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Immunological Regulation of Endometrial Function: Cytokine Production in the Human Endometrium

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Molecular and Cellular Aspects of Periimplantation Processes

Part of the book series: Serono Symposia USA ((SERONOSYMP))

Abstract

The physiological functions of various organs and tissues are thought to be regulated by a paracrine system employing a number of growth factors and cytokines, as well as by the nerve and endocrine systems. Recently, a reciprocal relationship between endocrine and immune functions has become apparent in the female reproductive system with respect to ovarian and uterine functions. Furthermore, a number of cytokines have been identified that are produced in the female reproductive organs. Of the various cytokines known to be produced in the uterus, it is suggested that macrophage colony stimulating factor (M-CSF) (1, 2), stem cell factor (SCF) (3, 4), leukemia inhibitory factor (LIF) (5, 6), and transforming growth factor β (TGFβ) (7)are thought to stimulate or suppress local immune cell function and play important roles in blastocyst implantation and/or early placental development.

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Authors
  1. Hideharu Kanzaki
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  2. Takahide Mori
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Editor information

Editors and Affiliations

  1. Department of Physiology, University of Kansas Medical Center, Kansas City, KS, 66160, USA

    S. K. Dey Ph.D.

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© 1995 Springer-Verlag New York, Inc.

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Kanzaki, H., Mori, T. (1995). Immunological Regulation of Endometrial Function: Cytokine Production in the Human Endometrium. In: Dey, S.K. (eds) Molecular and Cellular Aspects of Periimplantation Processes. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2548-5_19

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  • DOI: https://doi.org/10.1007/978-1-4612-2548-5_19

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7575-6

  • Online ISBN: 978-1-4612-2548-5

  • eBook Packages: Springer Book Archive

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