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Human Malaria Transmission: Reconciling Field and Laboratory Data

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Advances in Disease Vector Research

Part of the book series: Advances in Disease Vector Research ((VECTOR,volume 10))

Abstract

The human malaria parasite life cycle appears deceptively simple because it involves only one species of vertebrate host (humans) and anopheline mosquitoes to transmit the pathogen. However, a number of host, vector, and pathogen factors have evolved that interact with ecological and logistic considerations to determine whether transmission of the parasite from a mosquito to a human, or the converse, will successfully occur.

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References

  1. Adungo, N.I., Mahadevan, S., Mulaya, N.L., Situbi, A.P., and Githure, J.I. 1991. Comparative determination of Plasmodium falciparum sporozoite rates in Afrotropical Anopheles from Kenya by dissection and ELISA. Ann. Trop. Med. Parasitol. 85:387–394.

    PubMed  CAS  Google Scholar 

  2. Allison, A.C. 1988. The role of cell-mediated immune responses in protection against plasmodia and in the pathogenesis of malaria. In W.H. Wernsdorfer and I. McGregor, eds., Malaria. Principles and Practices in Malariology, Vol. 1. Churchill Livingstone, Edinburgh, pp. 253–306.

    Google Scholar 

  3. Baird, J.K., Jones, T.R., Masbar, P.S., Ratiwayanto, S., and Leksana, B. 1991. Evidence for specific suppression of gametocytemia by Plasmodium falciparum in residents of hyperendemic Irian Jaya. Am. J. Trop. Med. Hyg. 44:183–190.

    PubMed  CAS  Google Scholar 

  4. Barker, R.H. 1990. DNA probe diagnosis of parasitic infections. Exp. Parasitol. 70:494–499.

    PubMed  Google Scholar 

  5. Beier, J.C., Onyango, F.K., Koros, J.K., Ramadan, M., Ogwang, R., Wirtz, R.A., Koech, D.K., and Roberts, C.R. 1991. Quantitation of malaria sporozoites transmitted by wild Afrotropical Anopheles. Med. Vet. Entomol. 5:71–79.

    PubMed  CAS  Google Scholar 

  6. Beier, J.C., Oster, C.N., Koros, J.K., Onyango, F.K., Githeko, A.K., Rowton, E., Koech, D.K., and Roberts, C.R. 1989. Effect of human circumsporozoite antibodies in Plasmodium-infected Anopheles (Diptera: Culicidae). J. Med. Entomol. 26:547–553.

    PubMed  CAS  Google Scholar 

  7. Boreham, P.F.L., Chandler, J.A., and Jolly, J. 1978. The incidence of mosquitoes feeding on mothers and babies at Kisumu, Kenya. J. Trop. Med. Hyg. 81:63–67.

    PubMed  CAS  Google Scholar 

  8. Boreham, P.F.L., and Garrett-Jones, C. 1973. Prevalence of mixed blood meals and double feeding in a malaria vector (Anopheles sacharovi Favre). Bull W.H.O. 48:605–614.

    PubMed  CAS  Google Scholar 

  9. Boreham, P.F.L., and Lenahan, J.K. 1976. Methods for detecting multiple blood meals in mosquitoes (Diptera: Culicidae). Bull. Entomol. Res. 66:671–679.

    Google Scholar 

  10. Boudin, C., Lyannaz, J., Bosseno, M.F., Carnevale, P., and Ambroise-Thomas, P. 1991. Epidemiology of Plasmodium falciparum in a rice field and a savanna area in Burkina Faso: seasonal fluctuations of gametocytaemia and malaria infectivity. Ann. Trop. Med. Parasitol. 85:377–385.

    PubMed  CAS  Google Scholar 

  11. Boyd, M.F. 1940. The influence of sporozoite dosage in vivax malaria. Am. J. Trop. Med. 20:279–286.

    Google Scholar 

  12. Boyd, M.F., and Stratman-Thomas, W.K. 1934. Studies on benign tertian malaria. 7. Some observations on inoculation and onset. Am. J. Hyg. 20:488–495.

    Google Scholar 

  13. Brown, A.E., Webster, H.K., Krinchai, K., Gordon, M., Wirtz, R.A., and Permpanich, B. 1991. Characteristics of natural antibody responses to the circumsporozoite protein of Plasmodium vivax. Am. J. Trop. Med. Hyg. 44:21–27.

    PubMed  CAS  Google Scholar 

  14. Bryan, J.H., and Coluzzi, M. 1971. Cytogenetic observations on Anopheles farauti Laveran. Bull. W.H.O. 45:266–267.

    PubMed  CAS  Google Scholar 

  15. Bryan, J.H., and Smalley, M.E. 1978. The use of ABO blood groups as markers for mosquito biting studies. Trans. R. Soc. Trop. Med. Hyg. 72:357–360.

    PubMed  CAS  Google Scholar 

  16. Burkot, T.R. 1988. Non-random host selection by anopheline mosquitoes. Parasitol. Today 4:156–162.

    PubMed  CAS  Google Scholar 

  17. Burkot, T.R., Dye, C., and Graves, P.M. 1989. An analysis of some factors affecting the sporozoite rates, human blood indexes and biting rates of the members of the Anopheles punctulatus complex in Papua New Guinea. Am. J. Trop. Med. Hyg. 40:229–234.

    PubMed  CAS  Google Scholar 

  18. Burkot, T., Garner, P., Paru, R., Dagoro, H., Barnes, A., McDougall, S., Wirtz, R.A., Campbell, G., and Spark, R. 1990. Effects of untreated bednets on the transmission of Plasmodium falciparum, P. vivax and Wuchereria bancrofti in Papua New Guinea. Trans. R. Soc. Trop. Med. Hyg. 84:773–779.

    CAS  Google Scholar 

  19. Burkot, T.R., Graves, P.M., Cattani, J.A., Wirtz, R.A., and Gibson, F.D. 1987. The efficiency of sporozoite transmission of the human malarias, Plasmodium falciparum and P. vivax. Bull. W.H.O. 65:375–380.

    PubMed  CAS  Google Scholar 

  20. Burkot, T.R., Graves, P.M., Paru, R., Battistutta, D., Barnes, A., and Saul, A. 1990. Variations in malaria transmission rates are unrelated to the anopheline survivorship per feeding cycle. Am. J. Trop. Med. Hyg. 43:321–327.

