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Genome Variation and Precision Medicine in Systemic Lupus Erythematosus

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Precision Medicine

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2204))

Abstract

Systemic lupus erythematosus (SLE) is a complex autoimmune disease which is facing the difficulties in treatment. Genetics play an important role in SLE. Several studies have shown that genetic factors not only affect the development of SLE, but also affect its clinical progress. In this review article, we focus on exploring the influence of genetics on different aspects of SLE pathogenesis, clinical course, and treatment and will provide some references in further precision medicine for SLE patients. The coming era of precision medicine, SLE patients will be stratified by genetic profiling. This will enable us to make more effective and precise choices of treatment plan.

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Author notes

  1. Ru Yang and Yaqi Hu contributed equally to this work.

Authors and Affiliations

  1. Department of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China

    Ru Yang, Yaqi Hu & Lin Bo

Authors
  1. Ru Yang
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  2. Yaqi Hu
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  3. Lin Bo
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Editors and Affiliations

  1. Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China

    Tao Huang

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Yang, R., Hu, Y., Bo, L. (2020). Genome Variation and Precision Medicine in Systemic Lupus Erythematosus. In: Huang, T. (eds) Precision Medicine. Methods in Molecular Biology, vol 2204. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0904-0_17

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  • DOI: https://doi.org/10.1007/978-1-0716-0904-0_17

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0903-3

  • Online ISBN: 978-1-0716-0904-0

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