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References
Basten, C.J., Weir, B.S., and Zeng, Z.-B., 1999, QTL Cartographer, Version 1.13. Department of Statistics, North Carolina State University, Raleigh, NC.
Bino, R.J., et al., 2004, Potential of metabolomics as a functional genomics tool, Trends In Plant Science 9(9):418-425.
Brem, R.B., and Kruglyak, L., 2005, The landscape of genetic complexity across 5,700 gene expression traits in yeast, Proc. Natl. Acad. Sci. U S A. www.pnas.org/cgi/doi/10.1073/pnas.0408709102(on-line).
Brem, R.B., et al., 2002, Genetic dissection of transcriptional regulation in budding yeast, Science 296(5568):752-755.
Bushman, B.S., et al., 2002, Two loci exert major effects on chlorogenic acid synthesis in maize silks, Crop Science 42(5):1669-1678.
Byrne, P.F., et al., 1996, Quantitative trait loci and metabolic pathways: Genetic control of the concentration of maysin, a corn earworm resistance factor, in maize silks, Proceedings Of The National Academy Of Sciences Of The United States Of America 93(17):8820-8825.
Denby, K.J., Kumar, P., and Kliebenstein, D.J., 2004, Identification of Botrytis cinerea susceptibility loci in Arabidopsis thaliana, Plant Journal 38(3):473-486.
Diao, G.Q., Lin, D.Y, and Zou, F., 2004, Mapping quantitative trait loci with censored observations, Genetics 168(3):1689-1698.
Doerge, R.W., and Churchill, G.A., 1996, Permutation tests for multiple loci affecting a quantitative character, Genetics 142(1):285-94.
Douglas, S.J., et al., 2002, KNAT1 and ERECTA regulate inflorescence architecture in Arabidopsis, Plant Cell 14(3): p. 547-558.
Fiehn, O., 2001, Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks, Comparative and Functional Genomics 2(3):155-168.
Fiehn, O., et al., 2000, Metabolite profiling for plant functional genomics, Nature Biotechnology 18(11):1157-1161.
Flint, J., and Mott, R., 2001, Finding the molecular basis of quantitative traits: Successes and pitfalls, Nature Reviews Genetics 2(6):437-445.
Godiard, L., et al., 2003, ERECTA, an LRR receptor-like kinase protein controlling development pleiotropically affects resistance to bacterial wilt, Plant Journal 36(3):353-365.
Hall, R., et al., 2002, Plant metabolomics: The missing link in functional genomics strategies, Plant Cell 14(7):1437-1440.
Haley, C.S., and Knott, S.A., 1992, A simple regression method for mapping quantitative trait loci in line crosses using flanking markers, Heredity 69:315-324.
Jansen, R.C., and Nap, J.P., 2001, Genetical genomics: the added value from segregation, Trends In Genetics 17(7):388-391.
Kliebenstein, D.J., Figuth, A., and Mitchell-Olds, T., 2002a, Genetic architecture of plastic methyl jasmonate responses in Arabidopsis thaliana, Genetics 161(4):1685-1696.
Kliebenstein, D.J., Pedersen, D., and Mitchell-Olds, T., 2002b, Comparative analysis of insect resistance QTL and QTL controlling the myrosinase/glucosinolate system in Arabidopsis thaliana, Genetics 161(1):325-332.
Kliebenstein, D.J., Gershenzon, J. and Mitchell-Olds, T., 2001a, Comparative quantitative trait loci mapping of aliphatic, indolic and benzylic glucosinolate production in Arabidopsis thaliana leaves and seeds, Genetics 159(1):359-370.
Kliebenstein, D.J., et al., 2001b, Genetic control of natural variation in Arabidopsis thaliana glucosinolate accumulation, Plant Phys. 126(2):811-825.
Kliebenstein, D., 2001c, et al., Gene duplication and the diversification of secondary metabolism: side chain modification of glucosinolates in Arabidopsis thaliana, Plant Cell 13:681-693.
Kruglyak, L., and Lander, E.S, 1995, A Nonparametric Approach For Mapping Quantitative Trait Loci., Genetics 139(3):1421-1428.
