Skip to main content

Validation of a Light Aspiration Device for In Vivo Soft Tissue Characterization (LASTIC)

  • Chapter
  • First Online:
Soft Tissue Biomechanical Modeling for Computer Assisted Surgery

Abstract

In vivo characterization of soft tissue is a key step towards accurate biomechanical simulation enabling planning and intra-operative assisted surgery. This chapter presents the new version of LASTIC, a device measuring soft tissue deformations using a negative pressure. Its capabilities are compared with standard tensile tests on five samples with different elastic properties, i.e. Young modulus, from 10 kPa to 1 MPa, in order to estimate its accuracy and define the functional measurement range. Results show that LASTIC overestimates Young modulus by an average of 24% compared to the tensile devices. This error, although rather large, allows a first estimation of the elastic modulus of different materials, especially living tissues, even during surgery. Directions for improvements are given that will allow for better patient-specific biomechanical simulations of soft tissues.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Meunier, L., Chagnon, G., Favier, D., Orgéas, L., Vacher, P.: Mechanical experimental characterisation and numerical modelling of an unfilled silicone rubber. Polym. Test. 27, 765–777 (2008)

    Article  Google Scholar 

  2. Schiavone, P., Boudou, T., Ohayon, J., Payan, Y.: In vivo measurement of the human soft tissues constitutive laws. Applications to computer aided surgery. Comput. Methods Biomech. Biomed. Eng. 10(1), 185–186 (2007)

    Article  Google Scholar 

  3. Schiavone, P., Boudou, T., Promayon, E., Perrier, P., Payan Y.: A light sterilizable pipette device for the in vivo estimation of human soft tissues constitutive laws. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE EMBS, pp. 4298–4301 (2008)

    Google Scholar 

  4. Schiavone, P., Chassat, F., Boudou, T., Promayon, E., Valvidia, F., Payan, Y.: In vivo measurement of human brain elasticity using a light aspiration device. Med. Image Anal. 13, 673–678 (2009)

    Article  Google Scholar 

  5. Schiavone, P., Promayon, E. Payan, Y.: LASTIC: a light aspiration device for in vivo soft tissue characterization. In: Biomedical Simulation: 5th International Symposium, ISBMS 2010, vol. 5958, pp. 1–10 (2010)

    Google Scholar 

  6. Treloar, L.R.G.: The elasticity of a network of long chains molecules I and II. Trans. Faraday Soc. 39, 236–246 (1943)

    Google Scholar 

  7. Vuskovic, V.: Device for in vivo measurement of mechanical properties of internal human soft tissues http://e-collection.library.ethz.ch/view/eth:24411(2001)

  8. Zhao, R., Wyss, K., Simmons, C.A.: Comparison of analytical and inverse finite element approaches to estimate cell viscoelastic properties by micropipette aspiration. J. Biomech. 42(16), 2768–2773 (2009)

    Article  Google Scholar 

Download references

Acknowledgments

ANR TecSan IDS, Région Rhône-Alpes (projet SIMED, Cluster ISLE), Amandine Dufaug and Luc Maréchal (SYMME), Jérôme Giraud (LSP), Jacques Ohayon (TIMC).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vincent Luboz .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Luboz, V. et al. (2012). Validation of a Light Aspiration Device for In Vivo Soft Tissue Characterization (LASTIC). In: Payan, Y. (eds) Soft Tissue Biomechanical Modeling for Computer Assisted Surgery. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/8415_2012_123

Download citation

  • DOI: https://doi.org/10.1007/8415_2012_123

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-29013-8

  • Online ISBN: 978-3-642-29014-5

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics