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Multifunctional Magnetic Nanoparticles-Labeled Mesenchymal Stem Cells for Hyperthermia and Bioimaging Applications

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Stem Cell Nanotechnology

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2125))

Abstract

Magnetic nanoparticles have demonstrated considerable capacity for theranosis purposes due to their unique characteristics, including magnetic properties, comparable size to biomolecules, favorable conjugations of drugs and biomolecules, ability to labeling, and capability of sensing, separation, detection, and targeted drug delivery. They could be exploited in magnetic resonance imaging as the contrast agents and also warmed as exposed to an external magnetic AC field that could be applied in hyperthermia. Here, progresses and advances in the strategy and assembly of fluorescent magnetic nanoparticles are presented for stem cell tracing and drugs/biomolecules targeting into cells.

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Author information

Authors and Affiliations

  1. Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, Iran

    Sadegh Ghorbanzade, Seyed Morteza Naghib & Fatemeh Sadat Fateminia

  2. Department of Electrical Engineering, Iran University of Science and Technology, Tehran, Iran

    Ali Sadr

  3. Interdisciplinary Technologies Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran

    Fatemeh Sadat Fateminia & Keivan Majidzadeh-A

  4. Research Laboratory of Real Samples Analysis, Faculty of Chemistry, Iran University of Science and Technology (IUST), Tehran, Iran

    Ali Ghaffarinejad

  5. Electroanalytical Chemistry Research Center, Iran University of Science and Technology (IUST), Tehran, Iran

    Ali Ghaffarinejad

  6. BioMEMS and Bioinspired Microfluidic Laboratory, Department of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, AB, Canada

    Amir Sanati-Nezhad

  7. Center for BioEngineering Research and Education, University of Calgary, Calgary, AB, Canada

    Amir Sanati-Nezhad

Authors
  1. Sadegh Ghorbanzade
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  2. Seyed Morteza Naghib
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  3. Ali Sadr
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  4. Fatemeh Sadat Fateminia
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  5. Ali Ghaffarinejad
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  6. Keivan Majidzadeh-A
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  7. Amir Sanati-Nezhad
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Corresponding authors

Correspondence to Keivan Majidzadeh-A or Amir Sanati-Nezhad .

Editor information

Editors and Affiliations

  1. Ottawa, ON, Canada

    Kursad Turksen

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Ghorbanzade, S. et al. (2019). Multifunctional Magnetic Nanoparticles-Labeled Mesenchymal Stem Cells for Hyperthermia and Bioimaging Applications. In: Turksen, K. (eds) Stem Cell Nanotechnology. Methods in Molecular Biology, vol 2125. Humana, New York, NY. https://doi.org/10.1007/7651_2019_271

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  • DOI: https://doi.org/10.1007/7651_2019_271

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0359-8

  • Online ISBN: 978-1-0716-0360-4

  • eBook Packages: Springer Protocols

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