Lander, E.S., and Botstein, D., 1989, Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps, Genetics 121: p. 185-199.
Lebreton, C.H., et al., 1998, A nonparametric bootstrap method for testing close linkage vs. pleiotrophy of coincident quantitative trait loci, Genetics 150(2):931-943.
Lynch, M., and Walsh, B., 1998, Genetics and analysis of quantitative traits, Sinauer Associates, Inc., Sunderland, Massachusetts.
Mackay, T.F.C., 2001, The genetic architecture of quantitative traits, Annual Review Of Genetics 35:303-339.
Mauricio, R., 2001, Mapping quantitative trait loci in plants: Uses and caveats for evolutionary biology, Nature Reviews Genetics 2(5):370-381.
McMullen, M.D., et al., 1998, Quantitative trait loci and metabolic pathways, Proceedings Of The National Academy Of Sciences Of The United States Of America 95(5):1996-2000.
Monforte, A.J., et al., 2001, Comparison of a set of allelic QTL-NILs for chromosome 4 of tomato: Deductions about natural variation and implications for germplasm utilization, Theoretical And Applied Genetics 102(4):572-590.
Morley, M., et al., 2004, Genetic analysis of genome-wide variation in human gene expression, Nature 430(7001):743-747.
Qi, Y.P., et al., 2004, ERECTA is required for protection against heat-stress in the AS1/AS2 pathway to regulate adaxial-abaxial leaf polarity in Arabidopsis, Planta 219(2):270-276.
Santos, C.A.F., and Simon, P.W., 2002, QTL analyses reveal clustered loci for accumulation of major provitamin A carotenes and lycopene in carrot roots, Molecular Genetics and Genomics 268(1):122-129.
Sax, K., 1923, The association of size differences with seed-coat pattern and pigmentation in Phaseolus vulgaris, Genetics 8:552-60.
Schadt, E.E., et al., 2003, Genetics of gene expression surveyed in maize, mouse and man, Nature 422(6929):297-302.
Shpak, E.D., Lakeman, M.B., and Torii, K.U., 2003, Dominant-negative receptor uncovers redundancy in the Arabidopsis ERECTA leucine-rich repeat receptor-like kinase signaling pathway that regulates organ shape, Plant Cell 15(5):1095-1110.
Steuer, R., et al., 2003, Interpreting correlations in metabolomic networks, Biochemical Society Transactions 31:1476-1478.
Thorup, T.A., et al., 2000, Candidate gene analysis of organ pigmentation loci in the Solanaceae, Proceedings of the National Academy of Sciences of the United States of America 97(21):11192-11197.
Tolstikov, V.V., 2003, et al., Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics, Analytical Chemistry 75(23):6737-6740.
Varona, L., et al., 2004, Derivation of a Bayes factor to distinguish between linked or pleiotropic quantitative trait loci, Genetics 166(2):1025-1035.
Weckwerth, W., et al., 2004, Differential metabolic networks unravel the effects of silent plant phenotypes, Proceedings of the National Academy of Sciences of the United States of America 101(20):7809-7814.
Xu, L., et al., 2003, Novel as1 and as2 defects in leaf adaxial-abaxial polarity reveal the requirement for ASYMMETRIC LEAVES1 and 2 and ERECTA functions in specifying leaf adaxial identity, Development 130(17):4097-4107.
Yencho, G.C., et al., 1998, QTL mapping of foliar glycoalkaloid aglycones in Solanum tuberosum x S-berthaultii potato progenies: quantitative variation and plant secondary metabolism, Theoretical And Applied Genetics 97(4):563-574.
Yvert, G., et al., 2003, Transacting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors, Nature Genetics 35(1):57-64.
Zeng, Z.-B., 1994, Precision mapping of quantitative trait loci, Genetics 136:1457-1468.
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Kliebenstein, D.J. (2007). Metabolomics and Plant Quantitative Trait Locus Analysis – The Optimum Genetical Genomics Platform?. In: Nikolau, B.J., Wurtele, E.S. (eds) Concepts in Plant Metabolomics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5608-6_3
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