    PubMed  CAS  Google Scholar 

  21. Burkot, T.R., Graves, P.M., Paru, R., and Lagog, M. 1988. Mixed blood feeding by the malaria vectors in the Anopheles punctulatus complex (Diptera: Culicidae). J. Med. Entomol. 25:205–213.

    PubMed  CAS  Google Scholar 

  22. Burkot, T.R., Graves, P.M., Paru, R., Wirtz, R.A., and Heywood, P. 1988. Human malaria transmission studies in the Anopheles punctulatus complex in Papua New Guinea: Sporozoite rates, inoculation rates and sporozoite densities. Am. J. Trop. Med. Hyg. 39:135–144.

    PubMed  CAS  Google Scholar 

  23. Burkot, T.R., Graves, P.M., Wirtz, R.A., Brabin, B.J., Battistutta, D., Cattani, J.A., Maizels, R.M., and Alpers, M.P. 1989. Differential antibody responses to Plasmodium falciparum and P. vivax circumsporozoite proteins in a human population. J. Clin. Microbiol. 27:1346–1351.

    PubMed  CAS  Google Scholar 

  24. Burkot, T.R., Molineaux, L., Graves, P.M., Paru, R., Battistutta, D., Dagoro, H., Barnes, A., Wirtz, R.A., and Garner, P. 1990. The prevalence of naturally acquired multiple infections of Wuchereria bancrofti and human malarias in anophelines. Parasitology 100:369–375.

    PubMed  Google Scholar 

  25. Burkot, T.R., Narara, A., Paru, R., Graves, P.M., and Garner, P. 1989. Human host selection by anophelines: No evidence for preferential selection of malaria or microfilariae infected individuals in a hyperendemic area. Parasitology 98:337–342.

    PubMed  Google Scholar 

  26. Burkot, T.R., Williams, J.L., and Schneider, I. 1984. Detection of Plasmodium falciparum infected mosquitoes by a double antibody enzyme-linked immunosorbent assay. Am. J. Trop. Med. Hyg. 33:783–788.

    PubMed  CAS  Google Scholar 

  27. Burkot, T.R., Williams, J.L., and Schneider, I. 1984. Infectivity to mosquitoes of Plasmodium falciparum clones grown in vitro from the same isolate. Trans. R. Soc. Trop. Med. Hyg. 78:339–341.

    PubMed  CAS  Google Scholar 

  28. Burkot, T.R., and Wirtz, R.A. 1986. Immunoassays of malaria sporozoites in mosquitoes. Parasitol. Today 2:155–157.

    PubMed  CAS  Google Scholar 

  29. Burkot, T.R., Wirtz, R.A., Paru, R., Garner, P., and Alpers, M.P. 1992. The population dynamics in mosquitoes and humans of two Plasmodium vivax polymorphs distinguished by different circumsporozoite protein repeat regions. Am. J. Trop. Med. Hyg. 47:778–786.

    PubMed  CAS  Google Scholar 

  30. Burkot, T.R., Zavala, F., Gwadz, R.W., Collins, F., Nussenzweig, R.S., and Roberts, D.R. 1984. Identification of malaria-infected mosquitoes by a two-site enzyme linked immunosorbent assay. Am. J. Trop. Med. Hyg. 33:227–231.

    PubMed  CAS  Google Scholar 

  31. Burkot, T.R., Zhou, W.D., Geysen, H.M., Wirtz, R.A., and Saul, A. 1991. Fine specificities of monoclonal antibodies against the Plasmodium falciparum circumsporozoite protein: Recognition of both repetitive and non-repetitive regions. Parasite Immunol. 13:161–170.

    PubMed  CAS  Google Scholar 

  32. Carter, R., and Graves, P.M. 1988. Gametocytes. In W.H. Wernsdorfer and I. McGregor, eds., Malaria. Principles and Practices in Malariology, Vol. 1. Churchill Livingstone, Edinburgh, pp. 253–306.

    Google Scholar 

  33. Carter, R., and Gwadz, R.W. 1980. Infectiousness and gamete immunization in malaria. In J.P. Kreier, ed., Malaria, Volume 3, Immunology and Immunization. Academic Press, New York, pp. 263–298.

    Google Scholar 

  34. Carter, R., Kumar, N., Quakyi, I., Good, M., Mendis, K., Graves, P.M., and Miller, L. 1988. Immunity to sexual stages of malaria parasites. Prog. Allergy 41:193–214.

    PubMed  CAS  Google Scholar 

  35. Charlwood, J.D. 1986. Survival rate variation of Anopheles farauti (Diptera: Culicidae) between neighboring villages in coastal Papua New Guinea. J. Med. Entomol. 23:361–365.

    PubMed  CAS  Google Scholar 

  36. Charlwood, J.D., Birley, M.H., Dagoro, H., Paru, R., and Holmes, P.R. 1985. Assessing survival rates of Anopheles farauti (Diptera: Culicidae) from Papua New Guinea. J. Anim. Ecol. 54:1003–1016.

    Google Scholar 

  37. Charlwood, J.D., Graves, P.M., and Birley, M.H. 1986. Capture-recapture studies with mosquitoes of the group of Anopheles punctulatus Donitz (Diptera: Culicidae) from Papua New Guinea. Bull. Entomol. Res. 76:211–227.

    Google Scholar 

  38. Chege, G.M.M., and Beier, J.C. 1990. Effect of Plasmodium falciparum on the survival of naturally infected Afrotropical Anopheles (Diptera: Culicidae). J. Med. EntomoL 27:454–458.

    PubMed  CAS  Google Scholar 

  39. Clyde, D.F., and Shute, G.T. 1955. A technique for the investigation of mosquito feeding preferences on man. Trans. R. Soc. Trop. Med. Hyg. 49:64–67.

    PubMed  CAS  Google Scholar 

  40. Clyde, D.F., and Shute, G.T. 1958. Selective feeding habits of anophelines amongst Africans of different ages. Am. J. Trop. Med. Hyg. 7:543–545.

    PubMed  CAS  Google Scholar 

  41. Cochrane, A., Uni, S., Maracic, M., Di Giovanni, L., Aikawa, M., and Nussenzweig, R.S. 1989. A circumsporozoite protein is present in micronemes of mature blood stages of malaria parasites. Exp. Parasitol. 69:351–356.

