Thyroid ultrasound is an exquisitely sensitive technique for the detection of thyroid nodules and is able to image nodules as small as 2–3 mm. The prevalence of sonographically detected nodules that cannot be palpated is up to 50%–60% in individuals older than 60 (1). Therefore, the challenges confronting the clinician are the identification of those nodules that have a higher probability of being clinically relevant malignancies so that these can be targeted for fineneedle aspiration biopsy, and the recognition of those that may undergo sonographic surveillance. Furthermore, diffuse thyroid disorders, such as Graves’ disease and Hashimoto’s thyroiditis, image differently than the normal thyroid parenchyma, but it may be challenging to differentiate asymmetric involvement of the thyroid by one of these diffuse processes from a discrete thyroid nodule.
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Mandel, S.J., Langer, J.E., Duick, D.S. (2008). Ultrasound of Thyroid Nodules. In: Baskin, H.J., Duick, D.S., Levine, R.A. (eds) Thyroid Ultrasound and Ultrasound-Guided FNA. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-77634-7_6
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