This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Selkoe DJ. Toward a comprehensive theory for Alzheimer's disease: hypothesis—Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Ann NY Acad Sci 2000;924:17.
Solomon B, Koppel R, Hanan E, Katzav T. Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer β-amyloid peptide. Proc Natl Acad Sci U S A 1996;93:452.
Solomon B, Koppel R, Frenkel D, Hanan-Aharon E. Disaggregation of Alzheimer β-amyloid by site-directed mAb. Proc Natl Acad Sci U S A 1997;94:4109.
Brightman MW, Ishihara S, Chang L. Penetration of solutes, viruses and cells across the blood brain barrier. Curr Top Microbiol Immunol 1995;202:63.
Winter G, Griffiths AD, Hawkins RE, Hoogenboom HR. Making antibody by phage display technology. Annu Rev Immunol 1994;12:433.
Frenkel D, Solomon B. Filamentous phage as vector-mediated antibody delivery to the brain. Proc Natl Acad Sci U S A 2002;16:99(8):5675.
McCafferty J, Griffith AD, Winter G, Chiswell DJ. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 1990;348:552.
Frenkel D, Solomon B, Benhar I. Modulation of Alzheimer's β-amyloid neurotoxicity by site-directed single-chain antibody. J Neuroimmunol 2000;106:23.
Naslund J, Haroutunian V, Mohs R, et al. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 2000;283:1571.
Thorne RG, Emory CR, Ala TA, Frey WH Jr. Quantitative analysis of the olfactory pathway for drug delivery to the brain. Brain Res 1995;692:278.
Lavie V, Becker M, Cohen-Kupiec R, et al. EFRH-phage immunization of Alzheimer's disease animal model improves behavioral performance in Morris water maze trials, J Mol Neurosci 2004;24(1):105.
Draghila R, Caillaud C, Manicom R, et al. Gene delivery into the central nervous system by nasal instillation in rats. Gene Ther 1995;2:418.
Pasqualini R, Ruoslahti E. Organ targeting in vivo using phage display peptide libraries. Nature (Lond) 1996;380:364.
Greenwood J, Willis EA, Perham NR. Multiple display of foreign peptides on a filamentous bacteriophage: peptides from Plasmodium falciparum circumsporozoite protein as antigens. J Mol Biol 1991;220:821.
Scott JK, Smith GP. Searching for peptide ligands with an epitope library. Science 1990;249:386.
Zou J, Dickerson MT, Owen NK, et al. Biodistribution of filamentous phage peptide libraries in mice. Mol Biol Rep 2004;31:121.
Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996;19:312.
Chan A, Magnus T, Gold R. Phagocytosis of apoptotic inflammatory cells by microglia and modulation by different cytokines: mechanism for removal of apoptotic cells in the inflamed nervous system. Glia 2001;33:87.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2008 Springer Science+Business Media, LLC
About this paper
Cite this paper
Solomon, B. (2008). In Vivo Targeting of Amyloid Plaques Via Intranasal Administration of Phage Anti-β-Amyloid Antibodies. In: Fisher, A., Memo, M., Stocchi, F., Hanin, I. (eds) Advances in Alzheimer’s and Parkinson’s Disease. Advances in Behavioral Biology, vol 57. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72076-0_27
Download citation
DOI: https://doi.org/10.1007/978-0-387-72076-0_27
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-72074-6
Online ISBN: 978-0-387-72076-0
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)