    PubMed  CAS  Google Scholar 

  42. Collins, F.H., Mehaffey, P.C., Rasmussen, M.O., Brandling-Bennett, A.D., Odera, J.S., and Finnerty, V. 1988. Comparison of DNA-probe and isoenzyme methods for differentiating Anopheles gambiae and Anopheles arabiensis (Diptera: Culicidae). J. Med. EntomoL 25:116–120.

    PubMed  CAS  Google Scholar 

  43. Collins, F.H., Petrarca, V., Mpofu, S., Brandling-Bennett, A.D., Were, O., Rasmussen, M.O., and Finnerty, V. 1988. Comparison of DNA probe and cytogenetic methods for identifying field collected Anopheles gambiae complex mosquitoes. Am. J. Trop. Med. Hyg. 39:545–550.

    PubMed  CAS  Google Scholar 

  44. Collins, F.H., Sakai, R.K., Vernick, K.D., Paskewitz, S., Seeley, D.C., Miller, L.H., Collins, W.E., Campbell, C.C., and Gwadz, R.W. 1986. Genetic selection of a Plasmodium-refractory strain of the malaria vector Anopheles gambiae. Science 234:607–609.

    PubMed  CAS  Google Scholar 

  45. Collins, F.H., Zavala, F., Graves, P.M., Cochrane, A.H., Gwadz, R.W., Akoh, J., and Nussenzweig, R.S. 1984. First field trial of an immunoradiometric assay for the detection of malaria sporozoites in mosquitoes. Am. J. Trop. Med. Hyg. 33:538–543.

    PubMed  CAS  Google Scholar 

  46. Coluzzi, M. 1984. Heterogeneities of the malaria vectorial system in tropical Africa and their significance in malaria epidemiology and control. Bull. W.H.O. (Suppl.) 62:107–113.

    PubMed  Google Scholar 

  47. Conway, D.J., and McBride, J.S. 1991. Genetic evidence for the importance of interrupted feeding by mosquitoes in the transmission of malaria. Trans. R. Soc. Trop. Med. Hyg. 85:454–456.

    PubMed  CAS  Google Scholar 

  48. Cooper, L., Cooper, R.D., and Burkot, T.R. 1991. The Anopheles punctulatus complex: DNA probes for identifying the Australian species using isotopic, chromogenic, and chemiluminescence detection systems. Exp. Parasitol. 73:27–35.

    PubMed  CAS  Google Scholar 

  49. Coppel, R.L., Favaloro, J.M., Crewther, P.E., Burkot, T.R., Bianco, A.E., Stahl, H.D., Kemp, D.J., Anders, R.F., and Brown, G.V. 1985. A blood stage antigen of Plasmodium falciparum shares determinants with the sporozoite coat protein. Proc. Natl. Acad. Sci. U.S.A. 82:5121–5125.

    PubMed  CAS  Google Scholar 

  50. Covell, G. 1960. Relationship between malarial parasitaemia and symptoms of the disease. Bull. W.H.O. 22:605–619.

    PubMed  CAS  Google Scholar 

  51. Curtis, C.F., and Graves, P.M. 1983. Genetic variation in the ability of insects to transmit filariae, trypanosomes and malarial parasites. In K.F. Harris, ed., Current Topics in Vector Research. Praeger, New York, Vol. 1, pp. 31–62.

    Google Scholar 

  52. Day, J.F., Ebert, K.M., and Edman, J.D. 1983. Feeding patterns of mosquitoes (Diptera: Culicidae) simultaneously exposed to malarious and healthy mice, including a method for separating blood meals from conspecific hosts. J. Med. Entomol. 20:120–127.

    PubMed  CAS  Google Scholar 

  53. Day, J.F., and Edman, J.D. 1983. Malaria renders mice susceptible to mosquito feeding when gametocytes are most infective. J. Parasitol. 69: 163–170.

    PubMed  CAS  Google Scholar 

  54. Day, J.F., and Edman, J.D. 1984. The importance of disease induced changes in mammalian body temperature to mosquito blood feeding. Comp. Biochem. Physiol. 77A:447–452.

    Google Scholar 

  55. de Arruda, M., Carvalho, M.B., Nussenzweig, R.S., Maracic, M., Ferreira, A.W., and Cochrane, A.H. 1986. Potential vectors of malaria and their different susceptibility to Plasmodium falciparum and Plasmodium vivax in northern Brazil. Am. J. Trop. Med. Hyg. 35:873–881.

    PubMed  Google Scholar 

  56. de Zoysa, A.P.K., Mendis, C., Gamage-Mendis, A.C., Weerasinghe, S., Herath, P.R.J., and Mendis, K.N. 1991. A mathematical model for Plasmodium vivax malaria transmission: Estimation of the impact of transmission-blocking immunity in an endemic area. Bull. W.H.O. 69: 725–734.

    PubMed  Google Scholar 

  57. do Rosario, V.E., Appiah, A., Vaughan, J.A., and Hollingdale, M.R. 1989. Plasmocium falciparum: Administration of anti-sporozoite antibodies during sporogony results in production of sporozoites which are not neutralized by human anti-circumsporozoite protein vaccine sera. Trans. R. Soc. Trop. Hyg. 83:305–307.

    Google Scholar 

  58. Druilhe, P., Pradier, O., Marc, J.-P., Miltgen, F., Mazier, D., and Parent, G. 1986. Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection. Infect. Immun. 53:393–397.

    PubMed  CAS  Google Scholar 

  59. Dye, C. 1986. Vectorial capacity: Must we measure all its components? Parasitol. Today 2:203–209.

    PubMed  CAS  Google Scholar 

  60. Dye, C. 1990. Epidemiological significance of vector-parasite interactions. Parasitology 101:409–415.

    PubMed  Google Scholar 

  61. Dye, C. 1992. The analysis of parasite transmission by bloodsucking insects. Annu. Review Entomol. 37:1–19.

    CAS  Google Scholar 

  62. Dye, C., and Hasibeder, G. 1986. Population dynamics of mosquito-borne disease: Effects of flies which bite some people more frequently than others. Trans. R. Soc. Trop. Hyg. 80:69–77.

    CAS  Google Scholar 

  63. Edman, J., Day, J., and Walker, E. 1985. Vector-host interplay-factors affecting disease transmission. In L.P. Lounibos, J.R. Rey, and J.H. Frank, eds., Ecology of Mosquitoes. Chapman and Hall, New York, pp. 273–285.

