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Characteristics of β-endorphin-induced behavioral activation and immobilization

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Endorphins in Mental Health Research

Abstract

β-endorphin produces a broad spectrum of dose-and time-related behavioral effects, ranging from hyperactivity to rigid immobility (Bloom et al., 1976; Segal et al., 1977). Our efforts to characterize further these effects and to compare them with the behavioral actions of opiates are described below.

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Author information

Authors and Affiliations

  1. Department of Psychiatry, School of MedicineUniversity of California, San Diego, La Jolla, California, 92093, USA

    David S. Segal, Ronald G. Browne, Amy Arnsten, David C. Derrington & Floyd E. Bloom

  2. Center for Behavioral Neurobiology, Salk Institute, San Diego, California, 92112, USA

    Arthur V. Davis

  3. Laboratory of Neuroendocrinology, Salk Institute, San Diego, California, 92112, USA

    Roger Guillemin & Nicholas Ling

Authors
  1. David S. Segal
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  2. Ronald G. Browne
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  3. Amy Arnsten
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  4. David C. Derrington
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  5. Floyd E. Bloom
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  6. Arthur V. Davis
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  7. Roger Guillemin
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  8. Nicholas Ling
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Editor information

Editors and Affiliations

  1. National Institute of Mental Health, Parklawn Building, 20857, Rockville, Maryland, USA

    Earl Usdin Ph.D.

  2. National Institute of Mental Health, Bethesda, Maryland, USA

    William E. Bunney Jr. M.D.

  3. Rockland Research Center, 10962, Orangeburg, New York, USA

    Nathan S. Kline M.D.

Copyright information

© 1979 The contributors

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Cite this chapter

Segal, D.S. et al. (1979). Characteristics of β-endorphin-induced behavioral activation and immobilization. In: Usdin, E., Bunney, W.E., Kline, N.S. (eds) Endorphins in Mental Health Research. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-04015-5_28

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