Abstract
The described repeated batch mode combines the advantages of fed batch and perfusion processes. Harvesting is performed in preset intervals by a continuous-flow centrifuge (Viafuge from Carr, Pneumatic Scale INC:). The cells can be returned into the fermenter without loss of viability. The harvested medium is replaced by pre-heated fresh medium and the cell concentration for re-inoculation can be readjusted to the requested level
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Russ, K., Schlenke, P., Huchler, H., Hofer, H., Kuchenbecker, M., Fehrenbach, R. (2007). Repeated Batch Fermentation Using a Viafuge Centrifuge. In: Smith, R. (eds) Cell Technology for Cell Products., vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5476-1_88
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DOI: https://doi.org/10.1007/978-1-4020-5476-1_88
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-5475-4
Online ISBN: 978-1-4020-5476-1
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