    Google Scholar 

  64. Esposito, F., Lombardi, S., Modiano, D., Zavala., F., Reeme, J., Lamizana, L., Coluzzi, M., and Nussenzweig, R.S. 1988. Prevalence and levels of antibodies to the cireumsporozoite protein of Plasmodium falciparum in an endemic area and their relationship to resistance against malaria infection. Trans. R. Soc. Trop. Hyg. 82:827–832.

    CAS  Google Scholar 

  65. Feldmann, A.M., and Ponnudurai, T. 1989. Selection of Anopheles stephensi for refractoriness and susceptibility to Plasmodium falciparum. Med. Vet Entomol. 3:41–52.

    PubMed  CAS  Google Scholar 

  66. Fontes, C.C.J., Bathurst, I., and Krettli, A.U. 1991. Plasmodium vivax sporozoite antibodies in individuals exposed during a single malaria outbreak in a non-endemic area. Am. J. Trop. Med. Hyg. 44:28–33.

    PubMed  CAS  Google Scholar 

  67. Gale, K.R., and Crampton, J.M. 1987. DNA probes for species identification of mosquitoes in the Anopheles gambiae complex. Med. Vet. Entomol. 1:127–136.

    PubMed  CAS  Google Scholar 

  68. Gale, K.R., and Crampton, J.M. 1987. A DNA probe to distinguish the species Anopheles quadriannulatus from other species of the Anopheles gambiae complex. Trans. R. Soc. Trop. Med. Hyg. 81:842–846.

    PubMed  CAS  Google Scholar 

  69. Gamage-Mendis, A.C., Rajalaruna, J., Carter, R., and Mendis, K.N. 1991. Infectious reservoir of Plasmodium vivax and Plasmodium falciparum malaria in an endemic region of Sri Lanka. Am. J. Trop. Med. Hyg. 45:479–487.

    PubMed  CAS  Google Scholar 

  70. Garrett-Jones, C. 1964. The human blood index of malaria vectors in relation to epidemiological assessment. Bull. W.H.O. 30:241–261.

    PubMed  CAS  Google Scholar 

  71. Garrett-Jones, C., and Shidrawi, G.R. 1969. Malaria vectorial capacity of a population of Anopheles gambiae. An exercise in epidemiological entomology. Bull. W.H.O. 40:531–545.

    PubMed  CAS  Google Scholar 

  72. Gillies, M.T., and Wilkes, T.J. 1965. A study of the age-composition of populations of Anopheles gambiae Giles and A. funestus Giles in northeastern Tanzania. Bull. Entomol. Res. 56:237–262.

    PubMed  CAS  Google Scholar 

  73. Good, M.F., Saul, A., and Graves, P.M. 1992. Malaria. In Vaccines: New Approaches to Immunological Problems. Butterworths, London (in press).

    Google Scholar 

  74. Graves, P.M., Carter, R., Burkot, T.R., Quakyi, I.A., and Kumar, N. 1988. Antibodies to Plasmodium falciparum gamete surface antigens in Papua New Guinea sera. Parasite Immunol. 10:209–218.

    PubMed  CAS  Google Scholar 

  75. Graves, P.M., Burkot, T.R., Carter, R., Cattani, J.A., Lagog, M., Parker, J., Brabin, B.J., Gibson, F.D., Bradley, D.J., and Alpers, M.P. 1988. Measurement of malarial infectivity of human populations to mosquitoes in the Madang area, Papua New Guinea. Parasitology 96:251–263.

    PubMed  Google Scholar 

  76. Graves, P.M., Burkot, T.R., Saul, A., Hayes, R., and Carter, R. 1990. Estimation of anopheline survival rate, vectorial capacity, and mosquito infection probability from malaria vector infection rates in villages near Madang, Papua New Guinea. J. Appl. Ecol. 27:134–147.

    Google Scholar 

  77. Greenwood, B.M., Bradley, A.K., Greenwood, A.M., Byass, P., Jammeh, K., Marsh, K., Tulloch, S., Oldfield, F.S.J., and Hayes, R. 1987. Mortality and morbidity from malaria among children in a rural area of The Gambia, West Africa. Trans. R. Soc. Trop. Med. Hyg. 81:478–486.

    PubMed  CAS  Google Scholar 

  78. Greenwood, B., Marsh, K., and Snow, R. 1991. Why do some African children develop severe malaria?, Parasitol. Today 7:277–281.

    PubMed  CAS  Google Scholar 

  79. Herrington, D.A., Clyde, D.F., Losonsky, G., Cortesia, M., Murphy, J.R., Davis, J., Baqar, S., Felix, A.M., Heimer, E.P., Gillessen, D., Nardin, E., Nussenzweig, R.S., Nussenzweig, V., Hollingdale, M.R., and Levine, M.M. 1987. Safety and immunogenieity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites. Nature (London) 328:257–259.

    CAS  Google Scholar 

  80. Hii, J.L.K., Birley, M.H., and Sang, V.Y. 1990. Estimation of survival rate and oviposition interval of Anopheles balabacensis mosquitoes from mark-recapture experiments in Sabah, Malaysia. Med. Vet. Entomol. 4:135–140.

    PubMed  CAS  Google Scholar 

  81. Hii, J.L.K., Chew, M., Sang, V.Y., Munstermann, L.E., Tan, S.G., Panyim, S., and Yasothornsrikul, S. 1991. Population genetic analysis of host seeking and resting behaviors in the malaria vector, Anopheles balabacensis (Diptera: Culicidae). J. Med. Entomol. 28:675–684.

    PubMed  CAS  Google Scholar 

  82. Hill, S.M., Urwin, R., and Crampton, J.M. 1991. A comparison of nonradioactive labeling and detection systems with synthetic oligonucleotide probes for the species identification of mosquitoes in the Anopheles gambiae complex. Am. J. Trop. Med. Hyg. 44:609–622.

    PubMed  CAS  Google Scholar 

  83. Hill, A.V.S., Allsopp, C.E.M., Kwiatkowski, D., Anstey, N.M., Twumasi, P., Rowe, P.A., Bennett, S., Brewster, D., McMichael, A.J., and Greenwood, B.M. 1991. Common West African HLA antigens are associated with protection from severe malaria. Nature (London) 352:595–600.

    CAS  Google Scholar 

  84. Hollingdale, M.R., and do Rosario, V. 1989. Malaria transmission-enhancing activity in mosquitoes by mammalian host anti-sporozoite antibodies. Exp. Parasitol. 68:365–368.

