Abstract
The importance of peroxisomes in central nervous system (CNS) comes from the observation that in several peroxisomal disorders, such as Zellweger syndrome, Adrenoleukodystrophy, Rhizomelyc chondrodysplasia punctata etc, severe neurological impairments were observed. They have been involved in several physiological processes in brain, such as protection against reactive oxygen species (ROS), myelinogenesis and very long chain fatty acid metabolism.
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Cimini, A., Cristiano, L., Bernardo, A., Benedetti, E., Di Loreto, S., Cerù, M.P. (2004). Peroxisomes and PPARs in Cultured Neural Cells. In: Roels, F., Baes, M., De Bie, S. (eds) Peroxisomal Disorders and Regulation of Genes. Advances in Experimental Medicine and Biology, vol 544. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9072-3_35
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DOI: https://doi.org/10.1007/978-1-4419-9072-3_35
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