The structure of kinship links in a given population at a given time is the result of several past demographic events that shaped the population during its evolution. Many populations display particular kinship structures due to the occurrence of specific events at some point in their history, such as founder effects. Using genealogical data retrieved from the BALSAC population register, the BALSAC-RETRO genealogical database and the Early Quebec Population Register, this study focuses on the genetic consequences of the demographic settlement and expansion experienced by the Quebec population over the last four centuries. A total of 2,223 ascending genealogies were reconstructed for the purpose of this study. These genealogies have an average depth of 9.3 generations and go back as far as the early seventeenth century. Measures of kinship show that 98 percent of all pairs of subjects share at least one distant common ancestor. Virtually all genealogies (99.2 percent) contain at least one French founder. Overall, nearly 87 percent of the current gene pool is explained by French founders who came mainly from the provinces of Normandie, Ile-de-France, Aunis, Poitou, and Perche during the seventeenth century.
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References
Arcos-Burgos, M. and M. Muenke. 2002. Genetics of population isolates. Clinical Genetics 61: 233–47.
Árnason, E. 2003. Genetic heterogeneity of Icelanders. Annals of Human Genetics 67: 5–16.
Austerlitz, F. and É. Heyer. 2000. Allelic association is increased by correlation of effective family size. European Journal of Human Genetics 8: 980–5.
Beaujot, R. and D. Kerr. 2004. Population Change in Canada , 2nd edition. Oxford University Press, Don Mills.
Bouchard, G. 2004. Projet BALSAC—Rapport annuel 2003–2004. Projet BALSAC, Université du Québec à Chicoutimi, Chicoutimi (www.balsac.uqac.ca).
Bouchard, G. and M. DeBraekeleer. 1991. Histoire d’un génome. Population et génétique dans l’est du Québec. Presses de l’Université du Québec, Québec.
Bouchard, G., R. Roy, B. Casgrain, and M. Hubert. 1995. Computer in human sciences: From family reconstitution to population reconstruction, in E. Nissan and K.M. Schmidt (eds.), From information to knowledge: Conceptual and content analysis by computer ,Intellect, Oxford, pp. 201–27.
Charbonneau, H., B. Desjardins, A. Guillemette, Y. Landry, J. Légaré, and F. Nault. 1993. The First French Canadians. Pioneers in the St. Lawrence Valley. University of Delaware Press/Associated University Presses, Newark/London/Toronto.
Charbonneau, H., B. Desjardins, J. Légaré, and H. Denis. 2000. The population of the St. Lawrence Valley, 1608–1760, in M.R. Haines, R.H. Steckel et al., A population history of North America ,Cambridge University Press, Cambridge, pp. 99–142.
Desjardins, B. 1998. Le Registre de la population du Québec ancien. Annales de démographie historique 2: 215–26.
Dickinson, J.A. 1994. Les réfugiés acadiens au Québec, 1755–1775. Études canadiennes/Canadian Studies 37: 51–61.
Duchesne, L. 2004. La situation démographique au Québec, bilan 2004. Les Publications du Québec, Québec.
Gagnon, A., H. Vézina, and B. Brais. 2001. Histoire démographique et génétique du Québec. Pour la Science 287: 62–9.
Helgason, A., B. Hrafnkelsson, J.R. Gulcher, R. Ward, and K. Stefánsson. 2003a. A populationwide coalescent analysis of Icelandic matrilineal and patrilineal genealogies: Evidence for a faster evolutionary rate of mtDNA lineages than Y chromosomes. The American Journal of Human Genetics 72: 1370–88.
Helgason, A., G. Nicholson, K. Stefánsson, and P. Donnelly. 2003b. A reassessment of genetic diversity in Icelanders: Strong evidence from multiple loci for relative homogeneity caused by genetic drift. Annals of Human Genetics 67: 281–97.
Helgason, A., S. Sigurðardóttir, J. Nicholson, B. Sykes, E.W. Hill, D.G. Bradley, V. Bosnes, J.R. Gulcher, R. Ward, and K. Stefánsson. 2000. Estimating Scandinavian and Gaelic ancestry in the male settlers of Iceland. The American Journal of Human Genetics 67: 697–717.
Helgason, A., B. Yngvadóttir, B. Hrafnkelsson, J. Gulcher, and K. Stefánsson. 2005. An Icelandic example of the impact of population structure on association studies. Nature Genetics 37(1): 90–5.
Henripin, J. and Y. Péron. 1972. The demographic transition of the Province of Quebec, in D.V. Glass and R. Revelle (eds.), Population and social change , Edward Arnold, London, pp. 213–31.
Heyer, É. 1999. One founder/one gene hypothesis in a new expanding population: Saguenay (Quebec, Canada). Human Biology 71(1): 99–109.
Heyer, É., A. Sibert, and F. Austerlitz. 2005. Cultural transmission of fitness: Genes take the fast lane. Trends in Genetics 21(4): 234–9.
Heyer, É. and M. Tremblay. 1995. Variability of the genetic contribution of Quebec population founders associated to some deleterious genes. The American Journal of Human Genetics 56: 970–8.
Heyer, É., M. Tremblay, and B. Desjardins. 1997. Seventeenth-century European origins of hereditary diseases in the Saguenay population (Quebec, Canada). Human Biology 69: 209–25.