    PubMed  CAS  Google Scholar 

  85. Holmes, P.R., and Birley, M.H. 1987. An improved method for survival rate analysis from time series of haematophagous dipteran populations. J. Anim. Ecol. 56:427–440.

    Google Scholar 

  86. Hope, I.A., Hall, R., Simmons, D.U., Hyde, J.E., and Scaife, J.G. 1984. Evidence for immunological cross-reaction between sporozoites and blood stages of a human malaria parasite. Nature (London) 308:191–194.

    CAS  Google Scholar 

  87. Ijumba, J.N., Mwangi, R.W., and Beier, J.C. 1990. Malaria transmission potential of Anopheles mosquitoes in the Mwea-Tebere irrigation scheme, Kenya. Med. Vet. Entomol. 4:425–432.

    PubMed  CAS  Google Scholar 

  88. Jeffery, G.M., Young, M.D., Burgess, R.W., and Eyles, D.E. 1959. Early activity in sporozoite-induced Plasmodium falciparum infections. Ann. Trop. Med. Parasitol. 54:51–58.

    Google Scholar 

  89. Kelly, R., and Edman, J.D. 1992. Multiple transmission of Plasmodium gallinaceum (Eucoccida: Plasmodiidae) during serial probing by Aedes aegypti (Diptera: culicidae) on several hosts. J. Med. Entomol. 29:329–331.

    PubMed  CAS  Google Scholar 

  90. Kingsolver, J.G. 1987. Mosquito host choice and the epidemiology of malaria. Am. Nat. 130:811:-827.

    Google Scholar 

  91. Kitthawee, S., Edman, J.D., and Sattabongkot, J. 1990. Evaluation of survival potential and malaria susceptibility among different size classes of laboratory-reared Anopheles dirus. Am. J. Trop. Med. Hyg. 43:328–332.

    PubMed  CAS  Google Scholar 

  92. Klein, T.A., Harrison, B.A., Grove, J.S., Dixon, S.V., and Andre, R.G. 1986. Correlation of survival rates of Anopheles dirus A (Diptera: Culicidae) with different infection densities of Plasmodium cynomolgi. Bull. W.H.O. 64:901–907.

    PubMed  CAS  Google Scholar 

  93. Klein, T.A., Lima, J.B.P., Tada, M.S., and Miller, R. 1991. Comparative susceptibility of Anopheline mosquitoes in Rondonia, Brazil to infection by Plasmodium vivax. Am. J. Trop. Med. Hyg. 45:463–470.

    PubMed  CAS  Google Scholar 

  94. Klein, T.A., Tada, M.S., Lima, J.B.P., and Katsuragawa, T.H. 1991. Infection of Anopheles darlingi fed on patients infected with Plasmodium vivax before and during treatment with chloroquine in Costa Marques, Rondonia, Brazil. Am. J. Trop. Med. Hyg. 45:471–478.

    PubMed  CAS  Google Scholar 

  95. Klein, T.A., Tada, M.S., and Lima, J.B.P. 1991. Infection of Anopheles darlingi fed on patients with Plasmodium falciparum before and after treatment with quinine or quinine plus tetracycline. Am. J. Trop. Med. Hyg. 44:604–608.

    PubMed  CAS  Google Scholar 

  96. Lepers, J.P., Fontenille, D., Rason, M.D., Chougnet, C., Astagneau, P., Coulanges, P., and DeLoron, P. 1991. Transmission and epidemiology of newly transmitted falciparum malaria in the central highland plateaux of Madagascar. Ann. Trop. Med. Parasitol. 85:297–304.

    PubMed  CAS  Google Scholar 

  97. Lindsay, S.W., Snow, R.W., Broomfield, G., Semega Janneh, M., Wirtz, R.A., and Greenwood, B.M. 1989. Impact of permethrin treated bed-nets on malaria transmission in The Gambia. Med. Vet. Entomol. 3:263–271.

    PubMed  CAS  Google Scholar 

  98. Lindsay, S.W., Wilkins, H.A., Zieler, H.A., Daly, R.J., Petrarca, V., and Byass, P. 1991. Ability of Anopheles gambiae mosquitoes to transmit malaria during the dry and wet seasons in an area of irrigated rice cultivation in The Gambia. J. Trop. Med. Hyg. 94:313–324.

    PubMed  CAS  Google Scholar 

  99. Lines, J.D., Curtis, CF., Wilkes, T.J., and Hjunwa, K.J. 1991. Monitoring human biting mosquitoes in Tanzania with light traps hung beside mosquito nets. Bull. Entomol. Res. 81:77–84.

    Google Scholar 

  100. Lines, J.D., Wilkes, T.J., and Lyimo, E.O. 1991. Human malaria infectiousness measured by age-specific sporozoite rates in Anopheles gambiae in Tanzania. Parasitology 102:167–177.

    PubMed  Google Scholar 

  101. Lombardi, S., Esposito, F., Zavala, F., Lamizana, L., Rossi, P., Sabatinelli, G., Nussenzweig, R.S., and Coluzzi, M. 1987. Detection and anatomical localization of Plasmodium falciparum circumsporozoite protein and sporozoites in the afrotropical malaria vector Anopheles gambiae s.l. Am. J. Trop. Med. Hyg. 37:491–494.

    PubMed  CAS  Google Scholar 

  102. Ma, M., Beier, J.C., Petrarca, V., Gwadz, R.W., Zhang, J.-Z., Song, Q., and Koech, D.K. 1990. Differentiation of Anopheles gambiae and An. arabiensis (Diptera: Culicidae) by ELISA using immunoaffinity purified antibodies to vitellogenin. J. Med. Entomol. 27:564–569.

    PubMed  CAS  Google Scholar 

  103. MacCormack, C.P. 1984. Human ecology and behaviour in malaria control in tropical Africa. Bull. W.H.O. 62 (Suppl.):81–87.

    PubMed  Google Scholar 

  104. Macdonald, G. 1957. The Epidemiology and Control of Malaria, Oxford University Press, London.

    Google Scholar 

  105. Magesa, S.M., Wilkes, T.J., Mnzava, A.E.P., Njunwa, K.J., Myamba, J., Kivuyo, M.D.P., Hill, N., Lines, J.D., and Curtis, C.F. 1991. Trial of pyrethroid impregnated bednets in an area of Tanzania holoendemic for malaria. Part 2. Effects on the malaria vector population. Acta Tropica 49:97–108.

