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Echinostomes: genomics and proteomics

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The Biology of Echinostomes

Abstract

Echinostomes are excellent models to study host-parasite interactions in intestinal helminthiases. In this chapter, data available from genomic and proteomic studies are analyzed in detail to indicate advantages and pitfalls in the research using these organisms. The lack of a genome sequence project and the low number of sequences deposited in the databases not only affect the genomic studies but also debilitate proteomic findings since in most cases, although good spectrometric data can be obtained, the available database often fail to identify the protein from the peptides obtained.

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Acknowledgments

Dr. Lynne Yenush is thanked for critically reading the manuscript. Financial support was obtained from the Spanish Ministry of Education and Science (Madrid, Spain), grant CGL2005–02321/BOS; Conselleria d’Educació, Generalitat Valenciana (Valencia, Spain), grants GV07/006 and ACOMP07/071; and Universitat de València (Valencia, Spain) grant Accions Especials 20050201.

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  1. Departamento de Biología Celular y Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot-Valencia, Spain

    Antonio Marcilla

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    Marcilla, A. (2009). Echinostomes: genomics and proteomics. In: Toledo, R., Fried, B. (eds) The Biology of Echinostomes. Springer, New York, NY. https://doi.org/10.1007/978-0-387-09577-6_9

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