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An Overview of Helicobacter pylori Infection

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Helicobacter Pylori

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2283))

Abstract

Helicobacter pylori (H. pylori) represents one of the most widespread bacterial infections globally. Infection causes chronic gastritis and increases the risk of peptic ulcer disease, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. The pioneering discovery of H. pylori by Marshall and Warren in the early 1980s has initiated fervent research into H. pylori as a pathogen ever since. This chapter aims to provide an overview of our understanding of H. pylori infection and its management, with a focus on current options for diagnosis, the challenges associated with H. pylori eradication, and the need for alternative therapeutic strategies based on furthering our understanding of host: H. pylori interactions.

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Acknowledgments

Support is acknowledged from the Health Research Board and a Trinity College Dublin Provost PhD Award.

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Authors and Affiliations

  1. School of Medicine, Trinity College Dublin, Dublin, Ireland

    Rebecca FitzGerald

  2. Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin 2, Ireland

    Sinéad M. Smith

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Correspondence to Sinéad M. Smith .

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  1. Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin 2, Ireland

    Sinead M Smith

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FitzGerald, R., Smith, S.M. (2021). An Overview of Helicobacter pylori Infection. In: Smith, S.M. (eds) Helicobacter Pylori. Methods in Molecular Biology, vol 2283. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1302-3_1

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  • DOI: https://doi.org/10.1007/978-1-0716-1302-3_1

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