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Measurement of Ventricular Wall Motion, Epicardial Electrical Mapping, and Myocardial Fiber Angles in the Same Heart

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Functional Imaging and Modeling of the Heart (FIMH 2001)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2230))

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Abstract

Methods for the precise measurement of three dimensional myocardial motion non-invasivley with MRI have recently been developed. These methods use a technique called “presaturation tagging” to mark the myocardium, and rapid MRI to track the motion of these markers. A unique capability of this method is the production of strain images representing the local deformation of the myocardium. These images clearly show the sequence of events during the activation of the heart, and can demonstrate abnormalities caused by asynchronous electrical activation or ischemia. Coupled with the near simultaneous mapping of electrical depolarization with an epicardial sock array, we can investigate the relationship between electical activity and mechanical function on a local level. Registered fiber angle maps can be obtained in the same heart with diffusion MRI to assist in the construction of the mechanoelectrical model of the whole heart.

Correspondence: Elliot R. McVeigh, PhD. NHLBI, Building 10, Room B1D416, Bethesda, MD, 20892

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References

  1. Axel L and Dougherty L. MR imaging of motion with spatial modulation of magnetization. Radiology 1989; 171: 841–5.

    Google Scholar 

  2. Brooks DH and MacLeod RS. Electrical Imaging of the Heart. IEEE Signal Processing Magazine 1997; 14: 24–42.

    Article  Google Scholar 

  3. Burnes JE, Taccardi B, and Rudy Y. A noninvasive imaging modality for cardiac arrhythmias. Circulation 2000; 102: 2152–8.

    Google Scholar 

  4. Faris O, Evans F, Ozturk C, Ennis D, Taylor J, and McVeigh ER. Correlation Between Electrical and Mechanical Activation in the Paced Canine Heart. International Society of Magnetic Resonance in Medicine: Book of Abstracts 2001.

    Google Scholar 

  5. Franz MR, Cima R, Wang D, Profitt D, and Kurz R. Electrophysiological effects of myocardial stretch and mechanical determinants of stretch-activated arrhythmias [published erratum appears in circulation 1992 nov;86(5):1663]. Circulation 1992; 86: 968-78.

    Google Scholar 

  6. Garrido L, Wedeen VJ, Kwong KK, Spencer UM, and Kantor HL. Anisotropy of water diffusion in the myocardium of the rat. Circ Res 1994; 74: 789–93.

    Google Scholar 

  7. Guttman MA, Prince JL, and McVeigh ER. Tag and contour detection in tagged MR images of the left ventricle. IEEE Trans.Med.Imag. 1994; 13: 74–88.

    Article  Google Scholar 

  8. Liu ZW, Jia P, Biblo LA, Taccardi B, and Rudy Y. Endocardial potential mapping from a noncontact nonexpandable catheter: a feasibility study. Ann.Biomed.Eng 1998; 26: 994–1009.

    Article  Google Scholar 

  9. MacLeod RS and Brooks DH. Recent progress in inverse problems in electrocardiology. IEEE Eng Med.Biol.Mag. 1998; 17: 73–83.

    Article  Google Scholar 

  10. McVeigh ER. MRI of myocardial function: motion tracking techniques. Magn.Reson.Imag. 1996; 14: 137–50.

    Article  Google Scholar 

  11. McVeigh ER, Prinzen FW, Wyman BT, Tsitlik JE, Halperin HR, and Hunter WC. Imaging asynchronous mechanical activation of the paced heart with tagged MRI. Magn Reson.Med. 1998; 39: 507–13.

    Article  Google Scholar 

  12. Ozturk C and McVeigh ER. Four-dimensional B-spline based motion analysis of tagged MR images: introduction and in vivo validation. Phys.Med.Biol. 2000; 45: 1683–702.

    Article  Google Scholar 

  13. Salama G. Optical measurement of transmembrane potential. In: Loew L, ed. Spectroscopic Membrane Probes Vol. III. CRC, Boca Raton. 1988, 137–99.

    Google Scholar 

  14. Scollan DF, Holmes A, Winslow R, and FJ. Histological validation of myocardium microstructure obtained from diffusion tensor magnetic resonance imaging. Am J Physiol 1998; 275: H2308–H2318.

    Google Scholar 

  15. Wyman BT, Hunter WC, Prinzen FW, and McVeigh ER. Mapping propagation of mechanical activation in the paced heart with MRI tagging. Am.J.Physiol 1999; 276: H881–H891.

    Google Scholar 

  16. Zabel M, Koller BS, Sachs F, and Franz MR. Stretch-induced voltage changes in the isolated beating heart: importance of the timing of stretch and implications for stretchactivated ion channels. Cardiovasc.Res. 1996; 32: 120–30.

    Article  Google Scholar 

  17. Zerhouni EA, Parish DM, Rogers WJ, Yang A, and Shapiro EP. Human heart: tagging with MR imaging-a method for noninvasive assessment of myocardial motion. Radiology 1988; 169: 59–63.

    Google Scholar 

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© 2001 Springer-Verlag Berlin Heidelberg

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McVeigh, E., Faris, O., Ennis, D., Helm, P., Evans, F. (2001). Measurement of Ventricular Wall Motion, Epicardial Electrical Mapping, and Myocardial Fiber Angles in the Same Heart. In: Katila, T., Nenonen, J., Magnin, I.E., Clarysse, P., Montagnat, J. (eds) Functional Imaging and Modeling of the Heart. FIMH 2001. Lecture Notes in Computer Science, vol 2230. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45572-8_11

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  • DOI: https://doi.org/10.1007/3-540-45572-8_11

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42861-9

  • Online ISBN: 978-3-540-45572-1

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