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Abstract

By definition, plasma substitutes aim to replace a fluid which is colloidal in nature by virtue of its content of different species of highly specialized proteins. In plasma, albumin is present in the highest concentration and has the highest colloid osmotic power of all the plasma proteins.

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References

  1. Aberg M, Hedner U, Bergentz SE (1978) Effect of dextran on factor VIII (antihemophilic factor). Ann Surg 189: 243–247

    Article  Google Scholar 

  2. Alving BM, Hojima J, Pisano JJ, Mason BL, Buckingham RE, Mozen MM, Finlayson JS (1978) Hypotension associated with prekallikrein activator ( Hageman Factor Fragments) in plasma protein fraction. N Engl J Med 299: 66–70

    Google Scholar 

  3. Beez M, Diet] H (1979) Retrospektive Betrachtungen der Häufigkeit anaphylaktoider Reaktionen nach PlasmasterilR und LongasterilR. Infusionstherapie 6: 23–26

    CAS  Google Scholar 

  4. Boon JC, Jesch F, Ring J, Messmer K (1976) Intravascular persistence of hydroxyethyl starch in man. Eur Surg Res 8: 497–503

    Article  PubMed  CAS  Google Scholar 

  5. Collins JA, Larcan A, Litwin MS, Lutz H, Ring J, Thorén, L, Tschirren B (1979) To which extent is the clinical use of dextran, gelatin and hydroxyethyl starch influenced by the incidence and severity of anaphylactoid reactions? ( International Forum ). Vox Sang 36: 39

    Google Scholar 

  6. Colman RW (1978) Paradoxical hypotension after volume expansion with plasma protein fractions. N Engl J Med 299: 97–98

    Article  PubMed  CAS  Google Scholar 

  7. Combridge DS, Wesley ED (1979) Plasma protein fraction: the disappearance of kinin from the solution on storage. Transfusion 19: 599–600

    Article  PubMed  CAS  Google Scholar 

  8. Gruber UF (1969) Blood replacement. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  9. Gruber UF (1975) Dextran and the prevention of postoperative thromboembolic complications. Surg Clin North Am 55: 679–696

    PubMed  CAS  Google Scholar 

  10. Gruber UF, Sturm V, Messmer K (1976) Fluid replacement in shock. In: Ledingham I McA (ed) Shock, clinical and experimental aspects. Excerpta Medica/American Elsevier, Amsterdam, p 231–256

    Google Scholar 

  11. Gruber UF, Saldeen T, Brokop T, Eklöf B, Erikson J, Goldie I, Gran L, Hohl M, Jonsson T, Kristersson S, Ljungström KG, Lund T, Maartman Moe H, Svensjö E, Thomson D, Torhorst I, Trippestad A, Ulstein M (1980) Comparison of the incidence of fatal pulmonary embolism with dextran 70 and low dose heparin prophylaxis. An international multicenter trial. Br Med J 280: 69–72

    Google Scholar 

  12. Harke H, Pieper C, Meredig I, Rahman S, Rüssler P (1980) Rheological and clotting investigations after the infusion of HES 200/0.5 and dextran 40. Anaesthesist 29: 71–77

    PubMed  CAS  Google Scholar 

  13. Isbister JP, Fisher M McD (1980) Adverse effects of plasma volume expanders. Anaesth Intensive Care 8: 145–151

    CAS  Google Scholar 

  14. Jesch F, Kloevekorn WP, Sunder-Plassmann L, Seifert J, Messmer K (1975) Hydroxyläthylstärke als Plasmaersatzmittel. Untersuchungen mit isovolämischer Hämodilution. Anaesthesist 24: 202–209

    Google Scholar 

  15. Köhler H, Kirch W, Weihrauch TR, Prellwitz W, Horstmann HJ (1977) Macroamylasemia after treatment with hydroxylethyl starch. Eur J Clin Invest 7: 205–211

    Article  PubMed  Google Scholar 

  16. Laubenthal H, Peter K, Hedin H, Richter W, Messmer K (1980) Specific hapten inhibition for prevention of dextran-induced anaphylactoid reactions. Clinical results. Europ Surg Res 12 [Suppl 11: 68–69

    Google Scholar 

  17. Lorenz W, Doenicke A, Dittmann I, Hug P, Schwarz B (1977) Anaphylactoid reactions following administration of plasma substitutes in man. Prevention of side-effects of Haemaccel by premedication with H,- and H2-receptor antagonists. Anaesthesist 26: 644–648

