Abstract
We usually use spirometry for the medical follow-up of respiratory mechanics after lung transplantation. However, especially in the first few post-operative weeks, it is easily affected by postoperative pain and the patient’s co-operation during forced breathing effort. To avoid missing out on assessing pulmonary function, we perform non-invasive forced oscillation techniques on the patients who cannot perform forced breathing maneuvers. In this paper, we discuss the application of forced oscillation techniques on a patient with suspicion of acute lung rejection, whose spirometry could not be correctly performed and seemed to be unreliable. The respiratory impedance measurements had good correlation with the patient’s clinical symptoms before and after steroid therapy. Thus, postoperative pulmonary function follow-up using forced oscillation technique was useful in assessing peripheral airway condition in critically ill patients, and may be able to detect acute rejection.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Stewart KC, Patterson GA. Current trends in lung transplantation. Am J Transplant 2001 Sep;1(3):204–210.
Bando K, Paradis IL, Komatsu K et al. Analysis of time-dependent risks for infection, rejection, and death after pulmonary transplantation. J Thorac Cardiovasc Surg 1995 Jan;109(1):49–57; discussion 57–59.
Girgis RE, Tu I, Berry GJ et al. Risk factors for the development of obliterative bronchiolitis after lung transplantation. J Heart Lung Transplant 1996 Dec;15(12):1200–1208.
Yousem SA, Berry GJ, Cagle PT et al. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: Lung rejection study group. J Heart Lung Transplant 1996 Jan;15(1 Pt 1):1–15.
Dark JH. Diagnosis of lung rejection. Lancet. 2004 May 8;363(9420):1487–1488.
DuBois AB, Brody AW, Lewis DH et al. Oscillation mechanics of lung and chest in man. J Appl Physiol 1956;8:587–594
Oostveen E, MacLeod D, Lorino H et al. The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J 2003 Dec;22(6):1026–1041.
Michaelson ED, Grassman DE, Peters WR. Pulmonary mechanics by spectral analysis of forced random nois. J Clin Invest 1975 Nov;56:1210–1230.
Landser FJ, Nagels J, Demedts M et al. A new method to determine frequency characteristics of the respiratory system. J Appl Physiol 1976 Jul;41(1):101–106.
Miller TK, Pimmel RL. Standard errors on respiratory mechanical parameters obtained by forced random excitation. IEEE Trans Biomed Eng 1983 Dec;30(12):826–832.
Smith HJ, Reinhold P, Goldman MD. Forced oscillation technique and impulse oscillometry. Eur Respir Mon 2005;31(5):72–105.
Jones HA, Donovan T, Goddard MJ et al. Use of 18FDG-PET to discriminate between infection and rejection in lung transplant recipients. Transplantation 2004 May 15;77(9):1462–1464.
Vink GR, Arets HG, van der Laag J et al. Impulse oscillometry: a measure for airway obstruction. Pediatr Pulmonol 2003 Mar;35(3):214–219.
Marotta A, Klinnert MD, Price MR et al. Impulse oscillometry provides an effective measure of lung dysfunction in 4-year-old children at risk for persistent asthma. J Allergy Clin Immunol 2003 Aug;112(2):317–22.
Beydon N, Davis SD, Lombardi E et al. An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children. Am J Respir Crit Care Med 2007 Jun 15;175(12):1304–1345.
Navajas D, Farré R, Canet J et al. Respiratory input impedance in anesthetized paralyzed patients. J Appl Physiol 1990 Oct;69(4):1372–1379
Acknowledgments
The authors would like to thank Dr. Tatsuo Fukuse and Dr. Takayuki Nakamura, Department of Thoracic Surgery, Kyoto University, for their essential and critical advice during preparation of this paper. Portions of this work were presented at the 6th International Congress on Lung Transplantation Paris, September 16–17, 2004.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer Science+Business Media, LLC
About this paper
Cite this paper
Hamakawa, H. et al. (2010). Forced Oscillation Technique as a Non-Invasive Assessment for Lung Transplant Recipients. In: Takahashi, E., Bruley, D. (eds) Oxygen Transport to Tissue XXXI. Advances in Experimental Medicine and Biology, vol 662. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1241-1_42
Download citation
DOI: https://doi.org/10.1007/978-1-4419-1241-1_42
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4419-1239-8
Online ISBN: 978-1-4419-1241-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)