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Chelation-Assisted Arylation via C–H Bond Cleavage

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Directed Metallation

Part of the book series: Topics in Organometallic Chemistry ((TOPORGAN,volume 24))

Abstract

Regioselectivity was achieved in transition-metal-catalyzed arylation reactions via C–H bond cleavage through the use of chelation-assistance. Palladium, rhodium, and ruthenium complexes proved useful for the development of broadly applicable methodologies for intermolecular direct arylation reactions. These include protocols for direct arylation reactions using aryl chlorides and tosylates as well as transformations that proceed through the cleavage of unactivated C(sp3)–H bonds.

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  1. Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstr. 2, 37077, Göttingen, Germany

    Lutz Ackermann

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  1. Lutz Ackermann
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Naoto Chatani

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Ackermann, L. (2007). Chelation-Assisted Arylation via C–H Bond Cleavage. In: Chatani, N. (eds) Directed Metallation. Topics in Organometallic Chemistry, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3418_2007_062

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