholar 

  • Lashley, K.S, and McCarthy, DA. (1926): The survival of the maze habit after cerebellar injuries. J. Comp. Physiol. Psychol., 6, 423–433.

    Google Scholar 

  • Light, J.S, and Gantt, W.H. (1936): Essential part of reflex arc for establishment of conditioned reflex. Formation of conditioned reflex after exclusion of motor peripheral end. J. Comp. Psychol., 21,19–36.

    Google Scholar 

  • Lisberger, S.G (1988): The neural basis for learning of simple motor skills. Science, 242, 728–735.

    Article  PubMed  CAS  Google Scholar 

  • Livshits, N.N. (1947): Effect of cerebellar extirpation on the conditioned reflexes of dogs. In: Trudy Fisiologicheskogo Instituta im. Pavlova, Vol. II (G.G Champe, Transl, J.P. Welsh, and J.A. Harvey, eds). Moscow: USSR Academy of Sciences, pp. 11–50.

    Google Scholar 

  • Llinás, R, and Walton, K. (1979): Place of the cerebellum in motor learning. In: Brain Mechanisms in Memory and Learning: From the Single Neuron to Man (M.A.B. Brazier, ed.). New York: Raven Press, pp. 17–36.

    Google Scholar 

  • Lopiano, L., de’Sperati, C., Bergui, M, and Montarolo, P.G (1989): Role of the cerebellar vermis in the long-term habituation of the acoustic startle response in the rat. In: The Olivocerebellar System in Motor Control, Exper. Brain Res. Series 17 (P. Strata, ed.). Berlin-Heidelberg: Springer-Verlag, pp. 380–384.

    Google Scholar 

  • Luciani, L. (1915): The hind-brain. In: Human Physiology (F. Welby, Transl, G.M. Holmes, ed.). London: MacMillan and Co., pp. 419–486.

    Google Scholar 

  • Marek, G.J., McMaster, S.E., Gormezano, I., and Harvey, J A. (1984): The role of the accessory abducens nucleus in the rabbit nictitating membrane response. Brain Res., 299, 215–229.

    Article  PubMed  CAS  Google Scholar 

  • Marr, D. (1969): A theory of cerebellar cortex. J. Physiol. (Lond.), 202, 437–470.

    CAS  Google Scholar 

  • McCormick, D.A., Lavond, D.G., Clark, G.A., Kettner, R.E., Rising, CE, and Thompson, R.F. (1981): The engram found? Role of the cerebellum in classical conditioning of the nictitating membrane and eyelid responses. Bull. Psychonomic Soc, 18, 103–105.

    Google Scholar 

  • McCormick, DA., and Thompson, R.F. (1984): Cerebellum: Essential involvement in the classically conditioned eyelid response. Science, 233, 296–299.

    Article  Google Scholar 

  • Meyer-Lohmann, J., Hore, J., Brooks, V.B. (1977): Cerebellar participation in generation of prompt arm movements. J. Neurophysiol, 40, 1038–1050.

    PubMed  CAS  Google Scholar 

  • Moore, J.W., and Blazis, D.E.J. (1989): Cerebellar implementation of a computational model of classical conditioning. In: The Olivocerebellar System in Motor Control, Exper. Brain Res. Series 17 (P. Strata, ed.). Berlin-Heidelberg: Springer-Verlag, pp. 387–399.

    Google Scholar 

  • Orbeli, LA. (1940): New concepts concerning cerebellar function (G.G. Champe, Transl, J.P. Welsh and J.A. Harvey, eds). Usp’ekhi Sovrem’ennoy Biologii, 13, 207–220.

    Google Scholar 

  • Pavlov, LP. (1927): Conditioned Reflexes (G.V. Anrep, Transl.). New York: Dover

    Google Scholar 

  • Polenchar, B.E., Patterson, M.M., Lavond, D.G., and Thompson, R.F. (1985): Cerebellar lesions abolish an avoidance response in the rabbit. Behav. Neural Biol, 44, 221–227.

    Article  PubMed  CAS  Google Scholar 

  • Pollock, L.J., and Davis, L. (1927): Influence of the cerebellum upon the reflex activities of the decerebrate animal. Brain, 50, 277–312.

    Article  Google Scholar 

  • Popov, N.F. (1929a): Notes for the study of cerebellar function. In: Vishaya N’ervnaya D’eyatel’nost’: Sbornik Trudov Instituta, Vol. 1 (D.S. Fursikov, M.O. Gurevich, A.N. Zalmanzon, eds). (G.G. Champe, Trans., J.P. Welsh and J.A. Harvey, eds). Moscow: Komunisticheskaya Akademiya Institutvishey Nervnoy D’eyatel’nost’, pp. 93–139.

