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The Development of Iron Catalysts for Cross-Coupling Reactions

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Iron Catalysis II

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 50))

Abstract

Cross-coupling between organometallic nucleophiles and organic electrophiles is currently one of the most widely investigated areas of organic homogeneous catalysis with iron. This overview charts the development and application of iron catalysts for cross-coupling reactions, focusing predominantly on findings over the last 5 years.

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Abbreviations

acac:

Acetylacetonate

Ar:

Aryl

9-BBN:

9-Borabicyclo[3.3.1]nonane

bmim:

1-Butyl-3-methylimidazolium

cat:

Catalyst

Cp:

Cyclopentadienyl

dpbz:

1,2-Bis(diphenylphosphino)benzene

dppe:

1,2-Bis(diphenylphosphino)ethane

dppp:

1,3-Bis(diphenylphosphino)propane

EPR:

Electron paramagnetic resonance

Mes:

Mesityl, 2,4,6-trimethylphenyl

NHC:

N-heterocyclic carbene

NMP:

N-methylpyrrolidone

salen:

N,N′-ethylenebis(salicylimine)

Tf:

Triflate

THF:

Tetrahydrofuran

TMEDA:

N,N,N′,N′-tetramethyl-1,2-ethylenediamine

TMS:

Trimethylsilyl

Ts:

Tosyl

Xantphos:

4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene

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  1. School of Chemistry, University of Bristol, Cantock’s Close, BS8 1TS, Bristol, UK

    Robin B. Bedford & Peter B. Brenner

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  1. Robin B. Bedford
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  1. Dept. of Chemistry and Biochemistry, University of Missouri - St. Louis, One University Boulevard, St. Louis, Missouri, USA

    Eike Bauer

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Bedford, R.B., Brenner, P.B. (2015). The Development of Iron Catalysts for Cross-Coupling Reactions. In: Bauer, E. (eds) Iron Catalysis II. Topics in Organometallic Chemistry, vol 50. Springer, Cham. https://doi.org/10.1007/3418_2015_99

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