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Attention Deficit Hyperactivity Disorder and Substance Use Disorders

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Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its Treatment

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 9))

Abstract

During the past two decades, there has been an increased recognition that Attention Deficit Hyperactivity Disorder (ADHD) is overrepresented in treatment and community populations of both adolescents and adults with substance use disorders (SUDs). This chapter explores this relationship, including a review of the prevalence of this comorbidity, ADHD and the risk for the development of SUDs. Possible neurobiological underpinnings of the relationship are also discussed. Because of the salience of the association between smoking (tobacco) and ADHD, this topic is included in the discussion of substance use and SUDs.

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Abbreviations

APA:

American Psychiatric Association

AUD:

Alcohol use disorder

CBT:

Cognitive behavioral therapy

CD:

Conduct disorder

CPT:

Continuous performance test

DA:

Dopamine

DAT:

Dopamine transporter

DEA:

Drug Enforcement Agency

FDA:

Food and Drug Administration

MAO-A:

Monoamine Oxidase (A isoform)

MDA:

Multi-modal treatment study of ADHD (MTA)

MI/CBT:

Motivational interviewing/cognitive behavioral therapy

MPH:

Methamphetamine

OR:

Odds ratio

PET:

Positron emission tomography

SODAS:

Spheroidal oral drug absorption system

SPECT:

Single photon emission computerized tomography

SUD:

Substance abuse disorder

VNTR:

Variable-number tandem repeat

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  1. University of Texas Health Science Center at Houston, Houston, Texas, USA

    Oscar G. Bukstein

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Correspondence to Oscar G. Bukstein .

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  1. , Dept of Neurosci, Physiol & Pharmacol, University College London, Gower Street, London, WC1E6BT, United Kingdom

    Clare Stanford

  2. , Human Development & Applied Psychology, The Ontario Institute for Studies in Edu, Bloor Street West 252, Toronto, M5S1V6, Canada

    Rosemary Tannock

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Bukstein, O.G. (2011). Attention Deficit Hyperactivity Disorder and Substance Use Disorders. In: Stanford, C., Tannock, R. (eds) Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its Treatment. Current Topics in Behavioral Neurosciences, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2011_148

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