    PubMed  CAS  Google Scholar 

  18. Lundsgaard-Hansen P, Tschirren B (1978) Modified fluid gelatin as a plasma substitute. Prog Clin Biol Res 19: 227–257

    PubMed  CAS  Google Scholar 

  19. Lutz H (1980) Plasmaersatzmittel, 3rd edn. Thieme, Stuttgart New York

    Google Scholar 

  20. McMillin RD, Hood TR, Griffen WO (1978) Systemic anaphylaxis secondary to the use of 5 percent plasma protein fractions. Am J Surg 135: 706–707

    Article  PubMed  CAS  Google Scholar 

  21. Messmer K (1975) Hemodilution. Surg Clin North Am 55: 659–678

    CAS  Google Scholar 

  22. Messmer K, Jesch F (1978) Volumenersatz und Hämodilution durch Hydroxyäthylstärke. Infusionstherapie 5: 169–173

    CAS  Google Scholar 

  23. Messmer K, Ljungström KG, Gruber UF, Richter W, Hedin H (1980a) Prevention of dextran-induced anaphylactoid reactions by hapten inhibition. Lancet I: 975

    Google Scholar 

  24. Messmer K, Seemann C, Hedin H, Richter W, Peter K (1980b) Anaphylaktoide Reaktionen nach Dextran: II) Tierexperimentelle und klinische Ergebnisse der Prophylaxe durch Hapten-Hemmung. Allergologie 3: 59–66

    Google Scholar 

  25. Richter W, Hedin H, Ring J, Kraft D, Messmer K (1980a) Anaphylaktoide Reaktionen nach Dextran: I) Immunologische Grundlagen und klinische Befunde. Allergologie 3: 51–58

    Google Scholar 

  26. Richter W, Hedin H, Messmer K (1980b) Ist die Haptenhemmung bei der Infusion von Dextranlösungen wirksam? Anaesthesist 29: 444–445

    PubMed  CAS  Google Scholar 

  27. Ring J (1978) Anaphylactoid reactions. Springer, Berlin Heidelberg New York (Anesthesiology and intensive care medicine, vol 111 )

    Google Scholar 

  28. Ring J, Messmer K (1977) Incidence and severity of anaphylactoid reactions to colloid volume substitutes. Lancet I: 466–469

    Article  Google Scholar 

  29. Ring J, Richter W (1980) Wirkungsmechanismus unerwünschter Reaktionen nach Hydroyäthylstärke ( HAS) und Humanalbumin. Allergologie 3: 79–86

    CAS  Google Scholar 

  30. Shires GT, Bergentz SE, Gruber UF, Baxter Ch, Moss GS (1980) Colloids or not for resuscitation? In: Allgöwer M, Harder F (eds) State of the art of surgery 1979/80. Springer, Berlin Heidelberg New York, p 84–85

    Chapter  Google Scholar 

  31. Shoemaker WC, Hauser CJ (1979) Critique of crystalloid versus colloid therapy in shock and shock lung. Crit Care Med 7: 117–124

    Article  PubMed  CAS  Google Scholar 

  32. Thompson WL, Bloxham DD, Rudnick MS (1977) New short-persistence hydroxyethyl starch ( HES-S ). Intensive Care Med 3: 206

    Google Scholar 

  33. Virgilio RW, Rice CL, Smith DE, James DR, Zarins CK, Hobelman CF, Peters RM (1979) Crystalloid versus colloid resuscitation: Is one better? A randomized clinical study. Surgery 85: 129–139

    Google Scholar 

  34. Watkins J, Milford Ward A (1978) Adverse response to intravenous drugs. Academic Press, London/Grune and Strutton, New York

    Google Scholar 

  35. Wells JV, King MA (1980) Adverse reactions to human plasma proteins. Anaesth Intensive Care 8: 139–144

    PubMed  CAS  Google Scholar 

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© 1983 Springer-Verlag Berlin Heidelberg

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Messmer, K. (1983). Plasma Substitutes. In: Tinker, J., Rapin, M. (eds) Care of the Critically Ill Patient. Springer, London. https://doi.org/10.1007/978-1-4471-3498-5_32

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  • DOI: https://doi.org/10.1007/978-1-4471-3498-5_32

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3500-5

  • Online ISBN: 978-1-4471-3498-5

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