    PubMed  CAS  Google Scholar 

  106. Malik, A., Egan, J.E., Houghten, R.A., Sadoff, J.C., and Hoffman, S.L. 1991. Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. Proc. Natl. Acad. Sci. U.S.A. 88:3300–3304.

    PubMed  CAS  Google Scholar 

  107. Mattei, D., Berzins, K., Wahlgren, M., Udomsangpetch, R., Perlmann, P., Griesser, H.W., Scherf, A., Muller-Hill, B., Bonnefoy, S., Guillotte, M., Langsley, G., Pereira da Silva, L., and Mercereau-Puijalon, O. 1989. Cross-reactive antigenic determinants present on different Plasmodium fal ciparum blood-stage antigens. Parasite Immunol. 11:15–30.

    PubMed  CAS  Google Scholar 

  108. McGregor, I.A., and Wilson, R.J.M., 1988. Specific immunity: acquired in man, Wernsdorfer, W.H., and McGregor, I. (eds). In Malaria. Principles and Practices in Malariology, Vol. 1. Churchill Livingstone, Edinburgh, pp. 253–306.

    Google Scholar 

  109. Mellouk, S., Mazier, D., Druilhe, P., Berbiguier, N., and Danis, M. 1986. In vitro and in vivo results suggesting that anti-sporozoite antibodies do not totally block Plasmodium falciparum sporozoite infectivity. N. Engl. J. Med. 315:648.

    PubMed  CAS  Google Scholar 

  110. Mendis, C., Del Giudice, G., Gamage-Mendis, A.C., Tougne, C., Pessi, A., Weerasinghe, S., Carter, R., and Mendis, K.N. 1992. Anti-circumsporozoite protein antibodies measure age related exposure to malaria in Kataragama, Sri Lanka. Parasite Immunol. 14:75–86.

    PubMed  CAS  Google Scholar 

  111. Mendis, K.N., Munesinghe, Y.D., de Silva, Y.N.Y., Keragalla, I., and Carter, R. 1987. Malaria transmission-blocking immunity induced by natural infections of Plasmodium vivax in humans. Infect. Immun. 55:369–372.

    PubMed  CAS  Google Scholar 

  112. Mendis, K.N., Naotunne, T., Naotunne de, S., Karunaweera, N.D., Del Giudice, G., Grau, G.E., and Carter, R. 1990. Anti-parasite effects of cytokines in malaria. Immunol. Lett. 25:217–220.

    PubMed  CAS  Google Scholar 

  113. Metselaar, D. 1960. Relative increase in the prevalence of Plasmodium falciparum some years after the beginning of a house-spraying campaign in Netherlands New Guinea. Trans. R. Soc. Trop. Hyg. 54:523–528.

    CAS  Google Scholar 

  114. Moelans, I.I.M.D., Meis, J.F.G.M., Kocken, C., Konings, R.N.H., and Schoenmakers, J.G.G. 1991. A novel protein antigen of the malaria parasite Plasmodium falciparum, located on the surface of gametes and sporozoites. Mol. Biochem. Parasitol. 45:193–204.

    PubMed  CAS  Google Scholar 

  115. Molineaux, L., and Gramiccia, G. 1980. The Garki Project: Research on the Epidemiology and Control of Malaria in the Sudan Savanna of West Africa. W.H.O., Geneva, pp. 255–259.

    Google Scholar 

  116. Muirhead-Thompson, R.C. 1951. The distribution of Anopheline mosquito bites among different age groups. Br. Med. J. 1:1114–1117.

    Google Scholar 

  117. Muirhead-Thompson, R.C. 1957. The malaria infectivity of an African village population to mosquitoes (Anopheles gambiae). Am. J. Trop. Med. Hyg. 6:971–979.

    Google Scholar 

  118. Naotunne, T., De, S., Karunaweera, N.D., Del Giudice, G., Kularatne, M.U., Grau, G.E., Carter, R., and Mendis, K.N. 1991. Cytokines kill malaria parasites during infection crisis: extracellular complementary factors are essential. J. Exp. Med. 173:523–529.

    PubMed  CAS  Google Scholar 

  119. Naotunne, T., De, S., Rathnayake, K.D.L., Jayasinghe, A., Carter, R., and Mendis, K.N. 1990. Plasmodium cynomolgi: Serum-mediated blocking and enhancement of infectivity to mosquitoes during infections in the natural host. Macaca sinica. Exp. Parasitol. 71:305–313.

    CAS  Google Scholar 

  120. Nardin, E.H., Nussenzweig, R.A., McGregor, I.A., and Bryan, J.H. 1979. Antibodies to sporozoites: Their frequent occurrence in individuals living in an area of hyperendemic malaria. Science 206:597–599.

    PubMed  CAS  Google Scholar 

  121. Nedelman, J. 1989. Gametocytemia and infectiousness in falciparum malaria: Observations and models. In K.F. Harris, ed., Advances in Disease Vector Research, Vol. 6. Springer-Verlag, New York, pp. 59–89.

    Google Scholar 

  122. Nudelman, S., Renia, L., Charoenvit, Y., Yuan, L., Miltgen, F., Beaudoin, R.L., and Mazier, D. 1989. Dual action of anti-sporozoite antibodies in vitro. J. Immunol. 143:996–1000.

    PubMed  CAS  Google Scholar 

  123. Panyim, S., Yasothornsrikul, S., Tungprodubkul, S., Baimai, V., Rosenberg, R., Andre, R.G., and Green, C.A. 1988. Identification of isomorphic malaria vectors using a DNA probe. Am. J. Trop. Med. Hyg. 38:47–49.

    PubMed  CAS  Google Scholar 

  124. Peiris, J.S.M., Premawansa, S., Ranawaka, M.B.R., Udagama, P.V., Munasinghe, Y.D., Nanayakkara, M.V., Gamage, C.P., Carter, R., David, P.H., and Mendis, K.N. 1988. Monoclonal and polyclonal antibodies both block and enhance transmission of human Plasmodium vivax malaria. Am. J. Trop. Med. Hyg. 39:26–32.

    PubMed  CAS  Google Scholar 

  125. Petersen, E., Hogh, B., Marbiah, N.T., David, K., and Hanson, A.P. 1991. Development of immunity against Plasmodium falciparum malaria: Clinical and parasitologic immunity cannot be separated. J. Infect. Dis. 164:949–953.

