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Dendritic Cell Interactions and Cytokine Production

  • Conference paper
Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 56))

Abstract

The dendritic cell lineage comprises cells at various stages of functional maturation that are able to induce and regulate the immune response against antigens and thus function as initiators of protective immunity. The signals that determine the given dendritic cell functions depend mostly on the local microenvironment and on the interaction between dendritic cells and microorganisms. These interactions are complex and very different from one pathogen to another; nevertheless, both shared and unique responses have been observed using global genomic analyses. In this review, we have focused on the study of host-pathogen interactions using a genome-wide transcriptional approach with a focus on cytokine family members.

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Authors and Affiliations

  1. Department of Biotechnology Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, 20126, Milan, Italy

    M. Foti, F. Granucci & P. Ricciardi-Castagnoli

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  1. M. Foti
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  2. F. Granucci
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  3. P. Ricciardi-Castagnoli
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Editors and Affiliations

  1. Berlex Biosciences, 2600 Hilltop Drive, PO Box 4099, Richmond, CA, 94804-0099, USA

    R. Numerof

  2. University of Colorado Health Sciences Center, 4200 East Ninth Ave., B168, Denver, CO, 80262, USA

    C. A. Dinarello

  3. Corporate Research Business Area Dermatology, Schering AG, Müllerstr. 178, 13342, Berlin, Germany

    K. Asadullah

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© 2005 Springer-Verlag Berlin Heidelberg

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Foti, M., Granucci, F., Ricciardi-Castagnoli, P. (2005). Dendritic Cell Interactions and Cytokine Production. In: Numerof, R., Dinarello, C.A., Asadullah, K. (eds) Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases. Ernst Schering Research Foundation Workshop, vol 56. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-37673-9_4

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  • DOI: https://doi.org/10.1007/3-540-37673-9_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-25427-0

  • Online ISBN: 978-3-540-37673-6

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