    Google Scholar 

  • Popov, N.F. (1929b): The role of the cerebellum in the formation of conditioned motor reflexes. In: Vishaya N’ervnaya D’eyatel’nost’: Sbornik Trudov Instituta, Vol. 1, (D.S. Fursikov, M.O. Gurevich, A.N. Zalmanzon, eds) (G.G. Champe, Transl., J.P. Welsh, and J.A. Harvey, eds). Moscow: Komunisticheskaya Akademiya Institutvishey Nervnoy D’eyatel’nost’, pp. 140–148.

    Google Scholar 

  • Prince, J.H. (1964): The Rabbit in Eye Research. Springfield, IL: Charles C. Thomas.

    Google Scholar 

  • Rawson, N.R. (1932): The story of the cerebellum. Can. Med. Assoc. J., 26, 220–225.

    PubMed  CAS  Google Scholar 

  • Sakurai, M. (1989): Depression and potentiation of parallel fiber-purkinje cell transmission in in vitro cerebellar slices. In: The Olivocerebellar System in Motor Control, Exper. Brain Res. Series 17 (P. Strata, ed.). Berlin-Heidelberg: Springer-Verlag, pp. 221–230.

    Google Scholar 

  • Sechenov, I. (1863): Reflexes of the Brain. In: Selected Works, (A.A. Subhov, Transl. and ed.), Moscow-Leningrad: State House for Biological and Medical Literature (1935), pp. 263–336.

    Google Scholar 

  • Sherrington, C. (1906): The Integrative Action of the Nervous System. New Haven: Yale University Press.

    Google Scholar 

  • Skelton, R.W., Mauk, M.D., and Thompson, R.F. (1988): Cerebellar nucleus lesions dissociate alpha conditioning from alpha responses in rabbits. Psychobiology, 16, 126–134.

    Google Scholar 

  • Squire, L.R. (1987): Memory: Neural organization and behavior. In: Handbook of Physiology—The Nervous System V(F. Plum, ed.). Bethesda, MD: Am. Physiol Soc, pp. 295–371.

    Google Scholar 

  • Thompson, R.F. (1986): The neurobiology of learning and memory. Science, 233, 941–947.

    Article  PubMed  CAS  Google Scholar 

  • Walshe, F.M.R. (1927): The significance of the voluntary element in the genesis of cerebellar ataxy. Brain, 50, 377–390.

    Article  Google Scholar 

  • Weiser, M., Pastor, A.M., and Baker, R. (1989): Monocular adaptive gain control of the vestibulo-ocular reflex in the goldfish, Carassius auratus. Soc Neurosci. Abstr., 15, 807.

    Google Scholar 

  • Welsh, J.P. (1992): Changes in the motor pattern of learned and unlearned responses following cerebellar lesions: A kinematic analysis of the nictitating membrane reflex. Neurosci. 47, 1–19.

    Article  CAS  Google Scholar 

  • Welsh, J.P., and Harvey, J.A. (1989a): Cerebellar lesions and the nictitating membrane reflex: Performance deficits of the conditioned and unconditioned response. J. Neurosci., 9, 299–311.

    PubMed  CAS  Google Scholar 

  • Welsh, J.P., and Harvey, J.A. (1989b): Modulation of conditioned and unconditioned reflexes. In: The Olivocerebellar System in Motor Control, Exper. Brain Res. Series 17 (P. Strata, ed.). Berlin-Heidelberg: Springer-Verlag, pp. 374–379.

    Google Scholar 

  • Welsh, J.P., and Harvey, J.A. (1991): Pavlovian conditioning in the rabbit during inactivation of the interpositus nucleus. J. Physiol. (Lond.), 444, 459–480.

    CAS  Google Scholar 

  • Yeo, C.H., Hardiman, M.J., and Glickstein, M. (1985): Classical conditioning of the nictitating membrane responses of the rabbit. I. Lesions of the cerebellar nuclei. Exp. Brain Res., 60, 87–98.

    CAS  Google Scholar 

  • Yerkes, R.M., and Morgulis, S. (1909): The method of Pavlov in animal psychology. Psychol Bull, 6, 257–273.

    Article  Google Scholar 

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Authors
  1. John P. Welsh
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  2. John A. Harvey
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Editors and Affiliations

  1. Department of Physiology/Biophysics, New York University Medical Center, 550 First Avenue, 10016, New York, NY, USA

    Rodolfo Llinás

  2. INSERM U-106, Hôpital de la Salpêtrière, 47 Boulevard de l’Hôpital, 75013, Paris, France

    Constantino Sotelo M.D., Ph.D.

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Welsh, J.P., Harvey, J.A. (1992). The Role of the Cerebellum in Voluntary and Reflexive Movements: History and Current Status. In: Llinás, R., Sotelo, C. (eds) The Cerebellum Revisited. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2840-0_16

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  • DOI: https://doi.org/10.1007/978-1-4612-2840-0_16

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7691-3

  • Online ISBN: 978-1-4612-2840-0

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