    PubMed  CAS  Google Scholar 

  126. Petrarca, V., and Beier, J.C. 1992. Intraspecific chromosomal polymorphism in the Anopheles gambiae complex as a factor affecting malaria transmission in the Kisumu area of Kenya. Am. J. Trop. Med. Hyg. 46:229–237.

    PubMed  CAS  Google Scholar 

  127. Ponnudurai, T., Billingsley, P.F., and Rudin, W. 1988. Differential infectivity of Plasmodium for mosquitoes. Parasitol. Today 4:319–321.

    PubMed  CAS  Google Scholar 

  128. Ponnudurai, T., Lensen, A.H.W., van Gemert, G.J.A., Bensing, M.P.E., Bolmer, M., and Meuweissen, J.H.E.Th. 1979. Sporozoite load of mosquitoes infected with Plasmodium falciparum. Trans. R. Soc. Trop. Med. Hyg. 83:67–70.

    Google Scholar 

  129. Port, G.R., Boreham, P.F.L., and Bryan, J.H. 1980. The relationship of host size to feeding by mosquitoes of the Anopheles gambiae Giles complex (Diptera: Culicidae). Bull. Entomol. Res. 70:133–144.

    Google Scholar 

  130. Porter, C.H., and Collins, F.H. 1991. Species-diagnostic differences in a ribosomal DNA internal transcribed spacer from the sibling species Anopheles freeborni and Anopheles hermsi (Diptera: Culicidae). Am. J. Trop. Med. Hyg. 45:271–279.

    PubMed  CAS  Google Scholar 

  131. Porter, R.J., Laird, R.L., and Dusseau, E.M. 1954. Studies on malarial sporozoites. II. Effect of age and dosage of sporozoites on their infectiousness. Exp. Parasitol. 3:267–274.

    PubMed  CAS  Google Scholar 

  132. Ranawaka, M.B., Munesinghe, Y.D., de Silva, D.M.R., Carter, R., and Mendis, K.N. 1988. Boosting of transmission-blocking immunity during natural Plasmodium vivax infections in humans depends upon frequent reinfection. Infect. Immun. 56:1820–1824.

    PubMed  CAS  Google Scholar 

  133. Relf, W.A., Pugh, R.E., Tapchaisri, P., Khusmith, S., Healey, A., Upcroft, P., Tharavanij, S., and Kidson, C. 1990. Diagnosis of Plasmodium vivax malaria using a specific deoxyribonucleic acid probe. Trans. R. Soc. Trop. Med. Hyg. 84:630–634.

    PubMed  CAS  Google Scholar 

  134. Ribeiro, J.M.C., Rossignol, P.A., and Spielman, A. 1985. Salivary gland apyrase determines probing time in anopheline mosquitoes. J. Insect Physiol. 31:689–692.

    CAS  Google Scholar 

  135. Rickman, L.S., Jones, T.R., Long, G.W., Paparello, S., Schneider, I., Paul, C.F., Beaudoin, R.L., and Hoffman, S.L. 1990. Plasmodium falciparum-infected Anopheles stephensi inconsistently transmit malaria to humans. Am. J. Trop. Med. Hyg. 43:441–445.

    PubMed  CAS  Google Scholar 

  136. Robert, V., Verhave, J.P., and Carnevals, P. 1990. Plasmodium falciparum infection does not increase the precocious mortality rate of Anopheles gambiae. Trans. R. Soc. Trop. Med. Hyg. 84:346–347.

    PubMed  CAS  Google Scholar 

  137. Robert, V., Verhave, J.P., Ponnudurai, T., Louwe, L., Scholtens, P., and Carnevale, P. 1988. Study of the distribution of circumsporozoite antigen in Anopheles gambiae infected with Plasmodium falciparum, using the enzyme-linked immunosorbent assay. Trans. R. Soc. Trop. Med. Hyg. 82:389–391.

    PubMed  CAS  Google Scholar 

  138. Rosenberg, R. 1985. Inability of Plasmodium knowlesi sporozoites to invade Anopheles freeborni salivary glands. Am. J. Trop. Med. Hyg. 34:687–691.

    PubMed  CAS  Google Scholar 

  139. Rosenberg, R., Andre, R.G., and Ketrangsee, S. 1990. Seasonal fluctuation of Plasmodium falciparum gametocytaemia. Trans. R. Soc. Trop. Med. Hyg. 84:29–33.

    PubMed  CAS  Google Scholar 

  140. Rosenberg, R., Andre, R.G., and Somchit, L. 1990. Highly efficient dry season transmission of malaria in Thailand. Trans. R. Soc. Trop. Med. Hyg. 84:22–28.

    PubMed  CAS  Google Scholar 

  141. Rosenberg, R., and Rungsiwongse, J. 1991. The number of sporozoites produced by individual malaria oocysts. Am. J. Trop. Med. Hyg. 45:574–577.

    PubMed  CAS  Google Scholar 

  142. Rosenberg, R., Wirtz, R.A., Lanar, D.E., Sattabongkot, J., Hall, T., Waters, A.P., and Prasittisuk, C. 1989. Circumsporozoite protein heterogeneity in the human malaria parasite Plasmodium vivax. Science 245:973–976.

    PubMed  CAS  Google Scholar 

  143. Rosenberg, R., Wirtz, R.A., Schneider, I., and Burge, R. 1990. An estimation of the number of malaria sporozoites ejected by a feeding mosquito. Trans. R. Soc. Trop. Med. Hyg. 84:209–212.

    PubMed  CAS  Google Scholar 

  144. Rossignol, P.A., Ribeiro, J.M.C., Jungery, M., Spielman, A., and Bailey, C.L. 1985. Enhanced mosquito blood-finding success on parasitemic hosts: Evidence for vector-parasite mutualism. Proc. Natl. Acad. Sci. U.S.A. 82:7725–7727.

    PubMed  CAS  Google Scholar 

  145. Rossignol, P.A., Ribeiro, J.M.C., and Spielman, A. 1984. Increased intradermal probing time in sporozoite-infected mosquitoes. Am. J. Trop. Med. Hyg. 33:17–20.

    PubMed  CAS  Google Scholar 

  146. Rozendaal, J.A. 1989. Impregnated mosquito nets and curtains for self protection and vector control. Trop. Dis. Bull. 86:R1–R41.

