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Electrochemical Detection of Secretion from Single Cells

  • Chapter
Single-Channel Recording

Abstract

Electrochemical methods based on the oxidation or reduction of specific transmitters enable exquisitely sensitive measurements of secretion from single cells. We start with a brief review of the history of their application to single cells. Then we focus on basic principles. The remainder of the chapter concerns how to make measurements and how to analyze the results.

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Author information

Author notes

  1. Dr. Robert H. Chow

    Present address: Department for Molecular Biology of Neuronal Signals, Max-Planck-Institute for Experimental Medicine, D-37075, Göttingen, Germany

  2. Dr. Ludolf Von Rüden

    Present address: Howard Hughes Medical Institute, Department of Molecular and Cellular Physiology Beckman Center, B 153 Stanford University, Stanford, CA, 94305-5428, USA

Authors and Affiliations

  1. Department of Membrane Biophysics, Max-Planck-Institute for Biophysical Chemistry, Am Faßberg, D-37077, Göttingen-Nikolausberg, Germany

    Dr. Robert H. Chow & Dr. Ludolf Von Rüden

Authors
  1. Dr. Robert H. Chow
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  2. Dr. Ludolf Von Rüden
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Editor information

Editors and Affiliations

  1. Department of Cell Physiology, Max-Planck-Institute for Medical Research, D-69120, Heidelberg, Germany

    Bert Sakmann

  2. Department of Membrane Biophysics, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg, D-37077, Göttingen, Germany

    Erwin Neher

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Chow, R.H., Von Rüden, L. (1995). Electrochemical Detection of Secretion from Single Cells. In: Sakmann, B., Neher, E. (eds) Single-Channel Recording. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1229-9_11

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  • DOI: https://doi.org/10.1007/978-1-4419-1229-9_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-1230-5

  • Online ISBN: 978-1-4419-1229-9

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