Radionuclide lymphoscintigraphy (RNL) has progressively superseded lymphangiography and may be considered as the most advanced method for the assessment of the limb lymphatic system (1, 2).As a safe, noninvasive, and physiological method, RNL is commonly used in lymphology for the evaluation of limb lymphedemas and in oncology for the detection of the sentinel node (SN) (3, 4).However, conventional planar imaging sometimes failed to preoperatively identify the exact localization of the detected lymph nodes (5). Since 2000 (6), hybrid cameras combining a dual head gamma camera with a low-dose radiograph tube mounted on the same gantry were developed, and image fusion has been successfully introduced in clinical practice.We report our experience of this new imaging method in lymphology and oncology, particularly for the SN detection in patients with breast cancer.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Pecking AP, Cluzan RV, Desprez-Curely JP, Guérin P.: (1986) Functional study of the limb lymphatic system. Phlebology 1, 129–133.
Pecking AP, Cluzan RV, Desprez-Curely JP, Guérin P.: (1986) Indirect lymphoscintigraphy in patients with limb edemas. Phlebology 1, 215–217.
Monon DL, Wen DR, Wong JH, et al: (1992) Technical details of intraoperative lymphatic mapping for early Stage melanoma. Arch Surg 127:392–399.
Krag DN, Weaver DL, Alex JC, et al: (1993) Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg OncoI2:335–340.
Hill AD, Tran KN, Akhursl T, et al: (1999) Lessons learned from 500 cases of lymphatic mapping for breast cancer. Ann Surg 229:528–535.
Bocher M, Balan A, Krausz Y, et al: (2000) gamma camera mounted anatomical Xray tomography: technology, system characteristic and first images. Eur J Nucl med 27:619–627 2000.
Kretschmer T, Altenvoerde G, Meller J, et al: (2003) Dynamic Iymphoscintigraphy and image fusion of SPECT and pelvic CT-scans allow mapping of aberrant pelvic sentinel lymph nodes in mahgnam melanoma. Eur J Cancer 39:175–183.
Even-Sapir E, Leonan H, Lievshitz G, et al: (2003) Lymphoscintigraphy for sentinel node mapping using a hybrid SPECT/CT system. J Nucl Med 44:1413–142.
Wagner A, Schicho K, Glaser C, et al: (2004) SPECT–CT for topographic mapping of sentinel lymph nodes prior to gamma probe-guided biopsy in head and neck squamous cell carcinoma. J Craniomaxillofac Surg 32:343–349.
Kizu H, Takayama T, Fukuda M, et al: (2005) Fusion of SPECT and multidetector CT images for accurate localization of pelvic sentinel lymph nodes in prostate cancer patients. J. Nucl Med Technol 33:78–82.
Zhang WJ, Zheng R, Wu LY, et al: (2006) Clinical application of sentinel lymph node detection to early stage cervical cancer. Ai Zheng 25:224–228.
Sherif A, Garske V, Torre Mde L, et al: (2006) Hybrid SPECT. CT: an additional technique for sentinel node detection of patients with invasive bladder cancer. Eur Urol 50:83–91.
Lerman H, Metser U.l, Lievshitz G, et al: (2006) lymphoscintigraphic sentinel node identification in patients with breast cancer: the role of SPECT–CT Eur Nucl Med Mol Imaging 33:329–337.
Husarik DB, Steinert HC. (2007) Single Photon Emission Tomography/Computed Tomography for sentinel node mapping in breast cancer. Semin Nucl Med. 37:29–33.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Pecking, A.P., Wartski, W., Cluzan, R.V., Bellet, D., Albérini, J.L. (2007). SPECT–CT Fusion Imaging Radionuclide Lymphoscintigraphy: Potential for Limb Lymphedema Assessment and Sentinel Node Detection In Breast Cancer. In: Leong, S.P.L. (eds) Cancer Metastasis And The Lymphovascular System: Basis For Rational Therapy. Cancer Treatment and Research, vol 135. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-69219-7_6
Download citation
DOI: https://doi.org/10.1007/978-0-387-69219-7_6
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-69218-0
Online ISBN: 978-0-387-69219-7
eBook Packages: MedicineMedicine (R0)