    Google Scholar 

  147. Sattabongkot, J., Maneechai, N., and Rosenberg, R. 1991. Plasmodium vivax: Gametocyte infectivity of naturally infected Thai adults. Parasitology 102:27–31.

    PubMed  Google Scholar 

  148. Saul, A. 1987. Estimation of survival rates and population size from mark-release-recapture experiments of bait-caught haematophagous insects. Bull. Entomol. Res. 77:589–602.

    Google Scholar 

  149. Saul, A., Graves, P.M., and Kay, B.H. 1990. A cyclical feeding model for pathogen transmission and its application to determine vectorial capacity from vector infection rates. J. Appl. Ecol. 27:123–133.

    Google Scholar 

  150. Schmidt, L.H., Fradkin, R., Genther, C.S., Rossan, R.N., and Squires, W. 1982. I. The characteristics of untreated sporozoite-induced and trophozoite-induced infections. Am. J. Trop. Med. Hyg. 31 (Suppl.):612–645.

    Google Scholar 

  151. Turrell, M.J., and Spielman, A. 1992. Nonvascular delivery of Rift Valley fever virus by infected mosquitoes. Am. J. Trop. Med. Hyg. 47:190–194.

    Google Scholar 

  152. Ungureanu, E., Killiek-Kendrick, R., Gamham, P.C.C., Branzei, P., Romanescu, C., and Shute, P.G. 1976. Prepaient periods of a tropical strain of Plasmodium vivax after inoculations of tenfold dilutions of sporozoites. Trans. R. Soc. Trop. Med. Hyg. 70:482–483.

    PubMed  CAS  Google Scholar 

  153. Vanderberg, J.P. 1977. Plasmodium berghei: Quantitation of sporozoites injected by mosquitoes feeding on a rodent host. Exp. Parasitol. 42:169–181.

    PubMed  CAS  Google Scholar 

  154. Vaughan, J.A., and Azad, A.F. 1988. Passage of host immunoglobulin G from blood meal into hemolymph of selected mosquito species (Diptera: Culicidae). J. Med. Entomol. 25:472–474.

    PubMed  CAS  Google Scholar 

  155. Vaughan, J.A., Do Rosario, V., Leland, P., Adjepong, A., Light, J., Woollett, G.R., Hollingdale, M.R., and Azad, A.F. 1988. Plasmodium falciparum: Ingested anti-sporozoite antibodies affect sporogony in Anopheles stephensi mosquitoes. Exp. Parasitol. 66:171–182.

    PubMed  CAS  Google Scholar 

  156. Vernick, K.D., Collins, F.H., and Gwadz, R.W. 1989. A general system of resistance to malaria infection in Anopheles gambiae controlled by two main genetic loci. Am. J. Trop. Med. Hyg. 40:585–592.

    PubMed  CAS  Google Scholar 

  157. Ward, R.A. 1963. Genetic aspects of the susceptibility of mosquitoes to malarial infection. Exp. Parasitol. 13:328–341.

    Google Scholar 

  158. Waters, A.P., and McCutchan, T.F. 1989. Ribosomal RNA: nature’s own polymerase-amplified target for diagnosis. Parasitol. Today 6:56–59.

    Google Scholar 

  159. Webster, H.K., Boudreau, E.F., Pang, L.W., Permpanich, B., Sookto, P., and Wirtz, R.A. 1987. Development of immunity in natural Plasmodium falciparum malaria: Antibodies to the falciparum sporozoite vaccine 1 antigen (R32tet32). J. Clin. Microbiol. 25:1002–1008.

    PubMed  CAS  Google Scholar 

  160. Wirtz, R.A., and Burkot, T.R. 1991. Detection of malarial parasites in mosquitoes. In K.F. Harris, ed. Advances in Disease Vector Research, Vol. 8. Springer-Verlag, New York, pp. 77–106.

    Google Scholar 

  161. Wirtz, R.A., Burkot, T.R., Andre, R.G., Rosenberg, R.M., Collins, W.E., and Roberts, D.R. 1985. Identification of Plasmodium vivax sporozoites in mosquitoes using an enzyme-linked immunosorbent assay. Am. J. Trop. Med. Hyg. 34:1048–1054.

    PubMed  CAS  Google Scholar 

  162. Wirtz, R.A., Burkot, T.R., Graves, P.M., and Andre, R.G. 1987. Field evaluation of enzyme-linked immunosorbent assays for Plasmodium falciparum and Plasmodium vivax sporozoites in mosquitoes (Diptera: Culicidae) from Papua New Guinea. J. Med. Entomol. 24:433–437.

    PubMed  CAS  Google Scholar 

  163. Wirtz, R.A., Charoenvit, Y., Burkot, T.R., Esser, K.M., Beaudoin, R.L., Collins, W.E., Rosenberg, R., and Andre, R.G. 1990. Evaluation of monoclonal antibodies against Plasmodium vivax sporozoites for ELISA development. Med. Vet. Entomol. 5:17–22.

    Google Scholar 

  164. Wirtz, R.A., Duncan, J.F., Njelesani, E.K., Schneider, I., Brown, A.E., Oster, C.N., Were, J.B.O., and Webster, H.K. 1989. ELISA method for detecting Plasmodium falciparum circumsporozoite antibody. Bull. W.H.O. 67:535–542.

    PubMed  CAS  Google Scholar 

  165. Wirtz, R.A., Sattabongkot, J., Hall, T., Burkot, T.R., and Rosenberg, R. 1992. Development and evaluation of an ELISA for Plasmodium vivax variant strain-VK247 sporozoites. J. Med. Entomol. 29:854–857.

    PubMed  CAS  Google Scholar 

  166. Wirtz, R.A., Zavala, F., Charoenvit, Y., Campbell, G.H., Burkot, T.R., Schneider, I., Esser, K.M., Beaudoin, R.L., and Andre, R.G. 1987. Comparative testing of Plasmodium falciparum sporozoite monoclonal antibodies for ELISA development. Bull. W.H.O. 65:39–45.

    PubMed  CAS  Google Scholar 

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Burkot, T.R., Graves, P.M. (1994). Human Malaria Transmission: Reconciling Field and Laboratory Data. In: Harris, K.F. (eds) Advances in Disease Vector Research. Advances in Disease Vector Research, vol 10. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2590-4_6

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