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Tumors of the Endocrine System

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Cancer Grading Manual

Abstract

The grading of endocrine gland tumors has been difficult, inconsistent, and unrewarding. While the reasons for these problems vary from organ to organ, and from one tumor type to another, in general grading has been hampered by the following issues:

  • In many endocrine organs, the transition of hyperplasia to benign neoplasia and then to malignancy includes a spectrum of morphologic changes that are not always easily defined.

  • The proposed grading systems are often complex and include a number of variants that are not acceptable to all pathologists. The lack of consensus among pathologists has been one of the main hindrances to grading endocrine tumors.

  • The correlation between the microscopic grading and the prognosis of tumors is often poor, and therefore with a few notable exceptions, clinicians do not find the pathologic grading of endocrine tumors to be as useful as that for tumors of other organs systems.

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Authors and Affiliations

  1. Department of Pathology, The University of Kansas School of Medicine, Kansas City, KS, USA

    Ivan Damjanov MD, PhD (Professor of Pathology)

Authors
  1. Ivan Damjanov MD, PhD
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Editors and Affiliations

  1. School of Medicine, The University of Kansas, Kansas City, Kansas

    Ivan Damjanov MD, PhD (Professor of Pathology) & Fang Fan MD, PhD (Assistant Professor of Pathology) (Professor of Pathology) &  (Assistant Professor of Pathology)

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Damjanov, I. (2007). Tumors of the Endocrine System. In: Damjanov, I., Fan, F. (eds) Cancer Grading Manual. Springer, New York, NY. https://doi.org/10.1007/978-0-387-33751-7_8

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  • DOI: https://doi.org/10.1007/978-0-387-33751-7_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-33750-0

  • Online ISBN: 978-0-387-33751-7

  • eBook Packages: MedicineMedicine (R0)

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