Jomphe, M. and B. Casgrain. 1997. Base de données généalogiques RETRO: Structure des données. IREP, Programme de recherches en génétique des populations, Chicoutimi.
Kere, J. 2001. Human population genetics: Lessons from Finland. Annual Review of Genomics and Human Genetics 2: 103–28.
Kittles, R.A., A.W. Bergen, M. Urbanek, M.Virkkunen, M. Linnoila, D. Goldman, and J.C. Long. 1999. Autosomal, mitochondrial, and Y chromosome DNA variation in Finland: Evidence for a male-specific bottleneck. American Journal of Physical Anthropology 108: 381–99.
Landry, Y. 1992. Orphelines en France, pionnières au Canada. Les Filles du roi au XVIIe siècle. Éditions Leméac, Montréal.
Lavoie, È-M., M. Tremblay, L. Houde, and H. Vézina. 2005. Demogenetic study of three populations within a region with strong founder effects. Community Genetics 8: 152–60.
Légaré, J. 1988. A population register for Canada under the French regime: Context, scope, content and applications. Canadian Studies in Population 15: 1–16.
Mayr, E. 1963. Animal Species and Evolution. Harvard University Press, Cambridge, MA.
McInnis, M. 2000. The population of Canada in the nineteenth century, in M.R. Haines, R.H. Steckel et al., A population history of North America, Cambridge University Press, Cambridge, pp. 371–432.
Newman, D.l., M. Abney, M.S. McPeek, C. Ober, and N.J. Cox. 2001. The importance of genealogy in determining genetic associations with complex traits. The American Journal of Human Genetics 69: 1146–8.
O’Brien, E., L.B. Jorde, B. Rönnlöf, J.O. Fellman, and A.W. Eriksson. 1988. Founder effect and genetic disease in Sottunga, Finland. American Journal of Physical Anthropology 77: 335–46.
O’Brien, E., R.A. Kerber, L.B. Jorde and A.R. Rogers. 1994. Founder effect: Assessment of variation in genetic contributions among founders. Human Biology 66: 185–204.
Peltonen, L., P. Pekkarinen, and J. Aaltonen. 1995. Messages from an isolate: Lessons from the Finnish gene pool. Biological Chemistry Hoppe-Seyler 376: 697–704.
Roberts, D.F. 1968. Genetic effects of population size reduction. Nature 220: 1084–8.
Scriver, C. 2001. Human genetics: Lessons from Quebec populations. Annual Review of Genomics and Human Genetics 2: 69–101.
Statistics Canada. 2006. www.statcan.ca.
Thompson, E.A. 1986. Pedigree Analysis in Human Genetics. Johns Hopkins University Press, Baltimore, MD.
Tremblay, M., J. Arsenault, and É. Heyer. 2003. The transmission probabilities of founder genes in five regional populations of Quebec. Population 58(3): 361–80.
Tremblay, M., M. Jomphe, and H. Vézina. 2001. Comparaison de structures patronymiques et génétiques dans la population québécoise, in G. Brunet, P. Darlu, and G. Zei (eds.), Le patronyme: Histoire, anthropologie, société ,CNRS Éditions, Paris, pp. 367–89.
Vézina, H. 1996. Démographie génétique et maladies héréditaires au Québec: L’état des recherches. Cahiers québécois de démographie 25(2): 293–322.
Vézina, H., F. Durocher, M. Dumont, L. Houde, C. Szabo, M. Tranchant, J. Chiquette, M. Plante, R. Laframboise, J. Lepine, H. Nevanlinna, D. Stoppa-Lyonnet, D. Goldgar, P. Bridge, J. Simard, and BCLC Haplotype Group; INHERIT BRCAs. 2005a. Molecular and genealogical characterization of the R1443X BRCA1 mutation in high-risk French-Canadian breast/ovarian cancer families. Human Genetics 117(2–3): 119–32.
Vézina, H., M. Tremblay, and L. Houde. 2005b. Mesures de l’apparentement biologique au Saguenay-Lac-St-Jean (Québec, Canada) à partir de reconstitutions généalogiques. Annales de démographie historique 2004(2): 67–84.
Wilhelmy, J.-P. 1984. Les mercenaires allemands au Québec du XVIIIe siècle et leur app ort à la population. Maison des mots, Beloeil.
Wright, A.F., A.D. Carothers, and M. Pirastu. 1999. Population choice in mapping genes for complex diseases. Nature Genetics 23: 397–404.
Yotova, V., D. Labuda, E. Zietkiewicz, D. Gehl, A. Lovell, J.F. Lefebvre, S. Bourgeois, É. Lemieux-Blanchard, M. Labuda, H. Vézina, L. Houde, M. Tremblay, B. Toupance, É Heyer, T.J. Hudson, and C. Laberge. 2005. Anatomy of a founder effect: Myotonic dystrophy in Northeastern Quebec. Human Genetics 117(2–3): 177–87.
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Tremblay, M., Vézina, H., Desjardins, B., Houde, L. (2008). Distant Kinship and Founder Effects in the Quebec Population. In: Bengtsson, T., Mineau, G.P. (eds) Kinship and Demographic Behavior in the Past. International Studies in Population, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6733-4_12
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