Synonyms
NEMS-based biosensors; Impedance biosensors; Nanobiosensors for nano- and microfluidics; Biological sensors; Lab-on-a-Chip; Diagnostic biochip; MEMS biosensor
Definition
Biosensors are bioanalytical systems defined by the integration of four key components: sample presentation, biotransduction, instrumentation, and data output. Central to the biosensor system is the biotransducerthat converts the activity (concentration) of the targeted analyte into a proportional signal via an intimate combination of a biological recognition membrane layer and a physicochemical transducer. The biological recognition membrane provides its specificity by the use of biomolecules such as DNA, RNA, PNA, enzymes, antibodies, enzyme-linked antibodies, and receptors, and may use subcellular fragments such as mitochondria and cell membrane components (receptors), whole cells (bacteria or mammalian cells), and/or tissue slices (liver, brain, etc.). An impedimetric biosensor is constructed by...
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Yang, L., Guiseppi-Elie, A. (2008). Impedimetric Biosensors for Nano- and Microfluidics. In: Li, D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-48998-8_686
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DOI: https://doi.org/10.1007/978-0-387-48998-8_686
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-32468-5
Online ISBN: 978-0-387-48998-8
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